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F6DIC4 (F6DIC4_THETG) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase HAMAP-Rule MF_01006

EC=3.6.1.27 HAMAP-Rule MF_01006
Alternative name(s):
Bacitracin resistance protein HAMAP-Rule MF_01006
Undecaprenyl pyrophosphate phosphatase HAMAP-Rule MF_01006
Gene names
Name:uppP HAMAP-Rule MF_01006
Ordered Locus Names:Ththe16_0217 EMBL AEG32650.1
OrganismThermus thermophilus (strain SG0.5JP17-16) [Complete proteome] [HAMAP] EMBL AEG32650.1
Taxonomic identifier762633 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006 SAAS SAAS003824

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available By similarity. HAMAP-Rule MF_01006

Sequence similarities

Belongs to the UppP family. HAMAP-Rule MF_01006

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane9 – 3123Helical; By similarity HAMAP-Rule MF_01006
Transmembrane46 – 6621Helical; By similarity HAMAP-Rule MF_01006
Transmembrane80 – 10021Helical; By similarity HAMAP-Rule MF_01006
Transmembrane102 – 12221Helical; By similarity HAMAP-Rule MF_01006
Transmembrane137 – 15721Helical; By similarity HAMAP-Rule MF_01006
Transmembrane180 – 20021Helical; By similarity HAMAP-Rule MF_01006
Transmembrane209 – 22921Helical; By similarity HAMAP-Rule MF_01006
Transmembrane240 – 26021Helical; By similarity HAMAP-Rule MF_01006

Sequences

Sequence LengthMass (Da)Tools
F6DIC4 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 9DA10E925206A191

FASTA26128,291
        10         20         30         40         50         60 
MGRVSAWEAL LLGVVEGLTE FLPVSSTGHL TLLFHLLGLP VEEDPFLKTF LVAIQLGAIL 

        70         80         90        100        110        120 
AVLLLYGRRL AADRALWLRI AVAFVPTGVI GFLFYPLIKG VILGNDAVVA FFLFFVGAVL 

       130        140        150        160        170        180 
LFADRLAERA QHQDVKALPL ARVAWIGVFQ GLAALFPGTS RSGATILGGL LLGLNRQAAA 

       190        200        210        220        230        240 
EFSFLLALPT MFAAVGYDLW KSAPEVPEGG WSLLLLGFLA ALATALVTVR WMLAFVARHG 

       250        260 
FRPFALYRMA LAAVYAFFFL R 

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References

[1]"Complete sequence of chromosome of Thermus thermophilus SG0.5JP17-16."
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Allgaier M., Hugenholtz P. expand/collapse author list , Singer S., Gladden J., Woyke T., .
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SG0.5JP17-16.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002777 Genomic DNA. Translation: AEG32650.1.
RefSeqYP_005639777.1. NC_017272.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG32650; AEG32650; Ththe16_0217.
GeneID12261579.
KEGGtts:Ththe16_0217.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK06153.

Enzyme and pathway databases

BioCycTTHE762633:GLMG-229-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. Bacitracin-R_BacA.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF6DIC4_THETG
AccessionPrimary (citable) accession number: F6DIC4
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: May 29, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)