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F6UUY1

- F6UUY1_XENTR

UniProt

F6UUY1 - F6UUY1_XENTR

Protein
Submitted name:

Uncharacterized protein

Gene

gad2

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. carboxy-lyase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. gamma-aminobutyric acid biosynthetic process Source: Ensembl
    2. neurotransmitter biosynthetic process Source: Ensembl

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    ReactomeiREACT_219860. GABA synthesis.
    REACT_223518. GABA synthesis, release, reuptake and degradation.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:gad2Imported
    OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
    Taxonomic identifieri8364 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
    ProteomesiUP000008143: Unplaced

    Organism-specific databases

    XenbaseiXB-GENE-976598. gad2.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00730000110441.
    KOiK01580.
    OMAiWRAKGTT.
    OrthoDBiEOG7H1JM3.
    TreeFamiTF314688.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F6UUY1-1 [UniParc]FASTAAdd to Basket

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    MASPGSGFWP FGAEEGNKEA ENPGTAKAWC QVAQKFTGGI SSKLCSLLYG    50
    EGERAPGSVG KNEKDELGSG ERGMACNCDT KACGCRKGEA NFSLLYSTDL 100
    LPSKNGEGVT MTFLQDVIDV LLQYVVQTFD RSTKVIDFHY PNELLQAYNW 150
    ELSEQPQSLD GILLNCKTTL KYAIKTGHPR YFNQLSTGLD MVGLAADWLT 200
    STANTNMFTY EIAPVFVLLE YVTLKKMREM IGWPGGSGDG IFSPGGAISN 250
    LYAMLIARFK MFPEVKEKGM AALPRLVAFT SEHSHFSVKK GAAALGIGTD 300
    SVILIKADER GRLIPSDLER RIIEAKQNGY VPFFVSATAG TTVYGAFDPL 350
    VSIADICKKY RIWMHVDAAW GGGLLMSRKH KWKLNGADRA NSVTWNPHKM 400
    MGVPLQCSAL LVREEGLMQN CNQMHASYLF QQDKHYDLSY DTGDKALQCG 450
    RHVDIFKLWL MWRAKGTTGF EAHIDKCLEL SEYLYNKIKN REGYEMVIEG 500
    KPQHTNVCFW YVPPSLRNME DNEERMNRLS KVAPIIKARM MEYGTTMVSY 550
    QPHGDKGNFF RMVISNPAAA HQDIDFLIEE IERLGQDL 588
    Length:588
    Mass (Da):65,720
    Last modified:July 27, 2011 - v1
    Checksum:i14B23FFA01451AAF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAMC01019746 Genomic DNA. No translation available.
    AAMC01019747 Genomic DNA. No translation available.
    AAMC01019748 Genomic DNA. No translation available.
    AAMC01019749 Genomic DNA. No translation available.
    RefSeqiXP_002933179.1. XM_002933133.2.

    Genome annotation databases

    EnsembliENSXETT00000040531; ENSXETP00000040531; ENSXETG00000026517.
    GeneIDi100493806.
    KEGGixtr:100493806.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAMC01019746 Genomic DNA. No translation available.
    AAMC01019747 Genomic DNA. No translation available.
    AAMC01019748 Genomic DNA. No translation available.
    AAMC01019749 Genomic DNA. No translation available.
    RefSeqi XP_002933179.1. XM_002933133.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSXETT00000040531 ; ENSXETP00000040531 ; ENSXETG00000026517 .
    GeneIDi 100493806.
    KEGGi xtr:100493806.

    Organism-specific databases

    CTDi 2572.
    Xenbasei XB-GENE-976598. gad2.

    Phylogenomic databases

    GeneTreei ENSGT00730000110441.
    KOi K01580.
    OMAi WRAKGTT.
    OrthoDBi EOG7H1JM3.
    TreeFami TF314688.

    Enzyme and pathway databases

    Reactomei REACT_219860. GABA synthesis.
    REACT_223518. GABA synthesis, release, reuptake and degradation.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUN-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiF6UUY1_XENTR
    AccessioniPrimary (citable) accession number: F6UUY1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3