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Protein
Submitted name:

Destrin

Gene

DSTN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
DestrinImported
Gene namesi
Name:DSTNImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000125868.15.
HGNCiHGNC:15750. DSTN.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000125868.

PTM / Processingi

Proteomic databases

MaxQBiF6RFD5.
PeptideAtlasiF6RFD5.
PRIDEiF6RFD5.

Expressioni

Gene expression databases

BgeeiENSG00000125868.
ExpressionAtlasiF6RFD5. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF6RFD5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 135ADF-HInterPro annotationAdd BLAST132

Sequence similaritiesi

Belongs to the actin-binding proteins ADF family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1735. Eukaryota.
ENOG41122P5. LUCA.
GeneTreeiENSGT00440000033289.

Family and domain databases

CDDicd11286. ADF_cofilin_like. 1 hit.
Gene3Di3.40.20.10. 1 hit.
InterProiView protein in InterPro
IPR002108. ADF-H.
IPR029006. ADF-H/Gelsolin-like_dom_sf.
IPR017904. ADF/Cofilin.
IPR029924. Dstn.
PANTHERiPTHR11913. PTHR11913. 1 hit.
PTHR11913:SF18. PTHR11913:SF18. 1 hit.
PfamiView protein in Pfam
PF00241. Cofilin_ADF. 1 hit.
PRINTSiPR00006. COFILIN.
SMARTiView protein in SMART
SM00102. ADF. 1 hit.
PROSITEiView protein in PROSITE
PS51263. ADF_H. 1 hit.

Sequencei

Sequence statusi: Complete.

F6RFD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGVQVADE VCRIFYDMKV RKCSTPEEIK KRKKAVIFCL SADKKCIIVE
60 70 80 90 100
EGKEILVGDV GVTITDPFKH FVGMLPEKDC RYALYDASFE TKESRKEELM
110 120 130
FFLWAPELAP LKSKMIYASS KDAIKKKFQG KCTHS
Length:135
Mass (Da):15,397
Last modified:July 27, 2011 - v1
Checksum:i3F915CA41419DA8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132765 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000449141; ENSP00000434355; ENSG00000125868.
UCSCiuc061vnz.1. human.

Similar proteinsi

Entry informationi

Entry nameiF6RFD5_HUMAN
AccessioniPrimary (citable) accession number: F6RFD5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported