F6FWS0 (F6FWS0_ISOV2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Ordered Locus Names:

Isova_0706

Organism

Isoptericola variabilis (strain 225) [Complete proteome] [HAMAP]

Taxonomic identifier

743718 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Promicromonosporaceae › Isoptericola › Isoptericola variabilis

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622 EMBL AEG43492.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F6FWS0 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: F0C19C775EAC85A9	FASTA	409	41,655
	10 20 30 40 50 60 MRESLTVSSS DLAPGAPARA VVDLDAIRDN VRALRDHAPS SDLMAVVKAD GYGHGMVPAA 70 80 90 100 110 120 RAALAGGATW LGVATAHEAL ALRASGVTGD ARVLVWLLVP GAPFADLVRA DVDVTVAAPW 130 140 150 160 170 180 SVDEVAAGAR EAGRPARVHL KVDTGLSRNG VTPADLPGVV RRLATLEASG EVRVVGVFSH 190 200 210 220 230 240 LACADEPGHP SVARQAAAFD DAARAVAAAG LRPEVRHLAN SAATLTAPEV HHDLVRPGIA 250 260 270 280 290 300 VYGLSPVPQL GPPGAYGLRP AMTLEARLGN VKAVPAGEGV SYGHLYTTPR DTVLGLVPLG 310 320 330 340 350 360 YADGIPRHAS GGSAGVGGPV AVGSGDARRV LRIAGRVCMD QVVLDLGPDA TERPGDVATL 370 380 390 400 FGASEGVAHG ATVPNAQDWA EAAGTISYEI VTRIGARVPR TYAGKDVQP

References

[1]

"Complete sequence of Isoptericola variabilis 225." US DOE Joint Genome Institute Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Zeytun A., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Siebers A., Allgaier M. , Thelen M., Hugenholtz P., Gladden J., Woyke T. Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 225.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002810 Genomic DNA. Translation: AEG43492.1.
RefSeq	YP_004541386.1. NC_015588.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEG43492; AEG43492; Isova_0706.
GeneID	10732306.
KEGG	iva:Isova_0706.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
BioCyc	IVAR743718:GI39-718-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F6FWS0_ISOV2

Accession

Primary (citable) accession number: F6FWS0

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)