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F6TCV7

- F6TCV7_MONDO

UniProt

F6TCV7 - F6TCV7_MONDO

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Protein
Submitted name: Uncharacterized protein
Gene
ITGA8
Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GO - Biological processi

  1. cell adhesion Source: UniProtKB-KW
  2. cell projection organization Source: Ensembl
  3. establishment of protein localization Source: Ensembl
  4. extracellular matrix organization Source: Ensembl
  5. inner ear morphogenesis Source: Ensembl
  6. integrin-mediated signaling pathway Source: UniProtKB-KW
  7. memory Source: Ensembl
  8. metanephros development Source: Ensembl
  9. positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation Source: Ensembl
  10. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  11. smooth muscle tissue development Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

IntegrinUniRule annotationSAAS annotations, ReceptorUniRule annotationSAAS annotations

Keywords - Biological processi

Cell adhesionUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:ITGA8Imported
OrganismiMonodelphis domestica (Gray short-tailed opossum)Imported
Taxonomic identifieri13616 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
ProteomesiUP000002280: Chromosome 8

Subcellular locationi

GO - Cellular componenti

  1. apical part of cell Source: Ensembl
  2. integrin complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the integrin alpha chain family.UniRule annotation
Contains FG-GAP repeats.SAAS annotations

Keywords - Domaini

RepeatSAAS annotations, Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00750000117267.
KOiK06584.
OMAiCRQIPFD.
OrthoDBiEOG7HQN77.
TreeFamiTF105391.

Family and domain databases

InterProiIPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
[Graphical view]
PfamiPF01839. FG-GAP. 2 hits.
PF00357. Integrin_alpha. 1 hit.
PF08441. Integrin_alpha2. 1 hit.
[Graphical view]
PRINTSiPR01185. INTEGRINA.
SMARTiSM00191. Int_alpha. 6 hits.
[Graphical view]
PROSITEiPS51470. FG_GAP. 7 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6TCV7-1 [UniParc]FASTAAdd to Basket

« Hide

MAQGGPRCPA VGSREQLRAP LWGFWTALGM LCSPVSQAFN LDVDKLTVYS     50
GPEGSYFGYA VDFHIPDQRT VSILVGAPKA NTSQPDIVEG GAVYYCPWPA 100
TGDVHCKQIP FDTTNNRKIR VNGTKEPIEF KSNQWFGATV KAHKGKVVAC 150
APLYHWRTLK ATREKDPVGT CYVAIQNFSA YAEYSPCRNS NADPEGQGYC 200
QAGFSLDFYK NGDLIVGGPG SFYWQGQVIT ANIADIIANY SFKDILRKLT 250
REKQTEVAPA SYDDSYLGYS VAAGEFTGDS QQEILAGVPR GAQNFGYVSI 300
INSTDMTFIQ NFTGEQMASY FGYALSVSDV NNDGLDDVLV GAPLFMEREF 350
ESSPKEVGQV YLYLQESPLL FRDAQVLSGT EVFGRFGSAI THLGDLNQDG 400
YNDIAVGAPF AGEAGRGKVF IYNGNAEGLN QKPSQILNGA WASQAVPSGF 450
GFTLRGDSDI DKNDYPDLIV GAFGTGKVVV YRARPVVTVD AQLLLHPMII 500
NLENKTCQIP SLATLVPCFT LRVCASVEGQ SISNTVGLIA DVQLDSLKQK 550
GAIKRTLFRD NHQSQFVFPL VINQYQSLQC QDFIIYLRDE TEFRDKLSPI 600
NISLNYSLDE STFEEGLAVK PILNFYRESI VNEQAHILVD CGDDNMCIPD 650
LKLSAVPDKE QLIIGDENHL MLIINARNGG EGAYEAELFV LIPEEADYVG 700
IERNNKALHP LSCEYKMDNV TRMVVCDLGN PMAAGTNYSL GLRFAVTHLE 750
NTNTSIDFDL QIRSSNKDNP DSNSVSLKIN VTAVAQVEIR GVSHPPQIVL 800
PIHNWEPEEE PHKEEEVGPL VEHIYELHNI GPSTISETLL TVGWPNSARE 850
EFLLYIFHIQ TLGPLQCQTN PAINSLGIKP AASQEDTPAL SAFLRNSSIP 900
HIVRKRHVPV VELHRQSPAK ILNCTNIECL RISCVVGRLE GGESAVLKVR 950
SRLWAQTFLQ RKNDPYSLAS IVSFEVKKMP YNEQPAQLPK GNVAIRTSVI 1000
WATPNVSFSI PLWVIILAIL LGLLVLTLLT LALWKCGFFD RARPPQDDMA 1050
DREQLTNDKV PDA 1063
Length:1,063
Mass (Da):117,296
Last modified:July 27, 2011 - v1
Checksum:iCD935BF3C52C083C
GO

Sequence databases

RefSeqiXP_001377488.1. XM_001377451.2.

Genome annotation databases

EnsembliENSMODT00000012824; ENSMODP00000012596; ENSMODG00000010054.
GeneIDi100027090.
KEGGimdo:100027090.

Cross-referencesi

Sequence databases

RefSeqi XP_001377488.1. XM_001377451.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMODT00000012824 ; ENSMODP00000012596 ; ENSMODG00000010054 .
GeneIDi 100027090.
KEGGi mdo:100027090.

Organism-specific databases

CTDi 8516.

Phylogenomic databases

GeneTreei ENSGT00750000117267.
KOi K06584.
OMAi CRQIPFD.
OrthoDBi EOG7HQN77.
TreeFami TF105391.

Family and domain databases

InterProi IPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
[Graphical view ]
Pfami PF01839. FG-GAP. 2 hits.
PF00357. Integrin_alpha. 1 hit.
PF08441. Integrin_alpha2. 1 hit.
[Graphical view ]
PRINTSi PR01185. INTEGRINA.
SMARTi SM00191. Int_alpha. 6 hits.
[Graphical view ]
PROSITEi PS51470. FG_GAP. 7 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences."
    Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.
    , Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M., Samollow P.B., Lander E.S., Lindblad-Toh K.
    Nature 447:167-177(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF6TCV7_MONDO
AccessioniPrimary (citable) accession number: F6TCV7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 9, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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