Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Branched-chain-amino-acid aminotransferase

Gene

WANG_0372

Organism
Lactobacillus kefiranofaciens (strain ZW3)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate.UniRule annotation
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.UniRule annotation
L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Pathwayi

GO - Molecular functioni

  1. L-isoleucine transaminase activity Source: UniProtKB-EC
  2. L-leucine transaminase activity Source: UniProtKB-EC
  3. L-valine transaminase activity Source: UniProtKB-EC

GO - Biological processi

  1. isoleucine biosynthetic process Source: UniProtKB-UniPathway
  2. leucine biosynthetic process Source: UniProtKB-UniPathway
  3. valine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Branched-chain amino acid biosynthesisUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciLKEF1033837:GHZJ-405-MONOMER.
UniPathwayiUPA00047; UER00058.
UPA00048; UER00073.
UPA00049; UER00062.

Names & Taxonomyi

Protein namesi
Recommended name:
Branched-chain-amino-acid aminotransferaseUniRule annotation (EC:2.6.1.42UniRule annotation)
Gene namesi
Ordered Locus Names:WANG_0372Imported
OrganismiLactobacillus kefiranofaciens (strain ZW3)Imported
Taxonomic identifieri1033837 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000009228: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

KOiK00826.

Family and domain databases

InterProiIPR001544. Aminotrans_IV.
IPR018300. Aminotrans_IV_CS.
IPR005786. B_amino_transII.
[Graphical view]
PANTHERiPTHR11825. PTHR11825. 1 hit.
PfamiPF01063. Aminotran_4. 1 hit.
[Graphical view]
PIRSFiPIRSF006468. BCAT1. 1 hit.
SUPFAMiSSF56752. SSF56752. 1 hit.
TIGRFAMsiTIGR01123. ilvE_II. 1 hit.
PROSITEiPS00770. AA_TRANSFER_CLASS_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6CDS8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKTRPEDLN WNKLGFKYHD LPYRWVDEFK DGKWQGGHLT QDSSITFNEA
60 70 80 90 100
AEELHYGQEI FEGLKAYRRK DGGINLFRPD QNAKRMANSA KRLLMEPYPE
110 120 130 140 150
DKFIKAVKEV VKANQDFVPP YGSDGTLYLR PFMMGMQSVV GVSPSETYQF
160 170 180 190 200
RIYATPVGAY VKGLKPMPYE VSDYDRAAPA GTGQAKTAGN YASSLMPSLI
210 220 230 240 250
AKKNGFADAL YLDPKEHKYI DEFGGANFFG ITKEGQFQTP KSDSILPSIT
260 270 280 290 300
KRSILKLAKD LDLDPIETKI PINEIDRFAE TGAMGTAAVI SPVGSLTYKG
310 320 330 340
KKHVFGSETK AGPITQKLYD TLFGIQVGDL ADNYNWVVKL N
Length:341
Mass (Da):38,100
Last modified:July 27, 2011 - v1
Checksum:iC0EF5E3F6DFA955C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002764 Genomic DNA. Translation: AEG40067.1.
RefSeqiYP_004562169.1. NC_015602.1.

Genome annotation databases

EnsemblBacteriaiAEG40067; AEG40067; WANG_0372.
GeneIDi10749855.
KEGGilke:WANG_0372.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002764 Genomic DNA. Translation: AEG40067.1.
RefSeqiYP_004562169.1. NC_015602.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEG40067; AEG40067; WANG_0372.
GeneIDi10749855.
KEGGilke:WANG_0372.

Phylogenomic databases

KOiK00826.

Enzyme and pathway databases

UniPathwayiUPA00047; UER00058.
UPA00048; UER00073.
UPA00049; UER00062.
BioCyciLKEF1033837:GHZJ-405-MONOMER.

Family and domain databases

InterProiIPR001544. Aminotrans_IV.
IPR018300. Aminotrans_IV_CS.
IPR005786. B_amino_transII.
[Graphical view]
PANTHERiPTHR11825. PTHR11825. 1 hit.
PfamiPF01063. Aminotran_4. 1 hit.
[Graphical view]
PIRSFiPIRSF006468. BCAT1. 1 hit.
SUPFAMiSSF56752. SSF56752. 1 hit.
TIGRFAMsiTIGR01123. ilvE_II. 1 hit.
PROSITEiPS00770. AA_TRANSFER_CLASS_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Lactobacillus kefiranofaciens ZW3."
    Wang Y., Wang J., Ahmed Z., Bai X., Wang J.
    J. Bacteriol. 193:4280-4281(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ZW3Imported.

Entry informationi

Entry nameiF6CDS8_LACKZ
AccessioniPrimary (citable) accession number: F6CDS8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: February 4, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.