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Protein

Malonyl CoA-acyl carrier protein transacylase

Gene

Desku_2295

Organism
Desulfotomaculum kuznetsovii (strain DSM 6115 / VKM B-1805 / 17)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei90 – 901UniRule annotation
Active sitei199 – 1991UniRule annotation

GO - Molecular functioni

  1. [acyl-carrier-protein] S-malonyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

BioCyciDKUZ760568:GHV4-2336-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Malonyl CoA-acyl carrier protein transacylaseUniRule annotation (EC:2.3.1.39UniRule annotation)
Gene namesi
Ordered Locus Names:Desku_2295Imported
OrganismiDesulfotomaculum kuznetsovii (strain DSM 6115 / VKM B-1805 / 17)Imported
Taxonomic identifieri760568 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfotomaculum
ProteomesiUP000009229: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the fabD family.UniRule annotation

Phylogenomic databases

KOiK00645.
OMAiPVVTNVE.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
IPR020801. PKS_acyl_transferase.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SMARTiSM00827. PKS_AT. 1 hit.
[Graphical view]
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.

Sequencei

Sequence statusi: Complete.

F6CNM2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKLAFIFPGQ GSQYVGMGRQ MYECFPAARR TFEEADSSLG FTLSRLCFEG
60 70 80 90 100
PAEELQHTVN AQPAILTVSV ACLRVLQEKG VVPDVAAGHS LGEYSALVAA
110 120 130 140 150
GAMTFADAVK IVRKRGQFMQ EAVPLGAGGM MAVLGLDVPT AQEICRRASD
160 170 180 190 200
AGVVEAVNLN CPGQVVIAGE TQALERACVL AKEAGARRCV PLAVSAPFHS
210 220 230 240 250
SLMRPAGEKL ARELEQVVVA DPRFPVVANV TADYVTSKEE VKRLLVQQVY
260 270 280 290 300
SPVRWEESMR RLIDGGIRAF IEVGPGTVLC GLLRKINRQV NCWSVQDPES
310
LEKVLACLKE VS
Length:312
Mass (Da):33,632
Last modified:July 27, 2011 - v1
Checksum:i48CF257E954B4AB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002770 Genomic DNA. Translation: AEG15831.1.
RefSeqiYP_004517632.1. NC_015573.1.

Genome annotation databases

EnsemblBacteriaiAEG15831; AEG15831; Desku_2295.
GeneIDi10666185.
KEGGidku:Desku_2295.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002770 Genomic DNA. Translation: AEG15831.1.
RefSeqiYP_004517632.1. NC_015573.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEG15831; AEG15831; Desku_2295.
GeneIDi10666185.
KEGGidku:Desku_2295.

Phylogenomic databases

KOiK00645.
OMAiPVVTNVE.

Enzyme and pathway databases

BioCyciDKUZ760568:GHV4-2336-MONOMER.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
IPR020801. PKS_acyl_transferase.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SMARTiSM00827. PKS_AT. 1 hit.
[Graphical view]
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Desulfotomaculum kuznetsovii DSM 6115."
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Lu M., Saunders E., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Nazina T.
    , Ivanova A., Parshina S., Kuever J., Muyzer G., Plugge C., Stams A., Woyke T.
    Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 6115 / VKM B-1805 / 17Imported.

Entry informationi

Entry nameiF6CNM2_DESK7
AccessioniPrimary (citable) accession number: F6CNM2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: February 4, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.