Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

F6RP29

- F6RP29_MOUSE

UniProt

F6RP29 - F6RP29_MOUSE

Protein

Ribonuclease

Gene

Rnaseh2a

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

    GO - Molecular functioni

    1. RNA binding Source: InterPro
    2. RNA-DNA hybrid ribonuclease activity Source: InterPro

    GO - Biological processi

    1. mismatch repair Source: MGI

    Keywords - Molecular functioni

    EndonucleaseUniRule annotation, Hydrolase, Nuclease

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RibonucleaseUniRule annotation (EC:3.1.26.-UniRule annotation)
    Gene namesi
    Name:Rnaseh2aImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 8

    Organism-specific databases

    MGIiMGI:1916974. Rnaseh2a.

    Subcellular locationi

    GO - Cellular componenti

    1. ribonuclease H2 complex Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiF6RP29.
    BgeeiF6RP29.

    Structurei

    3D structure databases

    ProteinModelPortaliF6RP29.
    SMRiF6RP29. Positions 27-281.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RNase HII family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00390000010768.

    Family and domain databases

    Gene3Di1.10.10.460. 1 hit.
    3.30.420.10. 1 hit.
    InterProiIPR004649. RNase_H2_suA.
    IPR001352. RNase_HII/HIII.
    IPR024567. RNase_HII/HIII_dom.
    IPR023160. RNase_HII_hlx-loop-hlx_cap_dom.
    IPR012337. RNaseH-like_dom.
    [Graphical view]
    PANTHERiPTHR10954. PTHR10954. 1 hit.
    PfamiPF01351. RNase_HII. 1 hit.
    [Graphical view]
    SUPFAMiSSF53098. SSF53098. 1 hit.
    TIGRFAMsiTIGR00729. TIGR00729. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    F6RP29-1 [UniParc]FASTAAdd to Basket

    « Hide

    SFRGKRALGP ALAVLFSTIV GCRRGSMDLS ELERDNTGRC RLSSPVPAVC    50
    LKEPCVLGVD EAGRGPVLGP MVYAICYCPL SRLADLEALK VADSKTLTEN 100
    ERERLFAKME EDGDFVGWAL DVLSPNLIST SMLGRVKYNL NSLSHDTAAG 150
    LIQYALDQNV NVTQVFVDTV GMPETYQARL QQHFPGIEVT VKAKADSLFP 200
    VVSAASIFAK VARDKAVKNW QFVENLQDLD SDYGSGYPND PKTKAWLRKH 250
    VDPVFGFPQF VRFSWSTAQA ILEKEAEDVI WFVS 284
    Length:284
    Mass (Da):31,370
    Last modified:July 27, 2011 - v1
    Checksum:i55A8AD85FC4A3AAF
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC163703 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000128972; ENSMUSP00000121864; ENSMUSG00000052926.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC163703 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali F6RP29.
    SMRi F6RP29. Positions 27-281.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000128972 ; ENSMUSP00000121864 ; ENSMUSG00000052926 .

    Organism-specific databases

    MGIi MGI:1916974. Rnaseh2a.

    Phylogenomic databases

    GeneTreei ENSGT00390000010768.

    Miscellaneous databases

    ChiTaRSi RNASEH2A. mouse.
    NextBioi 35556789.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi F6RP29.
    Bgeei F6RP29.

    Family and domain databases

    Gene3Di 1.10.10.460. 1 hit.
    3.30.420.10. 1 hit.
    InterProi IPR004649. RNase_H2_suA.
    IPR001352. RNase_HII/HIII.
    IPR024567. RNase_HII/HIII_dom.
    IPR023160. RNase_HII_hlx-loop-hlx_cap_dom.
    IPR012337. RNaseH-like_dom.
    [Graphical view ]
    PANTHERi PTHR10954. PTHR10954. 1 hit.
    Pfami PF01351. RNase_HII. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53098. SSF53098. 1 hit.
    TIGRFAMsi TIGR00729. TIGR00729. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (JUN-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiF6RP29_MOUSE
    AccessioniPrimary (citable) accession number: F6RP29
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3