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F6IJ61 (F6IJ61_9SPHN) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
ORF Names:PP1Y_AT7490 EMBL CCA91687.1
OrganismNovosphingobium sp. PP1Y [Complete proteome] EMBL CCA91687.1
Taxonomic identifier702113 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeNovosphingobium

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain125 – 325201ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding152 – 20857ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2761Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2921Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2921Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2941Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
F6IJ61 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 10E1047439B4C474

FASTA34437,049
        10         20         30         40         50         60 
MGNPARRHAC RRAQHTASRY TVSLPKLHVA VLMGGWSHER SVSLMSGEGV AKALESKGHK 

        70         80         90        100        110        120 
VTRIDMDRNV ALRLSEAAPD VVFNALHGAP GEDGTVQGMM DLMGLTYTHS GLATSVIAID 

       130        140        150        160        170        180 
KELTKQALVP HGIPMPGGRI VASEDLYAGD PLPRPYVLKP VNEGSSVGVA IVMDASNYGN 

       190        200        210        220        230        240 
PIRRDAAGPW QEFDHLLAEP YIRGRELTTA VIGDRALLVT ELKPKSGFYD FDSKYTDGLT 

       250        260        270        280        290        300 
EHVCPAEIPD EIAQACKDLA LRAHRLLGCK GTSRSDFRWD DTQGVEGLFL LETNTQPGMT 

       310        320        330        340 
PLSLVPEQAR ACGMEYADLV EAIIAEALED ARSKQAAGAV KGAE 

« Hide

References

[1]"De Novo Sequencing and Assembly of the Whole Genome of Novosphingobium sp. Strain PP1Y."
D'Argenio V., Petrillo M., Cantiello P., Naso B., Cozzuto L., Notomista E., Paolella G., Di Donato A., Salvatore F.
J. Bacteriol. 193:4296-4296(2011)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: PP1Y EMBL CCA91687.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FR856862 Genomic DNA. Translation: CCA91687.1.
RefSeqYP_004533505.1. NC_015580.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCA91687; CCA91687; PP1Y_AT7490.
GeneID10717485.
KEGGnpp:PP1Y_AT7490.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycNSP702113:GJD2-718-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF6IJ61_9SPHN
AccessionPrimary (citable) accession number: F6IJ61
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: February 19, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)