Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribonuclease

Gene

Rnaseh2a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotation, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
RibonucleaseUniRule annotation (EC:3.1.26.-UniRule annotation)
Gene namesi
Name:Rnaseh2aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1916974. Rnaseh2a.

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiF6RP29.
PaxDbiF6RP29.
PeptideAtlasiF6RP29.

Expressioni

Gene expression databases

BgeeiENSMUSG00000052926.
ExpressionAtlasiF6RP29. baseline and differential.

Structurei

3D structure databases

SMRiF6RP29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 241RNase_HIIInterPro annotationAdd BLAST211

Sequence similaritiesi

Belongs to the RNase HII family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2299. Eukaryota.
COG0164. LUCA.
GeneTreeiENSGT00390000010768.

Family and domain databases

Gene3Di1.10.10.460. 1 hit.
3.30.420.10. 1 hit.
InterProiView protein in InterPro
IPR004649. RNase_H2_suA.
IPR001352. RNase_HII/HIII.
IPR024567. RNase_HII/HIII_dom.
IPR023160. RNase_HII_hlx-loop-hlx_cap_dom.
IPR012337. RNaseH-like_dom.
PANTHERiPTHR10954. PTHR10954. 1 hit.
PfamiView protein in Pfam
PF01351. RNase_HII. 1 hit.
SUPFAMiSSF53098. SSF53098. 1 hit.
TIGRFAMsiTIGR00729. TIGR00729. 1 hit.

Sequencei

Sequence statusi: Complete.

F6RP29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLSELERDN TGRCRLSSPV PAVCLKEPCV LGVDEAGRGP VLGPMVYAIC
60 70 80 90 100
YCPLSRLADL EALKVADSKT LTENERERLF AKMEEDGDFV GWALDVLSPN
110 120 130 140 150
LISTSMLGRV KYNLNSLSHD TAAGLIQYAL DQNVNVTQVF VDTVGMPETY
160 170 180 190 200
QARLQQHFPG IEVTVKAKAD SLFPVVSAAS IFAKVARDKA VKNWQFVENL
210 220 230 240 250
QDLDSDYGSG YPNDPKTKAW LRKHVDPVFG FPQFVRFSWS TAQAILEKEA

EDVIWFVS
Length:258
Mass (Da):28,668
Last modified:August 30, 2017 - v2
Checksum:i3C51281E32F5679C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC163703 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000128972; ENSMUSP00000121864; ENSMUSG00000052926.

Similar proteinsi

Entry informationi

Entry nameiF6RP29_MOUSE
AccessioniPrimary (citable) accession number: F6RP29
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: August 30, 2017
Last modified: September 27, 2017
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported