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F6CDS8

- F6CDS8_LACKZ

UniProt

F6CDS8 - F6CDS8_LACKZ

Protein

Branched-chain-amino-acid aminotransferase

Gene

WANG_0372

Organism
Lactobacillus kefiranofaciens (strain ZW3)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate.UniRule annotation
    L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.UniRule annotation
    L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. L-isoleucine transaminase activity Source: UniProtKB-EC
    2. L-leucine transaminase activity Source: UniProtKB-EC
    3. L-valine transaminase activity Source: UniProtKB-EC

    GO - Biological processi

    1. isoleucine biosynthetic process Source: UniProtKB-UniPathway
    2. leucine biosynthetic process Source: UniProtKB-UniPathway
    3. valine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    AminotransferaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Branched-chain amino acid biosynthesisUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciLKEF1033837:GHZJ-405-MONOMER.
    UniPathwayiUPA00047; UER00058.
    UPA00048; UER00073.
    UPA00049; UER00062.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Branched-chain-amino-acid aminotransferaseUniRule annotation (EC:2.6.1.42UniRule annotation)
    Gene namesi
    Ordered Locus Names:WANG_0372Imported
    OrganismiLactobacillus kefiranofaciens (strain ZW3)Imported
    Taxonomic identifieri1033837 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000009228: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei186 – 1861N6-(pyridoxal phosphate)lysineUniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

    Phylogenomic databases

    KOiK00826.

    Family and domain databases

    InterProiIPR001544. Aminotrans_IV.
    IPR018300. Aminotrans_IV_CS.
    IPR005786. B_amino_transII.
    [Graphical view]
    PANTHERiPTHR11825. PTHR11825. 1 hit.
    PfamiPF01063. Aminotran_4. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006468. BCAT1. 1 hit.
    SUPFAMiSSF56752. SSF56752. 1 hit.
    TIGRFAMsiTIGR01123. ilvE_II. 1 hit.
    PROSITEiPS00770. AA_TRANSFER_CLASS_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F6CDS8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVKTRPEDLN WNKLGFKYHD LPYRWVDEFK DGKWQGGHLT QDSSITFNEA    50
    AEELHYGQEI FEGLKAYRRK DGGINLFRPD QNAKRMANSA KRLLMEPYPE 100
    DKFIKAVKEV VKANQDFVPP YGSDGTLYLR PFMMGMQSVV GVSPSETYQF 150
    RIYATPVGAY VKGLKPMPYE VSDYDRAAPA GTGQAKTAGN YASSLMPSLI 200
    AKKNGFADAL YLDPKEHKYI DEFGGANFFG ITKEGQFQTP KSDSILPSIT 250
    KRSILKLAKD LDLDPIETKI PINEIDRFAE TGAMGTAAVI SPVGSLTYKG 300
    KKHVFGSETK AGPITQKLYD TLFGIQVGDL ADNYNWVVKL N 341
    Length:341
    Mass (Da):38,100
    Last modified:July 27, 2011 - v1
    Checksum:iC0EF5E3F6DFA955C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002764 Genomic DNA. Translation: AEG40067.1.
    RefSeqiYP_004562169.1. NC_015602.1.

    Genome annotation databases

    EnsemblBacteriaiAEG40067; AEG40067; WANG_0372.
    GeneIDi10749855.
    KEGGilke:WANG_0372.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002764 Genomic DNA. Translation: AEG40067.1 .
    RefSeqi YP_004562169.1. NC_015602.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEG40067 ; AEG40067 ; WANG_0372 .
    GeneIDi 10749855.
    KEGGi lke:WANG_0372.

    Phylogenomic databases

    KOi K00826.

    Enzyme and pathway databases

    UniPathwayi UPA00047 ; UER00058 .
    UPA00048 ; UER00073 .
    UPA00049 ; UER00062 .
    BioCyci LKEF1033837:GHZJ-405-MONOMER.

    Family and domain databases

    InterProi IPR001544. Aminotrans_IV.
    IPR018300. Aminotrans_IV_CS.
    IPR005786. B_amino_transII.
    [Graphical view ]
    PANTHERi PTHR11825. PTHR11825. 1 hit.
    Pfami PF01063. Aminotran_4. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006468. BCAT1. 1 hit.
    SUPFAMi SSF56752. SSF56752. 1 hit.
    TIGRFAMsi TIGR01123. ilvE_II. 1 hit.
    PROSITEi PS00770. AA_TRANSFER_CLASS_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Lactobacillus kefiranofaciens ZW3."
      Wang Y., Wang J., Ahmed Z., Bai X., Wang J.
      J. Bacteriol. 193:4280-4281(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ZW3Imported.

    Entry informationi

    Entry nameiF6CDS8_LACKZ
    AccessioniPrimary (citable) accession number: F6CDS8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3