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F6RP29

- F6RP29_MOUSE

UniProt

F6RP29 - F6RP29_MOUSE

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Protein
Ribonuclease
Gene
Rnaseh2a
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. RNA-DNA hybrid ribonuclease activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. mismatch repair Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

EndonucleaseUniRule annotation, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
RibonucleaseUniRule annotation (EC:3.1.26.-UniRule annotation)
Gene namesi
Name:Rnaseh2aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 8

Organism-specific databases

MGIiMGI:1916974. Rnaseh2a.

Subcellular locationi

GO - Cellular componenti

  1. ribonuclease H2 complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiF6RP29.
BgeeiF6RP29.

Structurei

3D structure databases

ProteinModelPortaliF6RP29.
SMRiF6RP29. Positions 27-281.

Family & Domainsi

Sequence similaritiesi

Belongs to the RNase HII family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000010768.

Family and domain databases

Gene3Di1.10.10.460. 1 hit.
3.30.420.10. 1 hit.
InterProiIPR004649. RNase_H2_suA.
IPR001352. RNase_HII/HIII.
IPR024567. RNase_HII/HIII_dom.
IPR023160. RNase_HII_hlx-loop-hlx_cap_dom.
IPR012337. RNaseH-like_dom.
[Graphical view]
PANTHERiPTHR10954. PTHR10954. 1 hit.
PfamiPF01351. RNase_HII. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
TIGRFAMsiTIGR00729. TIGR00729. 1 hit.

Sequencei

Sequence statusi: Fragment.

F6RP29-1 [UniParc]FASTAAdd to Basket

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SFRGKRALGP ALAVLFSTIV GCRRGSMDLS ELERDNTGRC RLSSPVPAVC    50
LKEPCVLGVD EAGRGPVLGP MVYAICYCPL SRLADLEALK VADSKTLTEN 100
ERERLFAKME EDGDFVGWAL DVLSPNLIST SMLGRVKYNL NSLSHDTAAG 150
LIQYALDQNV NVTQVFVDTV GMPETYQARL QQHFPGIEVT VKAKADSLFP 200
VVSAASIFAK VARDKAVKNW QFVENLQDLD SDYGSGYPND PKTKAWLRKH 250
VDPVFGFPQF VRFSWSTAQA ILEKEAEDVI WFVS 284
Length:284
Mass (Da):31,370
Last modified:July 27, 2011 - v1
Checksum:i55A8AD85FC4A3AAF
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC163703 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000128972; ENSMUSP00000121864; ENSMUSG00000052926.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC163703 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali F6RP29.
SMRi F6RP29. Positions 27-281.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000128972 ; ENSMUSP00000121864 ; ENSMUSG00000052926 .

Organism-specific databases

MGIi MGI:1916974. Rnaseh2a.

Phylogenomic databases

GeneTreei ENSGT00390000010768.

Miscellaneous databases

ChiTaRSi RNASEH2A. mouse.
NextBioi 35556789.
SOURCEi Search...

Gene expression databases

ArrayExpressi F6RP29.
Bgeei F6RP29.

Family and domain databases

Gene3Di 1.10.10.460. 1 hit.
3.30.420.10. 1 hit.
InterProi IPR004649. RNase_H2_suA.
IPR001352. RNase_HII/HIII.
IPR024567. RNase_HII/HIII_dom.
IPR023160. RNase_HII_hlx-loop-hlx_cap_dom.
IPR012337. RNaseH-like_dom.
[Graphical view ]
PANTHERi PTHR10954. PTHR10954. 1 hit.
Pfami PF01351. RNase_HII. 1 hit.
[Graphical view ]
SUPFAMi SSF53098. SSF53098. 1 hit.
TIGRFAMsi TIGR00729. TIGR00729. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (JUN-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF6RP29_MOUSE
AccessioniPrimary (citable) accession number: F6RP29
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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