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F6CDS8

- F6CDS8_LACKZ

UniProt

F6CDS8 - F6CDS8_LACKZ

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Protein

Branched-chain-amino-acid aminotransferase

Gene

WANG_0372

Organism
Lactobacillus kefiranofaciens (strain ZW3)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate.UniRule annotation
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.UniRule annotation
L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate.UniRule annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. L-isoleucine transaminase activity Source: UniProtKB-EC
  2. L-leucine transaminase activity Source: UniProtKB-EC
  3. L-valine transaminase activity Source: UniProtKB-EC

GO - Biological processi

  1. isoleucine biosynthetic process Source: UniProtKB-UniPathway
  2. leucine biosynthetic process Source: UniProtKB-UniPathway
  3. valine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Branched-chain amino acid biosynthesisUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciLKEF1033837:GHZJ-405-MONOMER.
UniPathwayiUPA00047; UER00058.
UPA00048; UER00073.
UPA00049; UER00062.

Names & Taxonomyi

Protein namesi
Recommended name:
Branched-chain-amino-acid aminotransferaseUniRule annotation (EC:2.6.1.42UniRule annotation)
Gene namesi
Ordered Locus Names:WANG_0372Imported
OrganismiLactobacillus kefiranofaciens (strain ZW3)Imported
Taxonomic identifieri1033837 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000009228: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei186 – 1861N6-(pyridoxal phosphate)lysineUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

KOiK00826.

Family and domain databases

InterProiIPR001544. Aminotrans_IV.
IPR018300. Aminotrans_IV_CS.
IPR005786. B_amino_transII.
[Graphical view]
PANTHERiPTHR11825. PTHR11825. 1 hit.
PfamiPF01063. Aminotran_4. 1 hit.
[Graphical view]
PIRSFiPIRSF006468. BCAT1. 1 hit.
SUPFAMiSSF56752. SSF56752. 1 hit.
TIGRFAMsiTIGR01123. ilvE_II. 1 hit.
PROSITEiPS00770. AA_TRANSFER_CLASS_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6CDS8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKTRPEDLN WNKLGFKYHD LPYRWVDEFK DGKWQGGHLT QDSSITFNEA
60 70 80 90 100
AEELHYGQEI FEGLKAYRRK DGGINLFRPD QNAKRMANSA KRLLMEPYPE
110 120 130 140 150
DKFIKAVKEV VKANQDFVPP YGSDGTLYLR PFMMGMQSVV GVSPSETYQF
160 170 180 190 200
RIYATPVGAY VKGLKPMPYE VSDYDRAAPA GTGQAKTAGN YASSLMPSLI
210 220 230 240 250
AKKNGFADAL YLDPKEHKYI DEFGGANFFG ITKEGQFQTP KSDSILPSIT
260 270 280 290 300
KRSILKLAKD LDLDPIETKI PINEIDRFAE TGAMGTAAVI SPVGSLTYKG
310 320 330 340
KKHVFGSETK AGPITQKLYD TLFGIQVGDL ADNYNWVVKL N
Length:341
Mass (Da):38,100
Last modified:July 27, 2011 - v1
Checksum:iC0EF5E3F6DFA955C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002764 Genomic DNA. Translation: AEG40067.1.
RefSeqiYP_004562169.1. NC_015602.1.

Genome annotation databases

EnsemblBacteriaiAEG40067; AEG40067; WANG_0372.
GeneIDi10749855.
KEGGilke:WANG_0372.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002764 Genomic DNA. Translation: AEG40067.1 .
RefSeqi YP_004562169.1. NC_015602.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEG40067 ; AEG40067 ; WANG_0372 .
GeneIDi 10749855.
KEGGi lke:WANG_0372.

Phylogenomic databases

KOi K00826.

Enzyme and pathway databases

UniPathwayi UPA00047 ; UER00058 .
UPA00048 ; UER00073 .
UPA00049 ; UER00062 .
BioCyci LKEF1033837:GHZJ-405-MONOMER.

Family and domain databases

InterProi IPR001544. Aminotrans_IV.
IPR018300. Aminotrans_IV_CS.
IPR005786. B_amino_transII.
[Graphical view ]
PANTHERi PTHR11825. PTHR11825. 1 hit.
Pfami PF01063. Aminotran_4. 1 hit.
[Graphical view ]
PIRSFi PIRSF006468. BCAT1. 1 hit.
SUPFAMi SSF56752. SSF56752. 1 hit.
TIGRFAMsi TIGR01123. ilvE_II. 1 hit.
PROSITEi PS00770. AA_TRANSFER_CLASS_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Lactobacillus kefiranofaciens ZW3."
    Wang Y., Wang J., Ahmed Z., Bai X., Wang J.
    J. Bacteriol. 193:4280-4281(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ZW3Imported.

Entry informationi

Entry nameiF6CDS8_LACKZ
AccessioniPrimary (citable) accession number: F6CDS8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 26, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3