Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

F6TCF0

- F6TCF0_HORSE

UniProt

F6TCF0 - F6TCF0_HORSE

Protein
Submitted name:

Uncharacterized protein

Gene

PCSK1

Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. serine-type endopeptidase activity Source: Ensembl

    GO - Biological processi

    1. peptide biosynthetic process Source: Ensembl
    2. peptide hormone processing Source: Ensembl

    Keywords - Molecular functioni

    Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:PCSK1Imported
    OrganismiEquus caballus (Horse)Imported
    Taxonomic identifieri9796 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
    ProteomesiUP000002281: Chromosome 14

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl

    Structurei

    3D structure databases

    ProteinModelPortaliF6TCF0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S8 family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117689.
    KOiK01359.
    OMAiNNPGWKK.
    OrthoDBiEOG7BW0JD.
    TreeFamiTF314277.

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    3.40.50.200. 1 hit.
    InterProiIPR008979. Galactose-bd-like.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR022005. Proho_convert.
    IPR009020. Prot_inh_propept.
    IPR002884. PrprotnconvertsP.
    [Graphical view]
    PANTHERiPTHR10795. PTHR10795. 1 hit.
    PfamiPF01483. P_proprotein. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    PF12177. Proho_convert. 1 hit.
    [Graphical view]
    PRINTSiPR00723. SUBTILISIN.
    SUPFAMiSSF49785. SSF49785. 1 hit.
    SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F6TCF0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERRAWTLQC TAFALFCAWC ALNSVKAKRQ FVNEWAAEIP GGPEAASAIA    50
    EELGYDLLGQ IGSLENHYLF KHKNHPRRSR RSAFHITKRL SDDDRVIWAE 100
    QQYEKERSKR SILRDSALNL FNDPMWNQQW YLQDTRMTAA LPKLDLHVIP 150
    VWQKGITGKG VVITVLDDGL EWNHTDIYDN YDPEASYDFN DNDHDPFPRY 200
    DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE 250
    ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG 300
    SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST 350
    LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP 400
    NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV 450
    DLADPRTWSS VPEKKECVVK DNDFEPRALT ANGEVIIEIP TRACEGQENA 500
    IKSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE RDTSPNGFKN 550
    WDFMSVHTWG ENPIGTWTLR ITDMSGRMQN EGRIVNWKLI LHGTSSQPEH 600
    MKQPRVYTSY NTVQNDRRGV EKMVDSGEEQ PTQENLTTNP LASKSPSGSS 650
    SVGGRRAELA EGAPSEAMLR LLQSAFSKNP AAQQSPKKSP SAKLNIPYEN 700
    FYQALEKLNK PSQLKDSEDS LYNDYVDVFY NTKPYKHRDD RLLQALVDIL 750
    REEN 754
    Length:754
    Mass (Da):84,047
    Last modified:July 27, 2011 - v1
    Checksum:i8DD05AFA8FF579B7
    GO

    Sequence databases

    RefSeqiXP_001504658.1. XM_001504608.3.

    Genome annotation databases

    EnsembliENSECAT00000022083; ENSECAP00000018229; ENSECAG00000020422.
    GeneIDi100064886.
    KEGGiecb:100064886.

    Cross-referencesi

    Sequence databases

    RefSeqi XP_001504658.1. XM_001504608.3.

    3D structure databases

    ProteinModelPortali F6TCF0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSECAT00000022083 ; ENSECAP00000018229 ; ENSECAG00000020422 .
    GeneIDi 100064886.
    KEGGi ecb:100064886.

    Organism-specific databases

    CTDi 5122.

    Phylogenomic databases

    GeneTreei ENSGT00750000117689.
    KOi K01359.
    OMAi NNPGWKK.
    OrthoDBi EOG7BW0JD.
    TreeFami TF314277.

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    3.40.50.200. 1 hit.
    InterProi IPR008979. Galactose-bd-like.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR022005. Proho_convert.
    IPR009020. Prot_inh_propept.
    IPR002884. PrprotnconvertsP.
    [Graphical view ]
    PANTHERi PTHR10795. PTHR10795. 1 hit.
    Pfami PF01483. P_proprotein. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    PF12177. Proho_convert. 1 hit.
    [Graphical view ]
    PRINTSi PR00723. SUBTILISIN.
    SUPFAMi SSF49785. SSF49785. 1 hit.
    SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEi PS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
      Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
      Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
      , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
      Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ThoroughbredImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: ThoroughbredImported.

    Entry informationi

    Entry nameiF6TCF0_HORSE
    AccessioniPrimary (citable) accession number: F6TCF0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3