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Protein
Submitted name:

Synuclein alpha-140

Gene

NACP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Synuclein alpha-140Imported
Gene namesi
Name:NACPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiF6L6N6.
PRIDEiF6L6N6.

Expressioni

Gene expression databases

BgeeiF6L6N6.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000338345.

Chemistry

BindingDBiF6L6N6.

Family & Domainsi

Sequence similaritiesi

Belongs to the synuclein family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IWI2. Eukaryota.
ENOG4111TDZ. LUCA.

Family and domain databases

Gene3Di1.10.287.700. 1 hit.
InterProiIPR001058. Synuclein.
IPR002460. Synuclein_alpha.
[Graphical view]
PANTHERiPTHR13820. PTHR13820. 1 hit.
PTHR13820:SF5. PTHR13820:SF5. 1 hit.
PfamiPF01387. Synuclein. 1 hit.
[Graphical view]
PRINTSiPR01211. SYNUCLEIN.

Sequencei

Sequence statusi: Fragment.

F6L6N6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH
60 70
GVATVAEKTK EQVTNVGGAV VTGVTAVAQ
Length:79
Mass (Da):7,931
Last modified:July 27, 2011 - v1
Checksum:i48F7584FEA865FD2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei79 – 791Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ830267 mRNA. Translation: AEG20815.1.
HQ830268 mRNA. Translation: AEG20816.1.
HQ830269 mRNA. Translation: AEG20817.1.
UniGeneiHs.21374.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ830267 mRNA. Translation: AEG20815.1.
HQ830268 mRNA. Translation: AEG20816.1.
HQ830269 mRNA. Translation: AEG20817.1.
UniGeneiHs.21374.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000338345.

Chemistry

BindingDBiF6L6N6.

Proteomic databases

PaxDbiF6L6N6.
PRIDEiF6L6N6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IWI2. Eukaryota.
ENOG4111TDZ. LUCA.

Miscellaneous databases

ChiTaRSiSNCA. human.
NextBioi35510173.

Gene expression databases

BgeeiF6L6N6.

Family and domain databases

Gene3Di1.10.287.700. 1 hit.
InterProiIPR001058. Synuclein.
IPR002460. Synuclein_alpha.
[Graphical view]
PANTHERiPTHR13820. PTHR13820. 1 hit.
PTHR13820:SF5. PTHR13820:SF5. 1 hit.
PfamiPF01387. Synuclein. 1 hit.
[Graphical view]
PRINTSiPR01211. SYNUCLEIN.
ProtoNetiSearch...

Publicationsi

  1. "Pro-inflammatory stimuli modulate alpha-synuclein expression in human monocyte-derived dendritic cells: role of a novel exon 1 splice variant."
    Baltic S., Thompson P.J., Misso N.L., Fogel-Petrovic M.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiF6L6N6_HUMAN
AccessioniPrimary (citable) accession number: F6L6N6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: May 11, 2016
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.