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Protein

30S ribosomal protein S12

Gene

rpsL

Organism
Thermus thermophilus (strain SG0.5JP17-16)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.UniRule annotation
With S4 and S5 plays an important role in translational accuracy.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotationImported, RNA-binding, rRNA-bindingUniRule annotation, tRNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S12UniRule annotation
Gene namesi
Name:rpsLUniRule annotation
Ordered Locus Names:Ththe16_1715Imported
OrganismiThermus thermophilus (strain SG0.5JP17-16)Imported
Taxonomic identifieri762633 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000009233 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.UniRule annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4DR1X-ray3.60L1-135[»]
4DR2X-ray3.25L1-135[»]
4DR3X-ray3.35L1-135[»]
4DR4X-ray3.97L1-135[»]
4DR5X-ray3.45L1-135[»]
4DR6X-ray3.30L1-135[»]
4DR7X-ray3.75L1-135[»]
4LF4X-ray3.34L1-135[»]
4LF5X-ray3.75L1-135[»]
4LF6X-ray3.31L1-135[»]
4LF7X-ray3.15L1-135[»]
4LF8X-ray3.15L1-135[»]
4LF9X-ray3.28L1-135[»]
4LFAX-ray3.65L1-135[»]
4LFBX-ray3.01L1-135[»]
4LFCX-ray3.60L1-135[»]
4NXMX-ray3.65L1-135[»]
4NXNX-ray3.54L1-135[»]
ProteinModelPortaliF6DEQ7.
SMRiF6DEQ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uS12 family.UniRule annotation

Phylogenomic databases

KOiK02950.
OMAiKRGVCTA.
OrthoDBiPOG091H025P.

Family and domain databases

CDDicd03368. Ribosomal_S12. 1 hit.
HAMAPiMF_00403_B. Ribosomal_S12_B. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiView protein in Pfam
PF00164. Ribosom_S12_S23. 1 hit.
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSiPR01034. RIBOSOMALS12.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00981. rpsL_bact. 1 hit.
PROSITEiView protein in PROSITE
PS00055. RIBOSOMAL_S12. 1 hit.

Sequencei

Sequence statusi: Complete.

F6DEQ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVALPTINQL VRKGREKVRK KSKVPALKGA PFRRGVCTVV RTVTPKKPNS
60 70 80 90 100
ALRKVAKVRL TSGYEVTAYI PGEGHNLQEH SVVLIRGGRV KDLPGVRYHI
110 120 130
VRGVYDAAGV KDRKKSRSKY GTKKPKEAAK TAAKK
Length:135
Mass (Da):14,883
Last modified:July 27, 2011 - v1
Checksum:i287BC5D2E36913B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002777 Genomic DNA. Translation: AEG34110.1.
RefSeqiWP_008633430.1. NC_017272.1.

Genome annotation databases

EnsemblBacteriaiAEG34110; AEG34110; Ththe16_1715.
KEGGitts:Ththe16_1715.
PATRICifig|762633.3.peg.1704.

Similar proteinsi

Entry informationi

Entry nameiF6DEQ7_THETG
AccessioniPrimary (citable) accession number: F6DEQ7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 27, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported