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F6PW39

- F6PW39_HORSE

UniProt

F6PW39 - F6PW39_HORSE

Protein
Submitted name:

Uncharacterized protein

Gene

TGM1

Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei381 – 3811UniRule annotation
    Active sitei440 – 4401UniRule annotation
    Active sitei463 – 4631UniRule annotation
    Metal bindingi503 – 5031Calcium
    Metal bindingi505 – 5051Calcium
    Metal bindingi552 – 5521Calcium
    Metal bindingi557 – 5571Calcium

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

    GO - Biological processi

    1. keratinocyte differentiation Source: Ensembl
    2. organ morphogenesis Source: Ensembl
    3. peptide cross-linking Source: InterPro

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:TGM1Imported
    OrganismiEquus caballus (Horse)Imported
    Taxonomic identifieri9796 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
    ProteomesiUP000002281: Chromosome 1

    Subcellular locationi

    GO - Cellular componenti

    1. cell-cell adherens junction Source: Ensembl
    2. intrinsic component of membrane Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115156.
    KOiK05619.
    OMAiGRWGGNP.
    OrthoDBiEOG7WT40M.
    TreeFamiTF324278.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F6PW39-1 [UniParc]FASTAAdd to Basket

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    MTDGPRSDVG RWGGNAWQPP TTPSPEPEPE PEPDSRSRRG GRSFWARCCG    50
    CCSCRNDDDW GREPYRDRGS GSRGRGSRSG GRRPDSRGSD SRQPGSRGSG 100
    VNAAGDGTIR EGMLVVTGVD LLSSRSDQNR REHHTDEFEY DELIVRRGQP 150
    FHMVLLLSRP YESSDHIALE LLIGNNPEVG KGTHVIIPVG KGGSGGWKAQ 200
    VTKANGQNLN LRVHTSPNAI IGKFQFTVRT RTEAGEFQLP FDPHNEIYIL 250
    FNPWCPEDIV YVDHEDWRQE YVLNESGRIY YGTEAQIGER TWNYGQFDHG 300
    VLDACLYILD RRGMPYGGRG DPVNVSRVIS AMVNSLDDNG VLIGNWSGDY 350
    SRGTNPSAWV GSVEILLSYL RTGYSVPYGQ CWVFAGVTTT VLRCLGLATR 400
    TVTNFNSAHD TDTSLTMDIY FDENMKPLEH LNHDSVWNFH VWNDCWMKRP 450
    DLPSGFDGWQ VVDATPQETS SGIFCCGPCS VESIKNGLVY MKYDTPFIFA 500
    EVNSDKVYWQ RQDDGSFKIV YVEEKAIGTL IITKAIGSSM REDVTHIYKH 550
    PEGSEAERKA VETAAAHGSK PNVYANRDTA EDVAMQVEAQ DAVMGQDLTV 600
    SVVLTNRGSS RRTVKLHLYL SVTFYTGVTG SVFKESKKEV VLQPGASDRV 650
    AMPVAYTEYK PHLVDQGAML LNVSGHVKES GQVLAKQHTF RLRTPDLSLS 700
    LLGAAVVGQE CEVQIVFKNP LPVTLTNVVF RLEGSGLQRP KILNVGDIGG 750
    NETVTLRQTF VPVRPGPRQL IASLDSPQLS QVHGVIQVDV APAPGGGSFF 800
    SDARGNSRSG ETIPMASRGG A 821
    Length:821
    Mass (Da):90,387
    Last modified:July 27, 2011 - v1
    Checksum:i7912B3E509F98BA7
    GO

    Sequence databases

    RefSeqiXP_001489215.1. XM_001489165.2.

    Genome annotation databases

    EnsembliENSECAT00000018986; ENSECAP00000015519; ENSECAG00000017485.
    GeneIDi100054584.
    KEGGiecb:100054584.

    Cross-referencesi

    Sequence databases

    RefSeqi XP_001489215.1. XM_001489165.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSECAT00000018986 ; ENSECAP00000015519 ; ENSECAG00000017485 .
    GeneIDi 100054584.
    KEGGi ecb:100054584.

    Organism-specific databases

    CTDi 7051.

    Phylogenomic databases

    GeneTreei ENSGT00740000115156.
    KOi K05619.
    OMAi GRWGGNP.
    OrthoDBi EOG7WT40M.
    TreeFami TF324278.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
      Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
      Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
      , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
      Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ThoroughbredImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: ThoroughbredImported.

    Entry informationi

    Entry nameiF6PW39_HORSE
    AccessioniPrimary (citable) accession number: F6PW39
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3