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F6TCV7 (F6TCV7_MONDO) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length1063 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Membrane; Single-pass type I membrane protein By similarity RuleBase RU003762.

Sequence similarities

Belongs to the integrin alpha chain family. RuleBase RU003762

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMODP00000012596

Ontologies

Keywords
   Biological processCell adhesion RuleBase RU003762 SAAS SAAS013519
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix SAAS SAAS013519
   Molecular functionIntegrin RuleBase RU003762 SAAS SAAS013519
Receptor RuleBase RU003762 SAAS SAAS013519
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcell adhesion

Inferred from electronic annotation. Source: UniProtKB-KW

cell projection organization

Inferred from electronic annotation. Source: Ensembl

establishment of protein localization

Inferred from electronic annotation. Source: Ensembl

extracellular matrix organization

Inferred from electronic annotation. Source: Ensembl

inner ear morphogenesis

Inferred from electronic annotation. Source: Ensembl

integrin-mediated signaling pathway

Inferred from electronic annotation. Source: UniProtKB-KW

memory

Inferred from electronic annotation. Source: Ensembl

metanephros development

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Inferred from electronic annotation. Source: Ensembl

positive regulation of transforming growth factor beta receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

smooth muscle tissue development

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentapical part of cell

Inferred from electronic annotation. Source: Ensembl

integrin complex

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
F6TCV7 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: CD935BF3C52C083C

FASTA1,063117,296
        10         20         30         40         50         60 
MAQGGPRCPA VGSREQLRAP LWGFWTALGM LCSPVSQAFN LDVDKLTVYS GPEGSYFGYA 

        70         80         90        100        110        120 
VDFHIPDQRT VSILVGAPKA NTSQPDIVEG GAVYYCPWPA TGDVHCKQIP FDTTNNRKIR 

       130        140        150        160        170        180 
VNGTKEPIEF KSNQWFGATV KAHKGKVVAC APLYHWRTLK ATREKDPVGT CYVAIQNFSA 

       190        200        210        220        230        240 
YAEYSPCRNS NADPEGQGYC QAGFSLDFYK NGDLIVGGPG SFYWQGQVIT ANIADIIANY 

       250        260        270        280        290        300 
SFKDILRKLT REKQTEVAPA SYDDSYLGYS VAAGEFTGDS QQEILAGVPR GAQNFGYVSI 

       310        320        330        340        350        360 
INSTDMTFIQ NFTGEQMASY FGYALSVSDV NNDGLDDVLV GAPLFMEREF ESSPKEVGQV 

       370        380        390        400        410        420 
YLYLQESPLL FRDAQVLSGT EVFGRFGSAI THLGDLNQDG YNDIAVGAPF AGEAGRGKVF 

       430        440        450        460        470        480 
IYNGNAEGLN QKPSQILNGA WASQAVPSGF GFTLRGDSDI DKNDYPDLIV GAFGTGKVVV 

       490        500        510        520        530        540 
YRARPVVTVD AQLLLHPMII NLENKTCQIP SLATLVPCFT LRVCASVEGQ SISNTVGLIA 

       550        560        570        580        590        600 
DVQLDSLKQK GAIKRTLFRD NHQSQFVFPL VINQYQSLQC QDFIIYLRDE TEFRDKLSPI 

       610        620        630        640        650        660 
NISLNYSLDE STFEEGLAVK PILNFYRESI VNEQAHILVD CGDDNMCIPD LKLSAVPDKE 

       670        680        690        700        710        720 
QLIIGDENHL MLIINARNGG EGAYEAELFV LIPEEADYVG IERNNKALHP LSCEYKMDNV 

       730        740        750        760        770        780 
TRMVVCDLGN PMAAGTNYSL GLRFAVTHLE NTNTSIDFDL QIRSSNKDNP DSNSVSLKIN 

       790        800        810        820        830        840 
VTAVAQVEIR GVSHPPQIVL PIHNWEPEEE PHKEEEVGPL VEHIYELHNI GPSTISETLL 

       850        860        870        880        890        900 
TVGWPNSARE EFLLYIFHIQ TLGPLQCQTN PAINSLGIKP AASQEDTPAL SAFLRNSSIP 

       910        920        930        940        950        960 
HIVRKRHVPV VELHRQSPAK ILNCTNIECL RISCVVGRLE GGESAVLKVR SRLWAQTFLQ 

       970        980        990       1000       1010       1020 
RKNDPYSLAS IVSFEVKKMP YNEQPAQLPK GNVAIRTSVI WATPNVSFSI PLWVIILAIL 

      1030       1040       1050       1060 
LGLLVLTLLT LALWKCGFFD RARPPQDDMA DREQLTNDKV PDA 

« Hide

References

« Hide 'large scale' references
[1]"Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences."
Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V. expand/collapse author list , Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M., Samollow P.B., Lander E.S., Lindblad-Toh K.
Nature 447:167-177(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

RefSeqXP_001377488.1. XM_001377451.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMODT00000012824; ENSMODP00000012596; ENSMODG00000010054.
GeneID100027090.
KEGGmdo:100027090.

Organism-specific databases

CTD8516.

Phylogenomic databases

GeneTreeENSGT00750000117267.
KOK06584.
OMACRQIPFD.
OrthoDBEOG7HQN77.
TreeFamTF105391.

Family and domain databases

InterProIPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
[Graphical view]
PfamPF01839. FG-GAP. 2 hits.
PF00357. Integrin_alpha. 1 hit.
PF08441. Integrin_alpha2. 1 hit.
[Graphical view]
PRINTSPR01185. INTEGRINA.
SMARTSM00191. Int_alpha. 6 hits.
[Graphical view]
PROSITEPS51470. FG_GAP. 7 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF6TCV7_MONDO
AccessionPrimary (citable) accession number: F6TCV7
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 16, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)