Skip Header

Contribute Send feedback
Read comments (?) or add your own

F6CDM1 (F6CDM1_LACKZ) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylmuramate--L-alanine ligase HAMAP-Rule MF_00046
EC=6.3.2.8 HAMAP-Rule MF_00046
Alternative name(s):
UDP-N-acetylmuramoyl-L-alanine synthetase HAMAP-Rule MF_00046
Gene names
Name:murC HAMAP-Rule MF_00046 EMBL AEG39930.1
Ordered Locus Names:WANG_0235 EMBL AEG39930.1
OrganismLactobacillus kefiranofaciens (strain ZW3) [Complete proteome] [HAMAP]
Taxonomic identifier1033837 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus ›

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00046 SAAS SAAS005758

Catalytic activity

ATP + UDP-N-acetylmuramate + L-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine. HAMAP-Rule MF_00046 SAAS SAAS005758

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00046 SAAS SAAS005758

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00046 SAAS SAAS005758.

Sequence similarities

Belongs to the MurCDEF family. HAMAP-Rule MF_00046 RuleBase RU003630

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding114 – 1207ATP By similarity HAMAP-Rule MF_00046

Sequences

Sequence LengthMass (Da)Tools
F6CDM1 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 06EF48014421692E

FASTA43748,895
        10         20         30         40         50         60 
MLDKNKQIWF IGIKGTGMAS LALLLHDLGY NVAGSDIEKY TFTQVPLEKA GIEVKNFDPN 

        70         80         90        100        110        120 
NIKSNDEQVI VKGNAFKEDN PEVKACLDKD VKWQSYPDTV EEVVQSHTSI GVSGTHGKTS 

       130        140        150        160        170        180 
TTSLLSHVLG EVAPTSYLIG DGRGKGVAGS RFFVYEADEY RRHFLAYHPD YQIMTNIDFD 

       190        200        210        220        230        240 
HPDYFKDQAD YTSAFQSAAD QTKKALFVWG DDKRLQSLKT DIPKYTYGFS DSDDFQATDI 

       250        260        270        280        290        300 
KKSTTGSKFH VLAHGKDLGE FEIHLFGDHS ILNSTAVIAV AYTEKVPMED IKKGLPSFMG 

       310        320        330        340        350        360 
AKRRFSEKDF GDIAVIDDYA HHPTEMRATI QAARQKFPDK KLVVVFQPHT FSRTKKYQKD 

       370        380        390        400        410        420 
FEEILSDVDK AYVTPIYASA REANGDISSE DLVKNIPGSE VIDLDNIADL TKNKNSVIVF 

       430 
MGAGDIPKYE DAFEKLL

« Hide

References

[1]"Complete genome sequence of Lactobacillus kefiranofaciens ZW3."
Wang Y., Wang J., Ahmed Z., Bai X., Wang J.
J. Bacteriol. 193:4280-4281(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ZW3 EMBL AEG39930.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002764 Genomic DNA. Translation: AEG39930.1.
RefSeqYP_004562032.1. NC_015602.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG39930; AEG39930; WANG_0235.
GeneID10749718.
KEGGlke:WANG_0235.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01924.

Enzyme and pathway databases

BioCycLKEF1033837:GHZJ-290-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.40.1190.10. 1 hit.
3.40.50.720. 1 hit.
3.90.190.20. 1 hit.
HAMAPMF_00046. MurC.
InterProIPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR016040. NAD(P)-bd_dom.
IPR005758. UDP-N-AcMur_Ala_ligase.
[Graphical view]
PANTHERPTHR23135:SF5. PTHR23135:SF5. 1 hit.
PfamPF01225. Mur_ligase. 1 hit.
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMSSF53244. Mur_ligase_C. 1 hit.
SSF53623. Mur_ligase_cen. 1 hit.
TIGRFAMsTIGR01082. murC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF6CDM1_LACKZ
AccessionPrimary (citable) accession number: F6CDM1
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info