Mos

Functionⁱ

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-KW
protein serine/threonine kinase activity Source: UniProtKB-KW

Keywordsⁱ

Molecular function	Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
Ligand	ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Moloney sarcoma oncogeneImported Submitted name: Proto-oncogene serine/threonine-protein kinase mosImported
Gene namesⁱ	Name:MosImported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 4

Organism-specific databases

MGIⁱ	MGI:97052. Mos.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000078365.

Bgeeⁱ

ENSMUSG00000078365.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	63 – 339	Protein kinaseInterPro annotationAdd BLAST		277

Sequence similaritiesⁱ

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG0192. Eukaryota. COG0515. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118807.
HOVERGENⁱ	HBG052499.
KEGG Orthology (KO) More...KOⁱ	K04367.
OMAⁱ	LAWCSID.
TreeFamⁱ	TF331103.

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_dom. IPR017441. Protein_kinase_ATP_BS. IPR008271. Ser/Thr_kinase_AS.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069. Pkinase. 1 hit.
SMARTⁱ	View protein in SMART SM00220. S_TKc. 1 hit.
SUPFAMⁱ	SSF56112. SSF56112. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

F6UHW1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPSPLSLCRY LPRELSPSVD SRSCSIPLVA PRKAGKLFLG TTPPRAPGLP 
        60         70         80         90        100
RRLAWFSIDW EQVCLMHRLG SGGFGSVYKA TYHGVPVAIK QVNKCTKDLR 
       110        120        130        140        150
ASQRSFWAEL NIARLRHDNI VRVVAASTRT PEDSNSLGTI IMEFGGNVTL 
       160        170        180        190        200
HQVIYGATRS PEPLSCREQL SLGKCLKYSL DVVNGLLFLH SQSILHLDLK 
       210        220        230        240        250
PANILISEQD VCKISDFGCS QKLQDLRCRQ ASPHHIGGTY THQAPEILKG 
       260        270        280        290        300
EIATPKADIY SFGITLWQMT TREVPYSGEP QYVQYAVVAY NLRPSLAGAV 
       310        320        330        340 
FTASLTGKTL QNIIQSCWEA RALQRPGAEL LQRDLKAFRG ALG

Length:343

Mass (Da):37,886

Last modified:November 2, 2016 - v1

Checksum:ⁱ099D3995F2179437

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL807387 Genomic DNA. No translation available. BC137690 mRNA. Translation: AAI37691.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_064405.2. NM_020021.2.
UniGeneⁱ	Mm.459300.

Genome annotation databases

Ensemblⁱ	ENSMUST00000105158; ENSMUSP00000100789; ENSMUSG00000078365.
GeneIDⁱ	17451.
KEGGⁱ	mmu:17451.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL807387 Genomic DNA. No translation available. BC137690 mRNA. Translation: AAI37691.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_064405.2. NM_020021.2.
UniGeneⁱ	Mm.459300.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000105158; ENSMUSP00000100789; ENSMUSG00000078365.
GeneIDⁱ	17451.
KEGGⁱ	mmu:17451.

Organism-specific databases

CTDⁱ	4342.
MGIⁱ	MGI:97052. Mos.

Phylogenomic databases

eggNOGⁱ	KOG0192. Eukaryota. COG0515. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118807.
HOVERGENⁱ	HBG052499.
KEGG Orthology (KO) More...KOⁱ	K04367.
OMAⁱ	LAWCSID.
TreeFamⁱ	TF331103.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000078365.

Bgeeⁱ

ENSMUSG00000078365.

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_dom. IPR017441. Protein_kinase_ATP_BS. IPR008271. Ser/Thr_kinase_AS.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069. Pkinase. 1 hit.
SMARTⁱ	View protein in SMART SM00220. S_TKc. 1 hit.
SUPFAMⁱ	SSF56112. SSF56112. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	F6UHW1_MOUSE
Accessionⁱ	F6UHW1Primary (citable) accession number: F6UHW1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 2, 2016
	Last sequence update:	November 2, 2016
	Last modified:	July 5, 2017
	This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - F6UHW1 (F6UHW1_MOUSE)

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Moloney sarcoma oncogene

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Functionⁱ

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F6UHW1 (F6UHW1_MOUSE)

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Moloney sarcoma oncogene

Mos

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Expressionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ