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Protein
Submitted name:

Phosphatidylinositol 3-kinase regulatory subunit gamma

Gene

PIK3R3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiF6TDL0.

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 3-kinase regulatory subunit gammaImported
Gene namesi
Name:PIK3R3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiF6TDL0.
PeptideAtlasiF6TDL0.
PRIDEiF6TDL0.

Expressioni

Gene expression databases

BgeeiENSG00000117461.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000262741.

Structurei

3D structure databases

ProteinModelPortaliF6TDL0.
SMRiF6TDL0. Positions 49-501.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini111 – 20696SH2InterPro annotationAdd
BLAST
Domaini404 – 49895SH2InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili227 – 25428Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4637. Eukaryota.
ENOG410XP6R. LUCA.
GeneTreeiENSGT00390000010431.
OMAiTELIFYL.
OrthoDBiEOG091G0C3Z.
PhylomeDBiF6TDL0.

Family and domain databases

Gene3Di3.30.505.10. 2 hits.
InterProiIPR032498. PI3K_P85_iSH2.
IPR001720. PI3kinase_P85.
IPR000980. SH2.
[Graphical view]
PANTHERiPTHR10155. PTHR10155. 1 hit.
PfamiPF16454. PI3K_P85_iSH2. 1 hit.
PF00017. SH2. 2 hits.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
SMARTiSM00252. SH2. 2 hits.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 2 hits.
PROSITEiPS50001. SH2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6TDL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPSRLVRGP RPQGMRSPYR RPGMGWPRPR FPRMFKCSRR RYQQGLRGRT
60 70 80 90 100
ASSAAINPAT RAMGINNTHT DTTIVWIFPP QALPPKPPKP MTSAVPNGMK
110 120 130 140 150
DSSVSLQDAE WYWGDISREE VNDKLRDMPD GTFLVRDAST KMQGDYTLTL
160 170 180 190 200
RKGGNNKLIK IYHRDGKYGF SDPLTFNSVV ELINHYHHES LAQYNPKLDV
210 220 230 240 250
KLMYPVSRYQ QDQLVKEDNI DAVGKKLQEY HSQYQEKSKE YDRLYEEYTR
260 270 280 290 300
TSQEIQMKRT AIEAFNETIK IFEEQCHTQE QHSKEYIERF RREGNEKEIE
310 320 330 340 350
RIMMNYDKLK SRLGEIHDSK MRLEQDLKNQ ALDNREIDKK MNSIKPDLIQ
360 370 380 390 400
LRKIRDQHLV WLNHKGVRQK RLNVWLGIKN EDADENYFIN EEDENLPHYD
410 420 430 440 450
EKTWFVEDIN RVQAEDLLYG KPDGAFLIRE SSKKGCYACS VVADGEVKHC
460 470 480 490 500
VIYSTARGYG FAEPYNLYSS LKELVLHYQQ TSLVQHNDSL NVRLAYPVHA

QMPSLCR
Length:507
Mass (Da):59,394
Last modified:July 27, 2011 - v1
Checksum:i25E8197431435F1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL358075 Genomic DNA. No translation available.
AL672043 Genomic DNA. No translation available.
RefSeqiNP_001290356.1. NM_001303427.1.
UniGeneiHs.655387.

Genome annotation databases

EnsembliENST00000540385; ENSP00000439913; ENSG00000278139.
GeneIDi8503.
UCSCiuc010olw.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL358075 Genomic DNA. No translation available.
AL672043 Genomic DNA. No translation available.
RefSeqiNP_001290356.1. NM_001303427.1.
UniGeneiHs.655387.

3D structure databases

ProteinModelPortaliF6TDL0.
SMRiF6TDL0. Positions 49-501.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000262741.

Proteomic databases

PaxDbiF6TDL0.
PeptideAtlasiF6TDL0.
PRIDEiF6TDL0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000540385; ENSP00000439913; ENSG00000278139.
GeneIDi8503.
UCSCiuc010olw.3. human.

Organism-specific databases

CTDi8503.

Phylogenomic databases

eggNOGiKOG4637. Eukaryota.
ENOG410XP6R. LUCA.
GeneTreeiENSGT00390000010431.
OMAiTELIFYL.
OrthoDBiEOG091G0C3Z.
PhylomeDBiF6TDL0.

Enzyme and pathway databases

SignaLinkiF6TDL0.

Miscellaneous databases

ChiTaRSiPIK3R3. human.
GenomeRNAii8503.

Gene expression databases

BgeeiENSG00000117461.

Family and domain databases

Gene3Di3.30.505.10. 2 hits.
InterProiIPR032498. PI3K_P85_iSH2.
IPR001720. PI3kinase_P85.
IPR000980. SH2.
[Graphical view]
PANTHERiPTHR10155. PTHR10155. 1 hit.
PfamiPF16454. PI3K_P85_iSH2. 1 hit.
PF00017. SH2. 2 hits.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
SMARTiSM00252. SH2. 2 hits.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 2 hits.
PROSITEiPS50001. SH2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF6TDL0_HUMAN
AccessioniPrimary (citable) accession number: F6TDL0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 7, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.