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F6R9V6

- F6R9V6_MONDO

UniProt

F6R9V6 - F6R9V6_MONDO

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Protein
Submitted name: Uncharacterized protein
Gene
WHSC1
Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. chromatin binding Source: Ensembl
  2. histone-lysine N-methyltransferase activity Source: Ensembl
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. atrial septum primum morphogenesis Source: Ensembl
  2. atrial septum secundum morphogenesis Source: Ensembl
  3. bone development Source: Ensembl
  4. membranous septum morphogenesis Source: Ensembl
  5. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:WHSC1Imported
OrganismiMonodelphis domestica (Gray short-tailed opossum)Imported
Taxonomic identifieri13616 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
ProteomesiUP000002280: Chromosome 5

Subcellular locationi

GO - Cellular componenti

  1. nuclear membrane Source: Ensembl
  2. nucleolus Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotations

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.
Contains 1 post-SET domain.UniRule annotation
Contains SET domain.SAAS annotations
Contains post-SET domain.SAAS annotations

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00740000114921.
OMAiPSKGKMM.
OrthoDBiEOG7Z69BG.
TreeFamiTF329088.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
3.30.40.10. 3 hits.
InterProiIPR006560. AWS.
IPR009071. HMG_box_dom.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00505. HMG_box. 1 hit.
PF00628. PHD. 2 hits.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00398. HMG. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 2 hits.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
SSF57903. SSF57903. 3 hits.
PROSITEiPS51215. AWS. 1 hit.
PS50118. HMG_BOX_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6R9V6-1 [UniParc]FASTAAdd to Basket

« Hide

MNFSIRRNSP SLTQKIVSQL KMKQVPEILG NTNGKTQNCE VNRECSVFLS     50
KAQISTTLPE GVMQKFNGHE ALPFIPAEKL KDLTSRVFNG ESGAQDAKLR 100
FESQEIKGIG TPPHTTPIKN GSPEIKLKIT KTYMNGKPLF ESSICGDNGP 150
DVSQSEENEQ KLENKSRRNR KRSIKYDSLL EQGLVEAALV SKASSPSEKK 200
ILAKRESYPN INKEKDHLLK YNVGDLVWSK VSGYPWWPCM VSADPLLHSY 250
TKLKGQKKSA RQYHVQFFGD APERAWIFEK SLVSFEGEEQ FEKLCQESAK 300
QAPTKAEKIK LLKPISGKLR TQWEMGIIQA KEAVSMTVEE RKAKFTFVYV 350
RDRLHLNPQV AKEAGIAVDP LEEIEESSDM SEETAQNLKH KELGVPIKRR 400
RRSKLLSCTD NLESDSGPKN ITPQRAAEQA DSKRGLGSPV GRKKAAASTP 450
RSRKGDSGSQ FLVFCQKHRD EVVAEHPDAS SEEIEELLES QWNMLNEKQK 500
ARYNTKFAIV TSPKSEEDSG SSLKNIGDTK RKVFQDSPKR RSRSRSNLHG 550
KKRNNTKRTQ HPTEDFEVQE PPRKRLRMDK QNNRKRETSN DKATKTNSSK 600
VTETSSSLKN QSATKNLSDA CKPLKKRNRA SATESSTLAF SKSSSPSTSL 650
TENEISDGQG DEPSESPYES ADETQTEISI SSKKSERGTT AKKEYVCQLC 700
EKSGNLLLCE GPCYGAFHLS CLGLSRRPEG KFICSECTSG IHSCFVCKEK 750
KTEVKRCVVS QCGKFYHEAC VKKYHLTVFE SRGFRCPLHS CVSCHVTNPS 800
NPRSSKGKMM RCVRCPVAYH GGDGCLAAGC SVIASNNIVC TNHFTARKGK 850
SHHAHVNVSW CFVCSKGGSL LCCESCPAAF HPDCLNIEMP DGSWYCNDCR 900
AGKKLHFQDI IWVKLGNYRW WPAEVCHPKN VPPNIQKMKH EIGEFPVFFF 950
GSKDYYWTHQ ARVFPYMEGD RGSRYQGIKG IGKVFKNALH EAEARFREIK 1000
LQREARETQE NERKPPPYKH IKVNKPCGKV QIYTADVSEI PKCNCKPTDE 1050
NPCGFDSECL NRMLMYECHP QVCPAGEQCQ NQCFTKRQYP ETKIIKTDGK 1100
GWGLVAKRDI KKGEFVNEYV GELIDEEECM ARIKYAHEND ITHFYMLTID 1150
KDRIIDAGPK GNYSRFMNHS CQPNCETLKW TVNGDTRVGL FAVCDIPAGT 1200
ELTFNYNLDC LGNEKTVCRC GASNCSGFLG DRPKNSAALS SEEKGKKTKK 1250
KTRRRRTKGE GKKESEDDCF RCGDGGQLVL CDRKCCTKAY HLSCLDLVKR 1300
PFGKWECPWH HCDVCGKPSV SFCHFCPNSF CKEHQDGTVF STTQDGRLCC 1350
SEHDFGVESI RNPKTEKPFP EPTKLKPKRK KRRCWRRKTE CK 1392
Length:1,392
Mass (Da):157,281
Last modified:January 9, 2013 - v2
Checksum:i7253C1785A0473F1
GO

Genome annotation databases

EnsembliENSMODT00000005237; ENSMODP00000005127; ENSMODG00000004162.

Cross-referencesi

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMODT00000005237 ; ENSMODP00000005127 ; ENSMODG00000004162 .

Phylogenomic databases

GeneTreei ENSGT00740000114921.
OMAi PSKGKMM.
OrthoDBi EOG7Z69BG.
TreeFami TF329088.

Family and domain databases

Gene3Di 1.10.30.10. 1 hit.
3.30.40.10. 3 hits.
InterProi IPR006560. AWS.
IPR009071. HMG_box_dom.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF00505. HMG_box. 1 hit.
PF00628. PHD. 2 hits.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00570. AWS. 1 hit.
SM00398. HMG. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 2 hits.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF47095. SSF47095. 1 hit.
SSF57903. SSF57903. 3 hits.
PROSITEi PS51215. AWS. 1 hit.
PS50118. HMG_BOX_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
PS50089. ZF_RING_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences."
    Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.
    , Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M., Samollow P.B., Lander E.S., Lindblad-Toh K.
    Nature 447:167-177(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF6R9V6_MONDO
AccessioniPrimary (citable) accession number: F6R9V6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: January 9, 2013
Last modified: July 9, 2014
This is version 25 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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