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Protein
Submitted name:

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Gene

Samhd1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-8956319. Nucleobase catabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1Imported
Gene namesi
Name:Samhd1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1927468. Samhd1.

PTM / Processingi

Proteomic databases

MaxQBiF6TVP2.
PaxDbiF6TVP2.
PRIDEiF6TVP2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000027639.
ExpressionAtlasiF6TVP2. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 122SAMInterPro annotationAdd BLAST66

Phylogenomic databases

eggNOGiKOG2681. Eukaryota.
COG1078. LUCA.
GeneTreeiENSGT00390000013867.

Family and domain databases

CDDicd00077. HDc. 1 hit.
InterProiView protein in InterPro
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR001660. SAM.
IPR013761. SAM/pointed.
PfamiView protein in Pfam
PF01966. HD. 1 hit.
PF07647. SAM_2. 1 hit.
SMARTiView protein in SMART
SM00471. HDc. 1 hit.
SM00454. SAM. 1 hit.
SUPFAMiSSF47769. SSF47769. 1 hit.
PROSITEiView protein in PROSITE
PS50105. SAM_DOMAIN. 1 hit.

Sequencei

Sequence statusi: Fragment.

F6TVP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XTSQPRVSEV AMQSAPLEQP AKRPRCDGSP RTPPSTPPAT ANLSADDDFQ
60 70 80 90 100
NTDLRTWEPE DVCSFLENRG FREKKVLDIF RDNKIAGSFL PFLDEDRLED
110 120 130 140 150
LGVSSLEERK KMIECIQQLS QSRIDLMKVF NDPIHGHIEF HPLLIRIIDT
160 170 180 190 200
PQFQRLRYIK QLGGGYYVFP GASHNRFEHS LGVGYLAGCL VRALAEKQPE
210 220 230 240 250
LQISERDILC VQIAGLCHDL GHGPFSHMFD GRFIPRARPE KKWKHEQGSI
260 270 280 290 300
EMFEHLVNSN ELKLVMKNYG LVPEEDITFI KEQIMGPPIT PVKDSLWPYK
310 320 330 340 350
GRPATKSFLY EIVSNKRNGI DVDKWDYFAR DCHHLGIQNN FDYKRFIKFA
360 370 380 390 400
RICEVEYKVK EDKTYIRKVK HICSREKEVG NLYDMFHTRN CLHRRAYQHK
410 420 430 440 450
ISNLIDIMIT DAFLKADPYV EITGTAGKKF RISTAIDDME AFTKLTDNIF
460 470 480 490 500
LEVLHSTDPQ LSEAQSILRN IECRNLYKYL GETQPKREKI RKEEYERLPQ
510 520 530 540 550
EVAKAKPEKA PDVELKAEDF IVDVINVDYG MEDKNPIDRV HFYCKSNSKQ
560 570 580 590 600
AVRINKEQVS QLLPEKFAEQ LIRVYCKKKD GKSLDAAGKH FVQWCALRDF
610 620 630
TKPQQCGAGE MAEDPDSIPS TQQPHAAHNQ L
Length:631
Mass (Da):72,858
Last modified:July 27, 2011 - v1
Checksum:iE3B40F6C4DDB9639
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669828 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000139263; ENSMUSP00000124935; ENSMUSG00000027639.

Similar proteinsi

Entry informationi

Entry nameiF6TVP2_MOUSE
AccessioniPrimary (citable) accession number: F6TVP2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 27, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported