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F6PW39

- F6PW39_HORSE

UniProt

F6PW39 - F6PW39_HORSE

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Protein
Submitted name:

Uncharacterized protein

Gene

TGM1

Organism
Equus caballus (Horse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei381 – 3811UniRule annotation
Active sitei440 – 4401UniRule annotation
Active sitei463 – 4631UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. keratinocyte differentiation Source: Ensembl
  2. organ morphogenesis Source: Ensembl
  3. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM1Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
ProteomesiUP000002281: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. cell-cell adherens junction Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. intrinsic component of membrane Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
InParanoidiF6PW39.
KOiK05619.
OMAiGRWGGNP.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6PW39-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTDGPRSDVG RWGGNAWQPP TTPSPEPEPE PEPDSRSRRG GRSFWARCCG
60 70 80 90 100
CCSCRNDDDW GREPYRDRGS GSRGRGSRSG GRRPDSRGSD SRQPGSRGSG
110 120 130 140 150
VNAAGDGTIR EGMLVVTGVD LLSSRSDQNR REHHTDEFEY DELIVRRGQP
160 170 180 190 200
FHMVLLLSRP YESSDHIALE LLIGNNPEVG KGTHVIIPVG KGGSGGWKAQ
210 220 230 240 250
VTKANGQNLN LRVHTSPNAI IGKFQFTVRT RTEAGEFQLP FDPHNEIYIL
260 270 280 290 300
FNPWCPEDIV YVDHEDWRQE YVLNESGRIY YGTEAQIGER TWNYGQFDHG
310 320 330 340 350
VLDACLYILD RRGMPYGGRG DPVNVSRVIS AMVNSLDDNG VLIGNWSGDY
360 370 380 390 400
SRGTNPSAWV GSVEILLSYL RTGYSVPYGQ CWVFAGVTTT VLRCLGLATR
410 420 430 440 450
TVTNFNSAHD TDTSLTMDIY FDENMKPLEH LNHDSVWNFH VWNDCWMKRP
460 470 480 490 500
DLPSGFDGWQ VVDATPQETS SGIFCCGPCS VESIKNGLVY MKYDTPFIFA
510 520 530 540 550
EVNSDKVYWQ RQDDGSFKIV YVEEKAIGTL IITKAIGSSM REDVTHIYKH
560 570 580 590 600
PEGSEAERKA VETAAAHGSK PNVYANRDTA EDVAMQVEAQ DAVMGQDLTV
610 620 630 640 650
SVVLTNRGSS RRTVKLHLYL SVTFYTGVTG SVFKESKKEV VLQPGASDRV
660 670 680 690 700
AMPVAYTEYK PHLVDQGAML LNVSGHVKES GQVLAKQHTF RLRTPDLSLS
710 720 730 740 750
LLGAAVVGQE CEVQIVFKNP LPVTLTNVVF RLEGSGLQRP KILNVGDIGG
760 770 780 790 800
NETVTLRQTF VPVRPGPRQL IASLDSPQLS QVHGVIQVDV APAPGGGSFF
810 820
SDARGNSRSG ETIPMASRGG A
Length:821
Mass (Da):90,387
Last modified:July 27, 2011 - v1
Checksum:i7912B3E509F98BA7
GO

Sequence databases

RefSeqiXP_001489215.1. XM_001489165.2.

Genome annotation databases

EnsembliENSECAT00000018986; ENSECAP00000015519; ENSECAG00000017485.
GeneIDi100054584.
KEGGiecb:100054584.

Cross-referencesi

Sequence databases

RefSeqi XP_001489215.1. XM_001489165.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSECAT00000018986 ; ENSECAP00000015519 ; ENSECAG00000017485 .
GeneIDi 100054584.
KEGGi ecb:100054584.

Organism-specific databases

CTDi 7051.

Phylogenomic databases

GeneTreei ENSGT00760000119108.
InParanoidi F6PW39.
KOi K05619.
OMAi GRWGGNP.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence, comparative analysis, and population genetics of the domestic horse."
    Broad Institute Genome Sequencing Platform, Broad Institute Whole Genome Assembly Team
    Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.
    , Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.
    Science 326:865-867(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThoroughbredImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThoroughbredImported.

Entry informationi

Entry nameiF6PW39_HORSE
AccessioniPrimary (citable) accession number: F6PW39
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 26, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3