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Protein
Submitted name:

Uncharacterized protein

Gene

LOC110117498-PIK3R3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiF6TDL0.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:LOC110117498-PIK3R3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000278139.1.

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiF6TDL0.
PaxDbiF6TDL0.
PRIDEiF6TDL0.

Expressioni

Gene expression databases

BgeeiENSG00000278139.

Structurei

3D structure databases

ProteinModelPortaliF6TDL0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 206SH2InterPro annotationAdd BLAST96
Domaini404 – 498SH2InterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili227 – 254Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4637. Eukaryota.
ENOG410XP6R. LUCA.
GeneTreeiENSGT00390000010431.
OMAiETYFINE.
OrthoDBiEOG091G0C3Z.
PhylomeDBiF6TDL0.

Family and domain databases

CDDicd09930. SH2_cSH2_p85_like. 1 hit.
cd09942. SH2_nSH2_p85_like. 1 hit.
Gene3Di3.30.505.10. 2 hits.
InterProiView protein in InterPro
IPR032498. PI3K_P85_iSH2.
IPR035020. PI3kinase_P85_cSH2.
IPR035022. PI3kinase_P85_nSH2.
IPR001720. PI3kinase_P85_p55.
IPR000980. SH2.
IPR036860. SH2_dom_sf.
PANTHERiPTHR10155. PTHR10155. 1 hit.
PfamiView protein in Pfam
PF16454. PI3K_P85_iSH2. 1 hit.
PF00017. SH2. 2 hits.
PRINTSiPR00401. SH2DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 2 hits.
SUPFAMiSSF55550. SSF55550. 2 hits.
PROSITEiView protein in PROSITE
PS50001. SH2. 2 hits.

Sequencei

Sequence statusi: Complete.

F6TDL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPSRLVRGP RPQGMRSPYR RPGMGWPRPR FPRMFKCSRR RYQQGLRGRT
60 70 80 90 100
ASSAAINPAT RAMGINNTHT DTTIVWIFPP QALPPKPPKP MTSAVPNGMK
110 120 130 140 150
DSSVSLQDAE WYWGDISREE VNDKLRDMPD GTFLVRDAST KMQGDYTLTL
160 170 180 190 200
RKGGNNKLIK IYHRDGKYGF SDPLTFNSVV ELINHYHHES LAQYNPKLDV
210 220 230 240 250
KLMYPVSRYQ QDQLVKEDNI DAVGKKLQEY HSQYQEKSKE YDRLYEEYTR
260 270 280 290 300
TSQEIQMKRT AIEAFNETIK IFEEQCHTQE QHSKEYIERF RREGNEKEIE
310 320 330 340 350
RIMMNYDKLK SRLGEIHDSK MRLEQDLKNQ ALDNREIDKK MNSIKPDLIQ
360 370 380 390 400
LRKIRDQHLV WLNHKGVRQK RLNVWLGIKN EDADENYFIN EEDENLPHYD
410 420 430 440 450
EKTWFVEDIN RVQAEDLLYG KPDGAFLIRE SSKKGCYACS VVADGEVKHC
460 470 480 490 500
VIYSTARGYG FAEPYNLYSS LKELVLHYQQ TSLVQHNDSL NVRLAYPVHA

QMPSLCR
Length:507
Mass (Da):59,394
Last modified:July 27, 2011 - v1
Checksum:i25E8197431435F1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL358075 Genomic DNA. No translation available.
AL672043 Genomic DNA. No translation available.
RefSeqiNP_001290356.1. NM_001303427.1.
UniGeneiHs.655387.

Genome annotation databases

EnsembliENST00000540385; ENSP00000439913; ENSG00000278139.
GeneIDi110117499.
KEGGihsa:110117499.
UCSCiuc010olw.3. human.

Similar proteinsi

Entry informationi

Entry nameiF6TDL0_HUMAN
AccessioniPrimary (citable) accession number: F6TDL0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: October 25, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported