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Protein
Submitted name:

Prostaglandin-endoperoxide synthase 1

Gene

PTGS1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin-endoperoxide synthase 1Imported
Gene namesi
Name:PTGS1Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500895555224 – 598Sequence analysisAdd BLAST575

Expressioni

Gene expression databases

BgeeiENSMMUG00000012886.
ExpressionAtlasiF6S984. baseline.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 68EGF-likeInterPro annotationAdd BLAST39

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2408. Eukaryota.
ENOG410XPZ3. LUCA.
GeneTreeiENSGT00390000010743.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiView protein in InterPro
IPR029580. COX-1.
IPR000742. EGF-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
PANTHERiPTHR11903:SF23. PTHR11903:SF23. 1 hit.
PfamiView protein in Pfam
PF03098. An_peroxidase. 1 hit.
PF00008. EGF. 1 hit.
PRINTSiPR00457. ANPEROXIDASE.
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiView protein in PROSITE
PS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

F6S984-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VSSLLLQFLL LLLLLPQLPV LLADPGAPTP VNPCCYYPCQ HQGICVRFGL
60 70 80 90 100
DRYQCDCTRT GYSGPNCTIP GLWTWLRNSL RPSPSFTHFL LTHGRWFWEF
110 120 130 140 150
VNATFIRELL MRLVLTVRSN LIPSPPTYNS AHDYISWESF SNVSYYTRIL
160 170 180 190 200
PSVPKDCPTP MGTKGKKQLP DAQLLARRFL LRRKFIPDPQ GTNLMFAFFA
210 220 230 240 250
QHFTHQFFKT SGKMGPGFTK ALGHGVDLGH IYGDNLERQY QLRLFKDGKL
260 270 280 290 300
KYQVLDGEVY PPSVEEAPVL MHYPRGTPPQ SQMAVGQEVF GLLPGLMLYA
310 320 330 340 350
TLWLREHNRV CDLLKAEHPT WGDEQLFQTT RLILIGETIR IVIEEYVQQL
360 370 380 390 400
SGYFLQLKFD PELLFGVQFQ YRNRIAMEFN HLYHWHPLMP DSFKVGSQEY
410 420 430 440 450
SYEQFLFNTS MLVDYGVEAL VDAFSRQSAG RIGGGRNMDH HVLHVAVDVI
460 470 480 490 500
RESREMRLQP FNEYRKRFGM KPYTSFQELV GEKEMAAELE ELYGDIDALE
510 520 530 540 550
FYPGLLLEKC HPNSIFGESM IEIGAPFSLK GLLGNPICSP EYWKPSTFGG
560 570 580 590
EMGFNIVKTA TLKKLVCLNT KTCPYVSFRV PDASQDDGPA VERPSTEL
Length:598
Mass (Da):68,395
Last modified:November 30, 2016 - v2
Checksum:i5922BF78BF23E4D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03014299 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMMUT00000018077; ENSMMUP00000016924; ENSMMUG00000012886.

Similar proteinsi

Entry informationi

Entry nameiF6S984_MACMU
AccessioniPrimary (citable) accession number: F6S984
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: November 30, 2016
Last modified: August 30, 2017
This is version 38 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported