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F6G4U4 (F6G4U4_RALS8) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Kynureninase PIRNR PIRNR038800
EC=3.7.1.3 PIRNR PIRNR038800
Gene names
Name:kynU EMBL AEG69899.1
Ordered Locus Names:RSPO_c02606 EMBL AEG69899.1
OrganismRalstonia solanacearum (strain Po82) [Complete proteome] [HAMAP]
Taxonomic identifier1031711 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia ›

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively By similarity. PIRNR PIRNR038800

Catalytic activity

L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine. PIRNR PIRNR038800

L-kynurenine + H2O = anthranilate + L-alanine. PIRNR PIRNR038800

Cofactor

Pyridoxal phosphate By similarity. PIRNR PIRNR038800

Pathway

Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1. PIRNR PIRNR038800

Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3. PIRNR PIRNR038800

Subunit structure

Homodimer By similarity. PIRNR PIRNR038800

Sequence similarities

Belongs to the kynureninase family. PIRNR PIRNR038800

Sequences

Sequence LengthMass (Da)Tools
F6G4U4 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 20D59ACD45B2C434

FASTA41745,660
        10         20         30         40         50         60 
MTLTRNTCLE RDAADPIAPL RDAFALPDGV IYLDGNSLGA RPRAALARAQ QVVADEWGEG 

        70         80         90        100        110        120 
LIRSWNQSGW FDLPRRLGNK LAPLIGARPD EVVVTDTTSI NLFKVLAAAL RVQREDAPER 

       130        140        150        160        170        180 
KIIVSETHNF PTDLYIAEGL ADLLRDGYKL RLIDAPDELE AALGDDVAVT MLTHVNYKSG 

       190        200        210        220        230        240 
HMYDMAAVSA LAHRHGALAV WDLAHSAGAV PVDLHAGGAD YAIGCTYKYL NGGPGSPAFV 

       250        260        270        280        290        300 
WVSPALRERF WQPLSGWWGH ARPFAMESRY DAGAGIGRFL CGTQPITSMA MVECGLDLFA 

       310        320        330        340        350        360 
QTSMAALRAK SLALTDLFIE LIETRCAGYP LTLATPRDHA VRGSHVSYAH PDGFAVMQAL 

       370        380        390        400        410 
IARGVIGDYR EPHIMRFGFT PLYTRFVDVW DAVEVLRDVL ETGAWQSAQF NERTLVT

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References

[1]"Complete genome sequence of the plant pathogen Ralstonia solanacearum strain Po82."
Xu J., Zheng H.J., Liu L., Pan Z.C., Prior P., Tang B., Xu J.S., Zhang H., Tian Q., Zhang L.Q., Feng J.
J. Bacteriol. 193:4261-4262(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Po82 EMBL AEG69899.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002819 Genomic DNA. Translation: AEG69899.1.
RefSeqYP_006030435.1. NC_017574.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG69899; AEG69899; RSPO_c02606.
GeneID12626708.
KEGGrsn:RSPO_c02606.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01556.
OMAMLTHVNY.

Enzyme and pathway databases

UniPathwayUPA00253; UER00329.
UPA00334; UER00455.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR010111. Kynureninase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR14084. PTHR14084. 1 hit.
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
PIRSFPIRSF038800. KYNU. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01814. kynureninase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF6G4U4_RALS8
AccessionPrimary (citable) accession number: F6G4U4
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info