Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F6D1J3

- F6D1J3_METPW

UniProt

F6D1J3 - F6D1J3_METPW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

DNA ligase

Gene

lig

Organism
Methanobacterium paludis (strain DSM 25820 / JCM 18151 / SWAN1)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

Note: Divalent metal cations.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei256 – 2561ATPUniRule annotation
Active sitei258 – 2581N6-AMP-lysine intermediateUniRule annotation
Binding sitei263 – 2631ATPUniRule annotation
Binding sitei278 – 2781ATPUniRule annotation
Binding sitei308 – 3081ATPUniRule annotation
Binding sitei347 – 3471ATPUniRule annotation
Binding sitei424 – 4241ATPUniRule annotation
Binding sitei430 – 4301ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
  4. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. DNA biosynthetic process Source: InterPro
  4. DNA ligation involved in DNA repair Source: InterPro
  5. DNA recombination Source: UniProtKB-HAMAP
  6. DNA replication Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMSP868131:GHW8-177-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]UniRule annotation
Gene namesi
Name:ligUniRule annotation
Ordered Locus Names:MSWAN_0175Imported
OrganismiMethanobacterium paludis (strain DSM 25820 / JCM 18151 / SWAN1)Imported
Taxonomic identifieri868131 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanobacterium
ProteomesiUP000009231: Chromosome

Structurei

3D structure databases

ProteinModelPortaliF6D1J3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OMAiARVQVHK.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPiMF_00407. DNA_ligase.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6D1J3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSKINMKYM ELVEVYEALD STTKRLEKTS ILAKFFKIMG NEEPELLPIV
60 70 80 90 100
TLMSLGRIFP TWSEEELGLG SKLLMKAISL VAGVGPDDVE NMTRDAGDIG
110 120 130 140 150
LAAETLLKRK QQSTLFARQP LTIEKVHSNL IKITKISGNR AQNKKMEILR
160 170 180 190 200
ELFSSASPKE AKYITRTVLE ELRVGVGEGT IKDAISEAFE VEKTAVERAH
210 220 230 240 250
MLTNDLGLVA EVAKEEGEEG LGKLTLKPGK PVKPMLAQLS PGIKISVEEM
260 270 280 290 300
GWALCETKYD GIRVQIHRLG DDINIFTRRL ENISNAVPEI VEYIRKSLPA
310 320 330 340 350
CDFIVEGEII VTRDGKPISF QYILQRVRRK YDIEKMREKV PLKLYLFDVL
360 370 380 390 400
YYDGPQIDTP FEERRRILES IVTVTEHKLE LSSQVKTTPE EIWKAEDLFT
410 420 430 440 450
ASIKGGHEGI MIKDPHAPYM PGIRGKKMLK LKAVPETLDL VIVGGTYGKG
460 470 480 490 500
RRAHVIGSYL LAVRDENNDF KTLAHAATGL DDNMLIELSR MVEPLIVKKM
510 520 530 540 550
GRKVEITPSI ILEIAYSEIV KSPEYESGYS LRFPVVKRIR EDIGLDDIDT
560
VERVDSMFKE V
Length:561
Mass (Da):63,264
Last modified:July 27, 2011 - v1
Checksum:i4D906B059857AFA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002772 Genomic DNA. Translation: AEG17221.1.
RefSeqiWP_013824723.1. NC_015574.1.
YP_004519022.1. NC_015574.1.

Genome annotation databases

EnsemblBacteriaiAEG17221; AEG17221; MSWAN_0175.
GeneIDi10667653.
KEGGimew:MSWAN_0175.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002772 Genomic DNA. Translation: AEG17221.1 .
RefSeqi WP_013824723.1. NC_015574.1.
YP_004519022.1. NC_015574.1.

3D structure databases

ProteinModelPortali F6D1J3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEG17221 ; AEG17221 ; MSWAN_0175 .
GeneIDi 10667653.
KEGGi mew:MSWAN_0175.

Phylogenomic databases

KOi K10747.
OMAi ARVQVHK.

Enzyme and pathway databases

BioCyci MSP868131:GHW8-177-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPi MF_00407. DNA_ligase.
InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Methanobacterium sp. SWAN-1."
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Chertkov O., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Cadillo-Quiroz H., Imachi H.
    , Zinder S., Liu W., Woyke T.
    Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 25820 / JCM 18151 / SWAN1Imported.

Entry informationi

Entry nameiF6D1J3_METPW
AccessioniPrimary (citable) accession number: F6D1J3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 26, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3