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Protein
Submitted name:

Spliceosome RNA helicase DDX39B

Gene

DDX39B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Spliceosome RNA helicase DDX39BImported
Gene namesi
Name:DDX39BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:13917. DDX39B.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198563.
ENSG00000215425.
ENSG00000225073.
ENSG00000225859.
ENSG00000229496.
ENSG00000230624.
ENSG00000235439.

PTM / Processingi

Proteomic databases

MaxQBiF6UJC5.
PeptideAtlasiF6UJC5.
PRIDEiF6UJC5.

Expressioni

Gene expression databases

BgeeiENSG00000198563.
ExpressionAtlasiF6UJC5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF6UJC5.
SMRiF6UJC5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 171Helicase ATP-bindingInterPro annotationAdd BLAST117
Domaini183 – 245Helicase C-terminalInterPro annotationAdd BLAST63

Phylogenomic databases

GeneTreeiENSGT00830000128348.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F6UJC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWTMSSWTMK MMRWRQQLGE MGLRPLPRRM SRAPMSPSTA LAFVTSCSSQ
60 70 80 90 100
SCSGPLSTVA LSIRQKVAVF FGGLSIKKDE EVLKKNCPHI VVGTPGRILA
110 120 130 140 150
LARNKSLNLK HIKHFILDEC DKMLEQLDMR RDVQEIFRMT PHEKQVMMFS
160 170 180 190 200
ATLSKEIRPV CRKFMQDPME IFVDDETKLT LHGLQQYYVK LKDNEKNRKL
210 220 230 240
FDLLDVLEFN QVVIFVKSVQ RCIALAQLLV EQNFPAIAIH RGMPQ
Length:245
Mass (Da):28,300
Last modified:July 27, 2011 - v1
Checksum:i9EA8162194217844
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei245Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662801 Genomic DNA. No translation available.
AL662847 Genomic DNA. No translation available.
BX001040 Genomic DNA. No translation available.
BX248516 Genomic DNA. No translation available.
BX927320 Genomic DNA. No translation available.
CR753820 Genomic DNA. No translation available.
CR753864 Genomic DNA. No translation available.
CR753892 Genomic DNA. No translation available.
CR942185 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000415390; ENSP00000393172; ENSG00000230624.
ENST00000427425; ENSP00000412286; ENSG00000225073.
ENST00000427489; ENSP00000410915; ENSG00000235439.
ENST00000431908; ENSP00000408000; ENSG00000198563.
ENST00000446328; ENSP00000414096; ENSG00000215425.
ENST00000448000; ENSP00000411967; ENSG00000225859.
ENST00000452792; ENSP00000398978; ENSG00000229496.
UCSCiuc063nba.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662801 Genomic DNA. No translation available.
AL662847 Genomic DNA. No translation available.
BX001040 Genomic DNA. No translation available.
BX248516 Genomic DNA. No translation available.
BX927320 Genomic DNA. No translation available.
CR753820 Genomic DNA. No translation available.
CR753864 Genomic DNA. No translation available.
CR753892 Genomic DNA. No translation available.
CR942185 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF6UJC5.
SMRiF6UJC5.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF6UJC5.
PeptideAtlasiF6UJC5.
PRIDEiF6UJC5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000415390; ENSP00000393172; ENSG00000230624.
ENST00000427425; ENSP00000412286; ENSG00000225073.
ENST00000427489; ENSP00000410915; ENSG00000235439.
ENST00000431908; ENSP00000408000; ENSG00000198563.
ENST00000446328; ENSP00000414096; ENSG00000215425.
ENST00000448000; ENSP00000411967; ENSG00000225859.
ENST00000452792; ENSP00000398978; ENSG00000229496.
UCSCiuc063nba.1. human.

Organism-specific databases

HGNCiHGNC:13917. DDX39B.
OpenTargetsiENSG00000198563.
ENSG00000215425.
ENSG00000225073.
ENSG00000225859.
ENSG00000229496.
ENSG00000230624.
ENSG00000235439.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00830000128348.

Miscellaneous databases

ChiTaRSiDDX39B. human.

Gene expression databases

BgeeiENSG00000198563.
ExpressionAtlasiF6UJC5. baseline and differential.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF6UJC5_HUMAN
AccessioniPrimary (citable) accession number: F6UJC5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 30, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.