F6PW39 (F6PW39_HORSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSECAP00000015519

Gene names

Name:

TGM1 Ensembl ENSECAP00000015519

Organism

Equus caballus (Horse) [Reference proteome] Ensembl ENSECAP00000015519

Taxonomic identifier

9796 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › Equus

Protein attributes

Sequence length	821 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSECAP00000015519

Ontologies

Keywords
Ligand	Calcium PIRSR PIRSR000459-2 Metal-binding PIRSR PIRSR000459-2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	keratinocyte differentiation Inferred from electronic annotation. Source: Compara organ morphogenesis Inferred from electronic annotation. Source: Compara peptide cross-linking Inferred from electronic annotation. Source: InterPro
Cellular_component	cell-cell adherens junction Inferred from electronic annotation. Source: Compara intrinsic to membrane Inferred from electronic annotation. Source: Compara
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	381	1	By similarity PIRSR PIRSR000459-1
	Active site	440	1	By similarity PIRSR PIRSR000459-1
	Active site	463	1	By similarity PIRSR PIRSR000459-1
	Metal binding	503	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	505	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	552	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	557	1	Calcium By similarity PIRSR PIRSR000459-2

Sequences

	Sequence		Length	Mass (Da)
	F6PW39 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: 7912B3E509F98BA7	FASTA	821	90,387
	10 20 30 40 50 60 MTDGPRSDVG RWGGNAWQPP TTPSPEPEPE PEPDSRSRRG GRSFWARCCG CCSCRNDDDW 70 80 90 100 110 120 GREPYRDRGS GSRGRGSRSG GRRPDSRGSD SRQPGSRGSG VNAAGDGTIR EGMLVVTGVD 130 140 150 160 170 180 LLSSRSDQNR REHHTDEFEY DELIVRRGQP FHMVLLLSRP YESSDHIALE LLIGNNPEVG 190 200 210 220 230 240 KGTHVIIPVG KGGSGGWKAQ VTKANGQNLN LRVHTSPNAI IGKFQFTVRT RTEAGEFQLP 250 260 270 280 290 300 FDPHNEIYIL FNPWCPEDIV YVDHEDWRQE YVLNESGRIY YGTEAQIGER TWNYGQFDHG 310 320 330 340 350 360 VLDACLYILD RRGMPYGGRG DPVNVSRVIS AMVNSLDDNG VLIGNWSGDY SRGTNPSAWV 370 380 390 400 410 420 GSVEILLSYL RTGYSVPYGQ CWVFAGVTTT VLRCLGLATR TVTNFNSAHD TDTSLTMDIY 430 440 450 460 470 480 FDENMKPLEH LNHDSVWNFH VWNDCWMKRP DLPSGFDGWQ VVDATPQETS SGIFCCGPCS 490 500 510 520 530 540 VESIKNGLVY MKYDTPFIFA EVNSDKVYWQ RQDDGSFKIV YVEEKAIGTL IITKAIGSSM 550 560 570 580 590 600 REDVTHIYKH PEGSEAERKA VETAAAHGSK PNVYANRDTA EDVAMQVEAQ DAVMGQDLTV 610 620 630 640 650 660 SVVLTNRGSS RRTVKLHLYL SVTFYTGVTG SVFKESKKEV VLQPGASDRV AMPVAYTEYK 670 680 690 700 710 720 PHLVDQGAML LNVSGHVKES GQVLAKQHTF RLRTPDLSLS LLGAAVVGQE CEVQIVFKNP 730 740 750 760 770 780 LPVTLTNVVF RLEGSGLQRP KILNVGDIGG NETVTLRQTF VPVRPGPRQL IASLDSPQLS 790 800 810 820 QVHGVIQVDV APAPGGGSFF SDARGNSRSG ETIPMASRGG A

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence, comparative analysis, and population genetics of the domestic horse." Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T. , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K. Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Thoroughbred Ensembl ENSECAP00000015519.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Thoroughbred Ensembl ENSECAP00000015519.

Cross-references

Sequence databases
RefSeq	XP_001489215.1. XM_001489165.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSECAT00000018986; ENSECAP00000015519; ENSECAG00000017485.
GeneID	100054584.
KEGG	ecb:100054584.
Phylogenomic databases
GeneTree	ENSGT00690000101887.
KO	K05619.
OMA	GRWGGNP.
Family and domain databases
Gene3D	2.60.40.10. 3 hits.
InterPro	IPR023608. Gln_gamma-glutamylTfrase_euk. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002931. Transglutaminase-like. IPR008958. Transglutaminase_C. IPR013808. Transglutaminase_CS. IPR001102. Transglutaminase_N. [Graphical view]
PANTHER	PTHR11590. PTHR11590. 1 hit.
Pfam	PF00927. Transglut_C. 2 hits. PF01841. Transglut_core. 1 hit. PF00868. Transglut_N. 1 hit. [Graphical view]
PIRSF	PIRSF000459. TGM_EBP42. 1 hit.
SMART	SM00460. TGc. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49309. Transglut_C. 2 hits.
PROSITE	PS00547. TRANSGLUTAMINASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F6PW39_HORSE

Accession

Primary (citable) accession number: F6PW39

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	March 6, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)