Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

F6BM26

- F6BM26_SINMB

UniProt

F6BM26 - F6BM26_SINMB

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

SinmeB_1077

Organism
Sinorhizobium meliloti (strain BL225C)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.

    Cofactori

    Binds 1 lipoyl cofactor covalently.UniRule annotation
    Binds 2 lipoyl cofactors covalently.UniRule annotation
    Binds 3 lipoyl cofactors covalently.UniRule annotation

    GO - Molecular functioni

    1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pyruvate metabolic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotationImported, Transferase

    Keywords - Ligandi

    PyruvateImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
    Gene namesi
    Ordered Locus Names:SinmeB_1077Imported
    OrganismiSinorhizobium meliloti (strain BL225C)Imported
    Taxonomic identifieri698936 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
    ProteomesiUP000008709: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. pyruvate dehydrogenase complex Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliF6BM26.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 lipoyl-binding domain.UniRule annotation

    Keywords - Domaini

    LipoylUniRule annotationSAAS annotation

    Phylogenomic databases

    KOiK00627.

    Family and domain databases

    Gene3Di3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view]
    PfamiPF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F6BM26-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPINITMPAL SPTMEEGNLA KWLVKEGDKV KSGDVIAEIE TDKATMEVEA    50
    VDEGTVAKIV VPAGTEGVKV NALIAVLAAE GEDVATAAKG GNGAAGAVPA 100
    PKPKETAETA PAAAPAPAAA PAPQAAAPAS PAPADGEGKR IFSSPLARRL 150
    AKEAGIDLSA IAGSGPHGRV VKKDVETAVS GGAAKPAGAP AAAPAPATLA 200
    KGMSEDAVLK LFEPGSYELV PHDGMRKTIA KRLVESKQTI PHFYVSVDCE 250
    LDALMALRAQ LNAAAPEKDG KPVYKLSVND MVIKALALAL RDVPDANVSW 300
    TDQNMVKHKH ADVGVAVSIP GGLITPIVRQ AELKSLSAIS NEMKDLGKRA 350
    KERKLKPEEY QGGTTAVSNM GMMGVKDFAA VVNPPHATIL AVGAGEDRVV 400
    VRNKEMVIAN VMTVTLSTDH RCVDGALGAE LLAAFKRYIE NPMGMLV 447
    Length:447
    Mass (Da):46,140
    Last modified:July 27, 2011 - v1
    Checksum:i48B1CAC4E2FDC2AC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002740 Genomic DNA. Translation: AEG04005.1.
    RefSeqiYP_005713248.1. NC_017322.1.

    Genome annotation databases

    EnsemblBacteriaiAEG04005; AEG04005; SinmeB_1077.
    GeneIDi12302569.
    KEGGismq:SinmeB_1077.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002740 Genomic DNA. Translation: AEG04005.1 .
    RefSeqi YP_005713248.1. NC_017322.1.

    3D structure databases

    ProteinModelPortali F6BM26.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEG04005 ; AEG04005 ; SinmeB_1077 .
    GeneIDi 12302569.
    KEGGi smq:SinmeB_1077.

    Phylogenomic databases

    KOi K00627.

    Family and domain databases

    Gene3Di 3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view ]
    Pfami PF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BL225CImported.

    Entry informationi

    Entry nameiF6BM26_SINMB
    AccessioniPrimary (citable) accession number: F6BM26
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3