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F6DBE5 (F6DBE5_THICA) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase HAMAP-Rule MF_01023

EC=2.6.1.9 HAMAP-Rule MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase HAMAP-Rule MF_01023
Gene names
Name:hisC HAMAP-Rule MF_01023
Ordered Locus Names:Thicy_0480 EMBL AEG31253.1
OrganismThioalkalimicrobium cyclicum (strain DSM 14477 / JCM 11371 / ALM1) [Complete proteome] [HAMAP]
Taxonomic identifier717773 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeThioalkalimicrobium

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP-Rule MF_01023 SAAS SAAS005861

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01023 SAAS SAAS005861

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP-Rule MF_01023 SAAS SAAS005861

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP-Rule MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2241N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01023

Sequences

Sequence LengthMass (Da)Tools
F6DBE5 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 6C606D7F56FDFB7C

FASTA36940,127
        10         20         30         40         50         60 
MAVAFNAVEQ AIDSLVRTEV RAINAYHVPP STNMIKLDAM ENPYGWPDDL RQAWLAKLAE 

        70         80         90        100        110        120 
LSLNRYPDPS ATELHQTLHR HLNLTSATGL LFGNGSDEII QLLIMAVNKP DAKVMSIAPT 

       130        140        150        160        170        180 
FVMYDMIARF LGADYCSVPL DESFQLDVDS FITAMIEQQP ALVFIAYPNN PTGNALSRQD 

       190        200        210        220        230        240 
VIRIIEAAPG LVVVDEAYHA FAEDSFVQDT CAYPNVLVMR TFSKVGLAGL RLGYLVGPVA 

       250        260        270        280        290        300 
WIEQIDKLRL PYNINTMTQA SALVALAHWP ILAEQALQIC QDRAELAKQL AELPGVAVYP 

       310        320        330        340        350        360 
SAANFIVIRL DLAGPTATDV FEGLKAVGIL IKNLSGQGGV LANCLRITVG SISENSQLLK 


GLAALLPSR 

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References

[1]"Complete sequence of Thioalkalimicrobium cyclicum ALM1."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Davenport K., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Kappler U., Woyke T.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 14477 / JCM 11371 / ALM1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002776 Genomic DNA. Translation: AEG31253.1.
RefSeqYP_004536732.1. NC_015581.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG31253; AEG31253; Thicy_0480.
GeneID10719280.
KEGGtcy:Thicy_0480.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00817.

Enzyme and pathway databases

UniPathwayUPA00031; UER00012.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01023. HisC_aminotrans_2.
InterProIPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. hisC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF6DBE5_THICA
AccessionPrimary (citable) accession number: F6DBE5
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)