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Protein

Beta-galactosidase

Gene

Sinme_4624

Organism
Sinorhizobium meliloti (strain AK83)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei121 – 1211SubstrateUniRule annotation
Metal bindingi125 – 1251ZincUniRule annotation
Binding sitei159 – 1591SubstrateUniRule annotation
Active sitei160 – 1601Proton donorUniRule annotation
Binding sitei339 – 3391SubstrateUniRule annotation

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. galactose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciSMEL693982:GJDT-4690-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Short name:
Beta-galUniRule annotation
Gene namesi
Ordered Locus Names:Sinme_4624Imported
OrganismiSinorhizobium meliloti (strain AK83)Imported
Taxonomic identifieri693982 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000008705: Chromosome 2

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 42 family.UniRule annotation

Phylogenomic databases

KOiK12308.
OMAiMLGVCYY.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR013780. Glyco_hydro_13_b.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.

Sequencei

Sequence statusi: Complete.

F6E7W3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPLTSPNHFN SDARTPGRLE LGVCYYPEQW PRGKWAEDAR RMVELGLSWV
60 70 80 90 100
RIGEFAWAKI EPRSGEFHWE WLDEAIDVLG KAGLKVILGT PTAAPPKWLV
110 120 130 140 150
NRYPEILPVD ATGAVRKFGA RRHYCFSSRR YRSEAARITE AMARRYGEHI
160 170 180 190 200
YVHAWQTDNE YGDHDTIYSY SAEAVGAFRL WLAERYGSID ELNRAWGTSF
210 220 230 240 250
WSMRYDSFEE IDLPNNLVEE PSPTHGVDFI RFSSDQVKSF NKAQVDIIRA
260 270 280 290 300
HSPGRPVTHN FMSQNTDFDH YRVGEDIDIA SWDVYPMGGL LNGRLAAKDK
310 320 330 340 350
EHYLRVGDPD QPAFNHDLYR AVGRGRVWVM EQQPGPVNWA AHNQSPADGM
360 370 380 390 400
VRLWTWLAYA HGVDMVSYFR WRQAPFAQEQ FHAGLLLPNS EADQGYLEVA
410 420 430 440 450
EVVAEMKRLP EGEVRGKAQV AIVLDYESRW ATRVLPQGRS YSASAVALDW
460 470 480 490 500
YSTVARLGVD VDFIGQHSDI AGYKLILAPD LVIAEEAFVE RLTRADAKVV
510 520 530 540 550
FGARSGSKTR DMHIPEGLPP GPLAKLIDIS VSRVESLPEF HSETVLYGNE
560 570 580 590 600
AYEAGGWRET VRTSETVIAS FDGEYRNGAP ALVGNDKARY LAVAANGALL
610 620 630 640 650
DKVIGDALGW AGLESLPDLG DLRVTRRGNL RFAFNFGRIP AEVPAGASAE
660
FYVGGRTLKP VDVAIWRE
Length:668
Mass (Da):75,023
Last modified:July 27, 2011 - v1
Checksum:i99BC68EFE293992C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002782 Genomic DNA. Translation: AEG56291.1.
RefSeqiYP_004557171.1. NC_015596.1.

Genome annotation databases

EnsemblBacteriaiAEG56291; AEG56291; Sinme_4624.
GeneIDi10730665.
KEGGismk:Sinme_4624.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002782 Genomic DNA. Translation: AEG56291.1.
RefSeqiYP_004557171.1. NC_015596.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEG56291; AEG56291; Sinme_4624.
GeneIDi10730665.
KEGGismk:Sinme_4624.

Phylogenomic databases

KOiK12308.
OMAiMLGVCYY.

Enzyme and pathway databases

BioCyciSMEL693982:GJDT-4690-MONOMER.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR013780. Glyco_hydro_13_b.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AK83Imported.

Entry informationi

Entry nameiF6E7W3_SINMK
AccessioniPrimary (citable) accession number: F6E7W3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: February 4, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.