SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F6FWS0

- F6FWS0_ISOV2

UniProt

F6FWS0 - F6FWS0_ISOV2

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene
Isova_0706
Organism
Isoptericola variabilis (strain 225)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei48 – 481Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei148 – 1481Substrate By similarityUniRule annotation
Active sitei282 – 2821Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei339 – 3391Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciIVAR743718:GI39-718-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Isova_0706Imported
OrganismiIsoptericola variabilis (strain 225)
Taxonomic identifieri743718 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaePromicromonosporaceaeIsoptericola
ProteomesiUP000009236: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei48 – 481N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF6FWS0.

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6FWS0-1 [UniParc]FASTAAdd to Basket

« Hide

MRESLTVSSS DLAPGAPARA VVDLDAIRDN VRALRDHAPS SDLMAVVKAD    50
GYGHGMVPAA RAALAGGATW LGVATAHEAL ALRASGVTGD ARVLVWLLVP 100
GAPFADLVRA DVDVTVAAPW SVDEVAAGAR EAGRPARVHL KVDTGLSRNG 150
VTPADLPGVV RRLATLEASG EVRVVGVFSH LACADEPGHP SVARQAAAFD 200
DAARAVAAAG LRPEVRHLAN SAATLTAPEV HHDLVRPGIA VYGLSPVPQL 250
GPPGAYGLRP AMTLEARLGN VKAVPAGEGV SYGHLYTTPR DTVLGLVPLG 300
YADGIPRHAS GGSAGVGGPV AVGSGDARRV LRIAGRVCMD QVVLDLGPDA 350
TERPGDVATL FGASEGVAHG ATVPNAQDWA EAAGTISYEI VTRIGARVPR 400
TYAGKDVQP 409
Length:409
Mass (Da):41,655
Last modified:July 27, 2011 - v1
Checksum:iF0C19C775EAC85A9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002810 Genomic DNA. Translation: AEG43492.1.
RefSeqiWP_013837884.1. NC_015588.1.
YP_004541386.1. NC_015588.1.

Genome annotation databases

EnsemblBacteriaiAEG43492; AEG43492; Isova_0706.
GeneIDi10732306.
KEGGiiva:Isova_0706.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002810 Genomic DNA. Translation: AEG43492.1 .
RefSeqi WP_013837884.1. NC_015588.1.
YP_004541386.1. NC_015588.1.

3D structure databases

ProteinModelPortali F6FWS0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEG43492 ; AEG43492 ; Isova_0706 .
GeneIDi 10732306.
KEGGi iva:Isova_0706.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci IVAR743718:GI39-718-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 225.

Entry informationi

Entry nameiF6FWS0_ISOV2
AccessioniPrimary (citable) accession number: F6FWS0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 3, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi