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Protein
Submitted name:

Uncharacterized protein

Gene

gad2

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

ReactomeiREACT_272690. GABA synthesis, release, reuptake and degradation.
REACT_336068. GABA synthesis.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:gad2Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
ProteomesiUP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-976598. gad2.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000040531.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119205.
InParanoidiF6UUY1.
KOiK01580.
OMAiWRAKGTT.
OrthoDBiEOG7H1JM3.
TreeFamiTF314688.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6UUY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASPGSGFWP FGAEEGNKEA ENPGTAKAWC QVAQKFTGGI SSKLCSLLYG
60 70 80 90 100
EGERAPGSVG KNEKDELGSG ERGMACNCDT KACGCRKGEA NFSLLYSTDL
110 120 130 140 150
LPSKNGEGVT MTFLQDVIDV LLQYVVQTFD RSTKVIDFHY PNELLQAYNW
160 170 180 190 200
ELSEQPQSLD GILLNCKTTL KYAIKTGHPR YFNQLSTGLD MVGLAADWLT
210 220 230 240 250
STANTNMFTY EIAPVFVLLE YVTLKKMREM IGWPGGSGDG IFSPGGAISN
260 270 280 290 300
LYAMLIARFK MFPEVKEKGM AALPRLVAFT SEHSHFSVKK GAAALGIGTD
310 320 330 340 350
SVILIKADER GRLIPSDLER RIIEAKQNGY VPFFVSATAG TTVYGAFDPL
360 370 380 390 400
VSIADICKKY RIWMHVDAAW GGGLLMSRKH KWKLNGADRA NSVTWNPHKM
410 420 430 440 450
MGVPLQCSAL LVREEGLMQN CNQMHASYLF QQDKHYDLSY DTGDKALQCG
460 470 480 490 500
RHVDIFKLWL MWRAKGTTGF EAHIDKCLEL SEYLYNKIKN REGYEMVIEG
510 520 530 540 550
KPQHTNVCFW YVPPSLRNME DNEERMNRLS KVAPIIKARM MEYGTTMVSY
560 570 580
QPHGDKGNFF RMVISNPAAA HQDIDFLIEE IERLGQDL
Length:588
Mass (Da):65,720
Last modified:July 27, 2011 - v1
Checksum:i14B23FFA01451AAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01019746 Genomic DNA. No translation available.
AAMC01019747 Genomic DNA. No translation available.
AAMC01019748 Genomic DNA. No translation available.
AAMC01019749 Genomic DNA. No translation available.
RefSeqiXP_002933179.1. XM_002933133.2.

Genome annotation databases

EnsembliENSXETT00000040531; ENSXETP00000040531; ENSXETG00000026517.
GeneIDi100493806.
KEGGixtr:100493806.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01019746 Genomic DNA. No translation available.
AAMC01019747 Genomic DNA. No translation available.
AAMC01019748 Genomic DNA. No translation available.
AAMC01019749 Genomic DNA. No translation available.
RefSeqiXP_002933179.1. XM_002933133.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000040531.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000040531; ENSXETP00000040531; ENSXETG00000026517.
GeneIDi100493806.
KEGGixtr:100493806.

Organism-specific databases

CTDi2572.
XenbaseiXB-GENE-976598. gad2.

Phylogenomic databases

GeneTreeiENSGT00760000119205.
InParanoidiF6UUY1.
KOiK01580.
OMAiWRAKGTT.
OrthoDBiEOG7H1JM3.
TreeFamiTF314688.

Enzyme and pathway databases

ReactomeiREACT_272690. GABA synthesis, release, reuptake and degradation.
REACT_336068. GABA synthesis.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUN-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF6UUY1_XENTR
AccessioniPrimary (citable) accession number: F6UUY1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 22, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.