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F6DEQ7 (F6DEQ7_THETG) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
30S ribosomal protein S12 RuleBase RU003623 HAMAP-Rule MF_00403
Gene names
Name:rpsL HAMAP-Rule MF_00403
Ordered Locus Names:Ththe16_1715 EMBL AEG34110.1
OrganismThermus thermophilus (strain SG0.5JP17-16) [Complete proteome] [HAMAP] EMBL AEG34110.1
Taxonomic identifier762633 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length135 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit By similarity. HAMAP-Rule MF_00403

With S4 and S5 plays an important role in translational accuracy By similarity. HAMAP-Rule MF_00403

Subunit structure

Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex By similarity. HAMAP-Rule MF_00403

Sequence similarities

Belongs to the ribosomal protein S12P family. RuleBase RU003622 HAMAP-Rule MF_00403

Sequences

Sequence LengthMass (Da)Tools
F6DEQ7 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 287BC5D2E36913B7

FASTA13514,883
        10         20         30         40         50         60 
MVALPTINQL VRKGREKVRK KSKVPALKGA PFRRGVCTVV RTVTPKKPNS ALRKVAKVRL 

        70         80         90        100        110        120 
TSGYEVTAYI PGEGHNLQEH SVVLIRGGRV KDLPGVRYHI VRGVYDAAGV KDRKKSRSKY 

       130 
GTKKPKEAAK TAAKK 

« Hide

References

« Hide 'large scale' references
[1]"Complete sequence of chromosome of Thermus thermophilus SG0.5JP17-16."
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Allgaier M., Hugenholtz P. expand/collapse author list , Singer S., Gladden J., Woyke T.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SG0.5JP17-16.
[2]"A structural basis for streptomycin-induced misreading of the genetic code."
Demirci H., Murphy F., Murphy E., Gregory S.T., Dahlberg A.E., Jogl G.
Nat. Commun. 4:1355-1355(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.25 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002777 Genomic DNA. Translation: AEG34110.1.
RefSeqYP_005641237.1. NC_017272.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4DR1X-ray3.60L1-135[»]
4DR2X-ray3.25L1-135[»]
4DR3X-ray3.35L1-135[»]
4DR4X-ray3.97L1-135[»]
4DR5X-ray3.45L1-135[»]
4DR6X-ray3.30L1-135[»]
4DR7X-ray3.75L1-135[»]
ProteinModelPortalF6DEQ7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG34110; AEG34110; Ththe16_1715.
GeneID12261371.
KEGGtts:Ththe16_1715.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02950.
OMAPALQWGY.

Enzyme and pathway databases

BioCycTTHE762633:GLMG-1760-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00403_B. Ribosomal_S12_B.
InterProIPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view]
PANTHERPTHR11652. PTHR11652. 1 hit.
PfamPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSPR01034. RIBOSOMALS12.
SUPFAMSSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00981. rpsL_bact. 1 hit.
PROSITEPS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF6DEQ7_THETG
AccessionPrimary (citable) accession number: F6DEQ7
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: May 14, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)