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F6D953

- F6D953_THICA

UniProt

F6D953 - F6D953_THICA

Protein

Elongation factor Tu

Gene

tuf

Organism
Thioalkalimicrobium cyclicum (strain DSM 14477 / JCM 11371 / ALM1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:Thicy_0108Imported, Thicy_0120Imported
    OrganismiThioalkalimicrobium cyclicum (strain DSM 14477 / JCM 11371 / ALM1)Imported
    Taxonomic identifieri717773 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeThioalkalimicrobium
    ProteomesiUP000009232: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.
    OMAiGTEMCMP.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F6D953-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKAKFERTK PHVNVGTIGH VDHGKTTLTA ALTIVQGKKF GGDVKGYDQI    50
    DNAPEEKARG ITISTAHVEY ESESRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVCSAAD GPMPQTREHI LLSRQVGVPY IVVFLNKADM VDDEELLELV 150
    EMEVRELLSD YDFPGDDTPV IKGSALKAIE GDQSEIGEPA IGRLIEALDT 200
    YIPTPERDTD KPFLMPVEDV FSIQGRGTVV TGRIETGVVK VGETVEIVGI 250
    RDTVSTTVTG VEMFRKLLDQ GEAGDNVGVL LRGTKREDVE RGQVLSHVGK 300
    INPHTQFESE VYVLSKEEGG RHTPFFNGYR PQFYFRTTDV TGACELPSGV 350
    EMVMPGDNIQ MTITLINPIA MDEGLRFAIR EGGRTVGAGV VSKILK 396
    Length:396
    Mass (Da):43,183
    Last modified:July 27, 2011 - v1
    Checksum:i02662AF7317CDB14
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002776 Genomic DNA. Translation: AEG30884.1.
    CP002776 Genomic DNA. Translation: AEG30896.1.
    RefSeqiYP_004536363.1. NC_015581.1.
    YP_004536375.1. NC_015581.1.

    Genome annotation databases

    EnsemblBacteriaiAEG30884; AEG30884; Thicy_0108.
    AEG30896; AEG30896; Thicy_0120.
    GeneIDi10718901.
    10718914.
    KEGGitcy:Thicy_0108.
    tcy:Thicy_0120.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002776 Genomic DNA. Translation: AEG30884.1 .
    CP002776 Genomic DNA. Translation: AEG30896.1 .
    RefSeqi YP_004536363.1. NC_015581.1.
    YP_004536375.1. NC_015581.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEG30884 ; AEG30884 ; Thicy_0108 .
    AEG30896 ; AEG30896 ; Thicy_0120 .
    GeneIDi 10718901.
    10718914.
    KEGGi tcy:Thicy_0108.
    tcy:Thicy_0120.

    Phylogenomic databases

    KOi K02358.
    OMAi GTEMCMP.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Thioalkalimicrobium cyclicum ALM1."
      US DOE Joint Genome Institute
      Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Davenport K., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Kappler U., Woyke T.
      Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ALM1Imported and DSM 14477 / JCM 11371 / ALM1Imported.

    Entry informationi

    Entry nameiF6D953_THICA
    AccessioniPrimary (citable) accession number: F6D953
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3