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F6PW39

- F6PW39_HORSE

UniProt

F6PW39 - F6PW39_HORSE

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Protein
Submitted name: Uncharacterized protein
Gene
TGM1
Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei381 – 3811 By similarityUniRule annotation
Active sitei440 – 4401 By similarityUniRule annotation
Active sitei463 – 4631 By similarityUniRule annotation
Metal bindingi503 – 5031Calcium By similarityUniRule annotation
Metal bindingi505 – 5051Calcium By similarityUniRule annotation
Metal bindingi552 – 5521Calcium By similarityUniRule annotation
Metal bindingi557 – 5571Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. keratinocyte differentiation Source: Ensembl
  2. organ morphogenesis Source: Ensembl
  3. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM1Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
ProteomesiUP000002281: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. cell-cell adherens junction Source: Ensembl
  2. intrinsic component of membrane Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115156.
KOiK05619.
OMAiGRWGGNP.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6PW39-1 [UniParc]FASTAAdd to Basket

« Hide

MTDGPRSDVG RWGGNAWQPP TTPSPEPEPE PEPDSRSRRG GRSFWARCCG    50
CCSCRNDDDW GREPYRDRGS GSRGRGSRSG GRRPDSRGSD SRQPGSRGSG 100
VNAAGDGTIR EGMLVVTGVD LLSSRSDQNR REHHTDEFEY DELIVRRGQP 150
FHMVLLLSRP YESSDHIALE LLIGNNPEVG KGTHVIIPVG KGGSGGWKAQ 200
VTKANGQNLN LRVHTSPNAI IGKFQFTVRT RTEAGEFQLP FDPHNEIYIL 250
FNPWCPEDIV YVDHEDWRQE YVLNESGRIY YGTEAQIGER TWNYGQFDHG 300
VLDACLYILD RRGMPYGGRG DPVNVSRVIS AMVNSLDDNG VLIGNWSGDY 350
SRGTNPSAWV GSVEILLSYL RTGYSVPYGQ CWVFAGVTTT VLRCLGLATR 400
TVTNFNSAHD TDTSLTMDIY FDENMKPLEH LNHDSVWNFH VWNDCWMKRP 450
DLPSGFDGWQ VVDATPQETS SGIFCCGPCS VESIKNGLVY MKYDTPFIFA 500
EVNSDKVYWQ RQDDGSFKIV YVEEKAIGTL IITKAIGSSM REDVTHIYKH 550
PEGSEAERKA VETAAAHGSK PNVYANRDTA EDVAMQVEAQ DAVMGQDLTV 600
SVVLTNRGSS RRTVKLHLYL SVTFYTGVTG SVFKESKKEV VLQPGASDRV 650
AMPVAYTEYK PHLVDQGAML LNVSGHVKES GQVLAKQHTF RLRTPDLSLS 700
LLGAAVVGQE CEVQIVFKNP LPVTLTNVVF RLEGSGLQRP KILNVGDIGG 750
NETVTLRQTF VPVRPGPRQL IASLDSPQLS QVHGVIQVDV APAPGGGSFF 800
SDARGNSRSG ETIPMASRGG A 821
Length:821
Mass (Da):90,387
Last modified:July 27, 2011 - v1
Checksum:i7912B3E509F98BA7
GO

Sequence databases

RefSeqiXP_001489215.1. XM_001489165.2.

Genome annotation databases

EnsembliENSECAT00000018986; ENSECAP00000015519; ENSECAG00000017485.
GeneIDi100054584.
KEGGiecb:100054584.

Cross-referencesi

Sequence databases

RefSeqi XP_001489215.1. XM_001489165.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSECAT00000018986 ; ENSECAP00000015519 ; ENSECAG00000017485 .
GeneIDi 100054584.
KEGGi ecb:100054584.

Organism-specific databases

CTDi 7051.

Phylogenomic databases

GeneTreei ENSGT00740000115156.
KOi K05619.
OMAi GRWGGNP.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
    Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
    Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
    , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
    Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThoroughbredImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThoroughbredImported.

Entry informationi

Entry nameiF6PW39_HORSE
AccessioniPrimary (citable) accession number: F6PW39
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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