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F6FWS0 (F6FWS0_ISOV2) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site481Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2821Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1481Substrate By similarity HAMAP-Rule MF_01201
Binding site3391Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue481N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F6FWS0 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: F0C19C775EAC85A9

FASTA40941,655
        10         20         30         40         50         60 
MRESLTVSSS DLAPGAPARA VVDLDAIRDN VRALRDHAPS SDLMAVVKAD GYGHGMVPAA 

        70         80         90        100        110        120 
RAALAGGATW LGVATAHEAL ALRASGVTGD ARVLVWLLVP GAPFADLVRA DVDVTVAAPW 

       130        140        150        160        170        180 
SVDEVAAGAR EAGRPARVHL KVDTGLSRNG VTPADLPGVV RRLATLEASG EVRVVGVFSH 

       190        200        210        220        230        240 
LACADEPGHP SVARQAAAFD DAARAVAAAG LRPEVRHLAN SAATLTAPEV HHDLVRPGIA 

       250        260        270        280        290        300 
VYGLSPVPQL GPPGAYGLRP AMTLEARLGN VKAVPAGEGV SYGHLYTTPR DTVLGLVPLG 

       310        320        330        340        350        360 
YADGIPRHAS GGSAGVGGPV AVGSGDARRV LRIAGRVCMD QVVLDLGPDA TERPGDVATL 

       370        380        390        400 
FGASEGVAHG ATVPNAQDWA EAAGTISYEI VTRIGARVPR TYAGKDVQP 

« Hide

References

[1]"Complete sequence of Isoptericola variabilis 225."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Zeytun A., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Siebers A., Allgaier M. expand/collapse author list , Thelen M., Hugenholtz P., Gladden J., Woyke T.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 225.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002810 Genomic DNA. Translation: AEG43492.1.
RefSeqYP_004541386.1. NC_015588.1.

3D structure databases

ProteinModelPortalF6FWS0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG43492; AEG43492; Isova_0706.
GeneID10732306.
KEGGiva:Isova_0706.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycIVAR743718:GI39-718-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF6FWS0_ISOV2
AccessionPrimary (citable) accession number: F6FWS0
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: February 19, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)