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Protein
Submitted name:

Uncharacterized protein

Gene

PTGS1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. peroxidase activity Source: InterPro
  3. prostaglandin-endoperoxide synthase activity Source: Ensembl

GO - Biological processi

  1. cyclooxygenase pathway Source: Ensembl
  2. inflammatory response Source: InterPro
  3. regulation of blood pressure Source: Ensembl
  4. regulation of cell proliferation Source: Ensembl
  5. response to oxidative stress Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PTGS1Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
ProteomesiUP000006718: Chromosome 15

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. photoreceptor outer segment Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiF6S954. baseline.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000010743.
InParanoidiF6S954.
KOiK00509.
OMAiFKTSGKM.
TreeFamiTF329675.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029580. COX-1.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF6. PTHR11903:SF6. 1 hit.
PfamiPF03098. An_peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SMARTiSM00181. EGF. 1 hit.
[Graphical view]
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6S954-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRECDPGAL RGQEVSWPPG GALNARLSRS SLSSAGSLLL QFLLLLLLLP
60 70 80 90 100
QLPVLLADPG APTPVNPCCY YPCQHQGICV RFGLDRYQCD CTRTGYSGPN
110 120 130 140 150
CTIPGLWTWL RNSLRPSPSF THFLLTHGRW FWEFVNATFI RELLMRLVLT
160 170 180 190 200
VRSNLIPSPP TYNSAHDYIS WESFSNVSYY TRILPSVPKD CPTPMGTKGK
210 220 230 240 250
KQLPDAQLLA RRFLLRRKFI PDPQGTNLMF AFFAQHFTHQ FFKTSGKMGP
260 270 280 290 300
GFTKALGHGV DLGHIYGDNL ERQYQLRLFK DGKLKYQVLD GEVYPPSVEE
310 320 330 340 350
APVLMHYPRG TPPQSQMAVG QEVFGLLPGL MLYATLWLRE HNRVCDLLKA
360 370 380 390 400
EHPTWGDEQL FQTTRLILIG ETIRIVIEEY VQQLSGYFLQ LKFDPELLFG
410 420 430 440 450
VQFQYRNRIA MEFNHLYHWH PLMPDSFKVG SQEYSYEQFL FNTSMLVDYG
460 470 480 490 500
VEALVDAFSR QSAGRIGGGR NMDHHVLHVA VDVIRESREM RLQPFNEYRK
510 520 530 540 550
RFGMKPYTSF QELVGEKEMA AELEELYGDI DALEFYPGLL LEKCHPNSIF
560 570 580 590 600
GESMIEIGAP FSLKGLLGNP ICSPEYWKPS TFGGEMGFNI VKTATLKKLV
610 620 630
CLNTKTCPYV SFRVPDASQD DGPAVERPST EL
Length:632
Mass (Da):71,892
Last modified:July 27, 2011 - v1
Checksum:i5BFDA810CBB58F71
GO

Sequence databases

RefSeqiXP_001088157.1. XM_001088157.2.
UniGeneiMmu.23389.

Genome annotation databases

EnsembliENSMMUT00000018079; ENSMMUP00000016926; ENSMMUG00000012886.
GeneIDi698213.
KEGGimcc:698213.

Cross-referencesi

Sequence databases

RefSeqiXP_001088157.1. XM_001088157.2.
UniGeneiMmu.23389.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMMUT00000018079; ENSMMUP00000016926; ENSMMUG00000012886.
GeneIDi698213.
KEGGimcc:698213.

Organism-specific databases

CTDi5742.

Phylogenomic databases

GeneTreeiENSGT00390000010743.
InParanoidiF6S954.
KOiK00509.
OMAiFKTSGKM.
TreeFamiTF329675.

Miscellaneous databases

NextBioi19985585.

Gene expression databases

ExpressionAtlasiF6S954. baseline.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029580. COX-1.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF6. PTHR11903:SF6. 1 hit.
PfamiPF03098. An_peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SMARTiSM00181. EGF. 1 hit.
[Graphical view]
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Evolutionary and biomedical insights from the rhesus macaque genome."
    Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C., Makova K.D., Miller W., Milosavljevic A.
    , Palermo R.E., Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., Zwieg A.S.
    Science 316:222-234(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 17573Imported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: 17573Imported.

Entry informationi

Entry nameiF6S954_MACMU
AccessioniPrimary (citable) accession number: F6S954
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: January 7, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.