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Protein
Submitted name:

Collagen alpha-3(IV) chain

Gene

Col4a3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. extracellular matrix structural constituent Source: InterPro
  2. integrin binding Source: MGI

GO - Biological processi

  1. activation of cysteine-type endopeptidase activity involved in apoptotic process Source: MGI
  2. cell proliferation Source: MGI
  3. endothelial cell apoptotic process Source: MGI
  4. negative regulation of angiogenesis Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Collagen alpha-3(IV) chainImported
Gene namesi
Name:Col4a3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:104688. Col4a3.

Subcellular locationi

GO - Cellular componenti

  1. basement membrane Source: MGI
  2. collagen type IV trimer Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiF6RIS8.
ExpressionAtlasiF6RIS8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF6RIS8.
SMRiF6RIS8. Positions 8-150.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00780000121837.

Family and domain databases

Gene3Di2.170.240.10. 1 hit.
InterProiIPR016187. C-type_lectin_fold.
IPR001442. Collagen_VI_NC.
[Graphical view]
PfamiPF01413. C4. 2 hits.
[Graphical view]
SMARTiSM00111. C4. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 2 hits.
PROSITEiPS51403. NC1_IV. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F6RIS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ATGTRMRGFI FTRHSQTTAI PSCPEGTQPL YSGFSLLFVQ GNKRAHGQDL
60 70 80 90 100
GTLGSCLQRF TTMPFLFCNI NNVCNFASRN DYSYWLSTPA LMPMDMAPIS
110 120 130 140 150
GRALEPYISR CTVCEGPAMA IAVHSQTTAI PPCPQDWVSL WKGFSFIMKT
160 170 180 190
YSINCESWRL RENHKPLSGV HEEKTLTKSK KPEPFFFFFF FFLFLLK
Length:197
Mass (Da):22,381
Last modified:July 27, 2011 - v1
Checksum:i0EEA01E6BA6E5AAC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123746 Genomic DNA. No translation available.
AC138214 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000152664; ENSMUSP00000119094; ENSMUSG00000079465.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123746 Genomic DNA. No translation available.
AC138214 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF6RIS8.
SMRiF6RIS8. Positions 8-150.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000152664; ENSMUSP00000119094; ENSMUSG00000079465.

Organism-specific databases

MGIiMGI:104688. Col4a3.

Phylogenomic databases

GeneTreeiENSGT00780000121837.

Miscellaneous databases

ChiTaRSiCol4a3. mouse.
NextBioi35556745.
SOURCEiSearch...

Gene expression databases

BgeeiF6RIS8.
ExpressionAtlasiF6RIS8. baseline and differential.

Family and domain databases

Gene3Di2.170.240.10. 1 hit.
InterProiIPR016187. C-type_lectin_fold.
IPR001442. Collagen_VI_NC.
[Graphical view]
PfamiPF01413. C4. 2 hits.
[Graphical view]
SMARTiSM00111. C4. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 2 hits.
PROSITEiPS51403. NC1_IV. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF6RIS8_MOUSE
AccessioniPrimary (citable) accession number: F6RIS8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: February 4, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.