F6R9V6 (F6R9V6_MONDO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSMODP00000005127

Gene names

Name:

WHSC1 Ensembl ENSMODP00000005127

Organism

Monodelphis domestica (Gray short-tailed opossum) [Reference proteome] Ensembl ENSMODP00000005127

Taxonomic identifier

13616 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Metatheria › Didelphimorphia › Didelphidae › Didelphinae › Monodelphis

Protein attributes

Sequence length	1392 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214 Contains 1 post-SET domain. RuleBase RU004541 SAAS SAAS001214
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMODP00000005127

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS003616
Domain	Zinc-finger SAAS SAAS001965 RuleBase RU000353
Ligand	Metal-binding Zinc
Molecular function	Methyltransferase SAAS SAAS001214 RuleBase RU004541 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F6R9V6 [UniParc]. Last modified January 9, 2013. Version 2. Checksum: 7253C1785A0473F1	FASTA	1,392	157,281
	10 20 30 40 50 60 MNFSIRRNSP SLTQKIVSQL KMKQVPEILG NTNGKTQNCE VNRECSVFLS KAQISTTLPE 70 80 90 100 110 120 GVMQKFNGHE ALPFIPAEKL KDLTSRVFNG ESGAQDAKLR FESQEIKGIG TPPHTTPIKN 130 140 150 160 170 180 GSPEIKLKIT KTYMNGKPLF ESSICGDNGP DVSQSEENEQ KLENKSRRNR KRSIKYDSLL 190 200 210 220 230 240 EQGLVEAALV SKASSPSEKK ILAKRESYPN INKEKDHLLK YNVGDLVWSK VSGYPWWPCM 250 260 270 280 290 300 VSADPLLHSY TKLKGQKKSA RQYHVQFFGD APERAWIFEK SLVSFEGEEQ FEKLCQESAK 310 320 330 340 350 360 QAPTKAEKIK LLKPISGKLR TQWEMGIIQA KEAVSMTVEE RKAKFTFVYV RDRLHLNPQV 370 380 390 400 410 420 AKEAGIAVDP LEEIEESSDM SEETAQNLKH KELGVPIKRR RRSKLLSCTD NLESDSGPKN 430 440 450 460 470 480 ITPQRAAEQA DSKRGLGSPV GRKKAAASTP RSRKGDSGSQ FLVFCQKHRD EVVAEHPDAS 490 500 510 520 530 540 SEEIEELLES QWNMLNEKQK ARYNTKFAIV TSPKSEEDSG SSLKNIGDTK RKVFQDSPKR 550 560 570 580 590 600 RSRSRSNLHG KKRNNTKRTQ HPTEDFEVQE PPRKRLRMDK QNNRKRETSN DKATKTNSSK 610 620 630 640 650 660 VTETSSSLKN QSATKNLSDA CKPLKKRNRA SATESSTLAF SKSSSPSTSL TENEISDGQG 670 680 690 700 710 720 DEPSESPYES ADETQTEISI SSKKSERGTT AKKEYVCQLC EKSGNLLLCE GPCYGAFHLS 730 740 750 760 770 780 CLGLSRRPEG KFICSECTSG IHSCFVCKEK KTEVKRCVVS QCGKFYHEAC VKKYHLTVFE 790 800 810 820 830 840 SRGFRCPLHS CVSCHVTNPS NPRSSKGKMM RCVRCPVAYH GGDGCLAAGC SVIASNNIVC 850 860 870 880 890 900 TNHFTARKGK SHHAHVNVSW CFVCSKGGSL LCCESCPAAF HPDCLNIEMP DGSWYCNDCR 910 920 930 940 950 960 AGKKLHFQDI IWVKLGNYRW WPAEVCHPKN VPPNIQKMKH EIGEFPVFFF GSKDYYWTHQ 970 980 990 1000 1010 1020 ARVFPYMEGD RGSRYQGIKG IGKVFKNALH EAEARFREIK LQREARETQE NERKPPPYKH 1030 1040 1050 1060 1070 1080 IKVNKPCGKV QIYTADVSEI PKCNCKPTDE NPCGFDSECL NRMLMYECHP QVCPAGEQCQ 1090 1100 1110 1120 1130 1140 NQCFTKRQYP ETKIIKTDGK GWGLVAKRDI KKGEFVNEYV GELIDEEECM ARIKYAHEND 1150 1160 1170 1180 1190 1200 ITHFYMLTID KDRIIDAGPK GNYSRFMNHS CQPNCETLKW TVNGDTRVGL FAVCDIPAGT 1210 1220 1230 1240 1250 1260 ELTFNYNLDC LGNEKTVCRC GASNCSGFLG DRPKNSAALS SEEKGKKTKK KTRRRRTKGE 1270 1280 1290 1300 1310 1320 GKKESEDDCF RCGDGGQLVL CDRKCCTKAY HLSCLDLVKR PFGKWECPWH HCDVCGKPSV 1330 1340 1350 1360 1370 1380 SFCHFCPNSF CKEHQDGTVF STTQDGRLCC SEHDFGVESI RNPKTEKPFP EPTKLKPKRK 1390 KRRCWRRKTE CK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences." Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V. , Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M., Samollow P.B., Lander E.S., Lindblad-Toh K. Nature 447:167-177(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMODT00000005237; ENSMODP00000005127; ENSMODG00000004162.
Family and domain databases
Gene3D	1.10.30.10. 1 hit. 3.30.40.10. 3 hits.
InterPro	IPR006560. AWS. IPR009071. HMG_box_dom. IPR003616. Post-SET_dom. IPR000313. PWWP. IPR001214. SET_dom. IPR019786. Zinc_finger_PHD-type_CS. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR019787. Znf_PHD-finger. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Pfam	PF00505. HMG_box. 1 hit. PF00628. PHD. 2 hits. PF00855. PWWP. 2 hits. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00570. AWS. 1 hit. SM00398. HMG. 1 hit. SM00249. PHD. 4 hits. SM00508. PostSET. 1 hit. SM00293. PWWP. 2 hits. SM00184. RING. 2 hits. SM00317. SET. 1 hit. [Graphical view]
SUPFAM	SSF57903. FYVE_PHD_ZnF. 3 hits. SSF47095. HMG-box. 1 hit.
PROSITE	PS51215. AWS. 1 hit. PS50118. HMG_BOX_2. 1 hit. PS50868. POST_SET. 1 hit. PS50812. PWWP. 2 hits. PS50280. SET. 1 hit. PS01359. ZF_PHD_1. 2 hits. PS50016. ZF_PHD_2. 2 hits. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F6R9V6_MONDO

Accession

Primary (citable) accession number: F6R9V6

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	January 9, 2013
Last modified:	May 1, 2013
This is version 17 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)