F6TAA3 (F6TAA3_MONDO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSMODP00000024700

Gene names

Name:

LMX1B Ensembl ENSMODP00000024700

Organism

Monodelphis domestica (Gray short-tailed opossum) [Reference proteome] Ensembl ENSMODP00000024700

Taxonomic identifier

13616 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Metatheria › Didelphimorphia › Didelphidae › Didelphinae › Monodelphis

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU000682.
Sequence similarities	Contains 1 homeobox DNA-binding domain. SAAS SAAS001781 Contains 2 LIM zinc-binding domains. RuleBase RU000350 SAAS SAAS001781
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMODP00000024700

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682 SAAS SAAS001781
Domain	Homeobox RuleBase RU000682 SAAS SAAS001781 LIM domain RuleBase RU000350 SAAS SAAS001781 Repeat SAAS SAAS001781
Ligand	DNA-binding RuleBase RU000682 SAAS SAAS001781 Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell death Inferred from electronic annotation. Source: Compara cell proliferation Inferred from electronic annotation. Source: Compara central nervous system neuron development Inferred from electronic annotation. Source: Compara cerebellum morphogenesis Inferred from electronic annotation. Source: Compara collagen fibril organization Inferred from electronic annotation. Source: Compara dopaminergic neuron differentiation Inferred from electronic annotation. Source: Compara dorsal/ventral pattern formation Inferred from electronic annotation. Source: Compara limb morphogenesis Inferred from electronic annotation. Source: Compara midbrain development Inferred from electronic annotation. Source: Compara neuron migration Inferred from electronic annotation. Source: Compara organ growth Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara trabecular meshwork development Inferred from electronic annotation. Source: Compara
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F6TAA3 [UniParc]. Last modified January 9, 2013. Version 2. Checksum: 7486DC229E3AAB82	FASTA	394	44,043
	10 20 30 40 50 60 MDIATGPESL ERCFPRGQTD CTKMLDGIKM EEHALRPGPA TLGVLLGSDC PHPAVCEGCQ 70 80 90 100 110 120 RPISDRFLMR VNESSWHEEC LQCAACQQAL TTSCYFRDRK LYCKQDYQQL FAAKCSGCME 130 140 150 160 170 180 KIAPTEFVMR ALECVYHLSC FCCCVCERQL RKGDEFVLKE GQLLCKSDYE KEKDLLSSVS 190 200 210 220 230 240 PDESDSVKSD EEDGDVKPAK GQGGQGKGSD DGKDPRRPKR PRTILTTQQR RAFKASFEVS 250 260 270 280 290 300 SKPCRKVRET LAAETGLSVR VVQVWFQNQR AKMKKLARRH QQQQEQQNSQ RLGQEVLSNR 310 320 330 340 350 360 MEGMMASYTP LAPPQQPIVA MEQSTYGSSD PFQQGLTPPQ MPGNDSIFHD IDSDTSLTSL 370 380 390 SDCFLGSSDV GSLQARVGNP IDRLYSMQSS YFAS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences." Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V. , Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M., Samollow P.B., Lander E.S., Lindblad-Toh K. Nature 447:167-177(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
RefSeq	XP_001366137.2. XM_001366100.2.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMODT00000025136; ENSMODP00000024700; ENSMODG00000019789.
GeneID	100016205.
KEGG	mdo:100016205.
Organism-specific databases
CTD	4010.
Phylogenomic databases
KO	K09371.
OMA	NRMEGMM.
Family and domain databases
Gene3D	1.10.10.60. 1 hit. 2.10.110.10. 2 hits.
InterPro	IPR017970. Homeobox_CS. IPR001356. Homeodomain. IPR009057. Homeodomain-like. IPR001781. Znf_LIM. [Graphical view]
Pfam	PF00046. Homeobox. 1 hit. PF00412. LIM. 2 hits. [Graphical view]
SMART	SM00389. HOX. 1 hit. SM00132. LIM. 2 hits. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS00478. LIM_DOMAIN_1. 2 hits. PS50023. LIM_DOMAIN_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F6TAA3_MONDO

Accession

Primary (citable) accession number: F6TAA3

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	January 9, 2013
Last modified:	April 3, 2013
This is version 16 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)