F6TVK6 (F6TVK6_MONDO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSMODP00000005251

Gene names

Name:

AXIN2 Ensembl ENSMODP00000005251

Organism

Monodelphis domestica (Gray short-tailed opossum) [Reference proteome] Ensembl ENSMODP00000005251

Taxonomic identifier

13616 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Metatheria › Didelphimorphia › Didelphidae › Didelphinae › Monodelphis

Protein attributes

Sequence length	838 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 RGS domain. RuleBase RU003298
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMODP00000005251

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	bone mineralization Inferred from electronic annotation. Source: Compara cell proliferation Inferred from electronic annotation. Source: Compara cellular protein localization Inferred from electronic annotation. Source: Compara chondrocyte differentiation involved in endochondral bone morphogenesis Inferred from electronic annotation. Source: Compara intramembranous ossification Inferred from electronic annotation. Source: Compara mRNA stabilization Inferred from electronic annotation. Source: Compara maintenance of DNA repeat elements Inferred from electronic annotation. Source: Compara negative regulation of canonical Wnt receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of catenin import into nucleus Inferred from electronic annotation. Source: Compara negative regulation of cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of osteoblast differentiation Inferred from electronic annotation. Source: Compara odontogenesis Inferred from electronic annotation. Source: Compara positive regulation of cell death Inferred from electronic annotation. Source: Compara positive regulation of epithelial to mesenchymal transition Inferred from electronic annotation. Source: Compara positive regulation of protein phosphorylation Inferred from electronic annotation. Source: Compara regulation of centromeric sister chromatid cohesion Inferred from electronic annotation. Source: Compara regulation of chondrocyte development Inferred from electronic annotation. Source: Compara regulation of mismatch repair Inferred from electronic annotation. Source: Compara signal transduction Inferred from electronic annotation. Source: GOC somitogenesis Inferred from electronic annotation. Source: Compara termination of G-protein coupled receptor signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular_component	centrosome Inferred from electronic annotation. Source: Compara cytoplasm Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F6TVK6 [UniParc]. Last modified January 9, 2013. Version 2. Checksum: CA1EDC4E6B582D1A	FASTA	838	93,848
	10 20 30 40 50 60 MSSAVLVTHI SDPSSSFRED APRPPVPGEE GETPSCQQSA HLGQGKSLVT KAMPISSNTR 70 80 90 100 110 120 RNEDGLGEPE GRASPDSPLA RWTKSLHSLL GDQDGAYLFR TFLEREQCVD TLDFWFACNG 130 140 150 160 170 180 FRQMNLKDTK TLRVAKAIYK RYIENNCIVS KQLKPATKTY IRDSIKKQQI DSIMFDQAQT 190 200 210 220 230 240 EIQTVMEENA YQMFLTSDIY LEYVRSGGEN PAYINNSGLG SLKVVCGYLP TLNEEEEWSC 250 260 270 280 290 300 EDFKGKILPT VVGLSSKTLR ATANVRSTEA VENGYRSFKR NDPVNPYHVS SGHVFAPAAS 310 320 330 340 350 360 ANDSEISSDA LTDDSMSMTD SSVDGIPPYR MGSKKQLQRE MHRSVKANGQ VSLPHFPRTH 370 380 390 400 410 420 RLPKEMTPIE PAIFAAELIS RLEKLKQEQE SLDNLEERLQ QIKEDEEKEG LELIPVNTRE 430 440 450 460 470 480 LALQHPLSLL PYGSYEEDPQ AILDDHLSRV LKTPGCQSPG MGRHSPRSHS PDHHHHYRPL 490 500 510 520 530 540 LQPGGRLPPP AASSALCPLG KSFVTKQMTK HVYHHYIHHH TIPKTKEQIE VEAAQKVQCF 550 560 570 580 590 600 CLGGTDYYLC SKCKNHSKGV ELGPVEQFGR GNTLSKRNGK VTEPCLALSA KDGGVLVGTG 610 620 630 640 650 660 LLQLPGSEGD RSQNVWQWML ENERQNKHKP HSVQNTKKAY PLESTRGTIT DRPARPHLWG 670 680 690 700 710 720 GNMGHSRAMP HAHPFTQDSG MASLGPPNTL AQLEEACRRL AEVSKPPKQR CCPSNQQKER 730 740 750 760 770 780 NHSVGHLGGV SFCNPNLASE DHREPKKLAS VHSLQASELV VTYFFCGEEI PYRRMLKAQS 790 800 810 820 830 LTLGHFKEQL SKKGNYRYYF KKASDEFDCG AVFEEIWEDD TILPMYEGRI LGKVERID

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences." Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V. , Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M., Samollow P.B., Lander E.S., Lindblad-Toh K. Nature 447:167-177(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
UniGene	Mdm.5180.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMODT00000005364; ENSMODP00000005251; ENSMODG00000004260.
Phylogenomic databases
OMA	NGYRSFK.
Family and domain databases
Gene3D	1.10.196.10. 2 hits.
InterPro	IPR014936. Axin_b-cat-bd. IPR001158. DIX. IPR000342. Regulat_G_prot_signal. IPR024066. Regulat_G_prot_signal_dom1. IPR016137. Regulat_G_prot_signal_superfam. [Graphical view]
Pfam	PF08833. Axin_b-cat_bind. 1 hit. PF00778. DIX. 1 hit. PF00615. RGS. 1 hit. [Graphical view]
PRINTS	PR01301. RGSPROTEIN.
SMART	SM00021. DAX. 1 hit. SM00315. RGS. 1 hit. [Graphical view]
SUPFAM	SSF48097. Regulat_G_prot_signal_superfam. 1 hit.
PROSITE	PS50841. DIX. 1 hit. PS50132. RGS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F6TVK6_MONDO

Accession

Primary (citable) accession number: F6TVK6

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	January 9, 2013
Last modified:	May 1, 2013
This is version 15 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)