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F6D1J3 (F6D1J3_METSW) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA ligase RuleBase RU000617 HAMAP-Rule MF_00407

EC=6.5.1.1 RuleBase RU000617 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:MSWAN_0175 EMBL AEG17221.1
OrganismMethanobacterium sp. (strain SWAN-1) [Complete proteome] [HAMAP] EMBL AEG17221.1
Taxonomic identifier868131 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanobacterium

Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407 RuleBase RU004196

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2581N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2561ATP By similarity HAMAP-Rule MF_00407
Binding site2631ATP By similarity HAMAP-Rule MF_00407
Binding site2781ATP By similarity HAMAP-Rule MF_00407
Binding site3081ATP By similarity HAMAP-Rule MF_00407
Binding site3471ATP By similarity HAMAP-Rule MF_00407
Binding site4241ATP By similarity HAMAP-Rule MF_00407
Binding site4301ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
F6D1J3 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 4D906B059857AFA0

FASTA56163,264
        10         20         30         40         50         60 
MNSKINMKYM ELVEVYEALD STTKRLEKTS ILAKFFKIMG NEEPELLPIV TLMSLGRIFP 

        70         80         90        100        110        120 
TWSEEELGLG SKLLMKAISL VAGVGPDDVE NMTRDAGDIG LAAETLLKRK QQSTLFARQP 

       130        140        150        160        170        180 
LTIEKVHSNL IKITKISGNR AQNKKMEILR ELFSSASPKE AKYITRTVLE ELRVGVGEGT 

       190        200        210        220        230        240 
IKDAISEAFE VEKTAVERAH MLTNDLGLVA EVAKEEGEEG LGKLTLKPGK PVKPMLAQLS 

       250        260        270        280        290        300 
PGIKISVEEM GWALCETKYD GIRVQIHRLG DDINIFTRRL ENISNAVPEI VEYIRKSLPA 

       310        320        330        340        350        360 
CDFIVEGEII VTRDGKPISF QYILQRVRRK YDIEKMREKV PLKLYLFDVL YYDGPQIDTP 

       370        380        390        400        410        420 
FEERRRILES IVTVTEHKLE LSSQVKTTPE EIWKAEDLFT ASIKGGHEGI MIKDPHAPYM 

       430        440        450        460        470        480 
PGIRGKKMLK LKAVPETLDL VIVGGTYGKG RRAHVIGSYL LAVRDENNDF KTLAHAATGL 

       490        500        510        520        530        540 
DDNMLIELSR MVEPLIVKKM GRKVEITPSI ILEIAYSEIV KSPEYESGYS LRFPVVKRIR 

       550        560 
EDIGLDDIDT VERVDSMFKE V 

« Hide

References

[1]"Complete sequence of Methanobacterium sp. SWAN-1."
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Chertkov O., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Cadillo-Quiroz H., Imachi H. expand/collapse author list , Zinder S., Liu W., Woyke T.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SWAN-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002772 Genomic DNA. Translation: AEG17221.1.
RefSeqYP_004519022.1. NC_015574.1.

3D structure databases

ProteinModelPortalF6D1J3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG17221; AEG17221; MSWAN_0175.
GeneID10667653.
KEGGmew:MSWAN_0175.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK10747.
OMAARVQVHK.

Enzyme and pathway databases

BioCycMSP868131:GHW8-177-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF6D1J3_METSW
AccessionPrimary (citable) accession number: F6D1J3
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 11, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)