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Protein

Xylose isomerase

Gene

xylA

Organism
Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciTXYL858215:G1GRK-2197-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Thexy_2149Imported
OrganismiThermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)Imported
Taxonomic identifieri858215 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisThermoanaerobacterium
Proteomesi
  • UP000007239 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi858215.Thexy_2149

Structurei

3D structure databases

ProteinModelPortaliF6BKS4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini154 – 285AP_endonuc_2InterPro annotationAdd BLAST132

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

F6BKS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKYFENVSK IKYEGPKSNN PYSFKFYNPE EVIDGKTMEE HLRFSIAYWH
60 70 80 90 100
TFTADGTDQF GKATMQRPWN HYTDPMDIAK ARVEAAFEFF DKINAPYFCF
110 120 130 140 150
HDRDIAPEGD TLRETNKNLD TIVAMIKDYL KTSKTKVLWG TANLFSNPRF
160 170 180 190 200
VHGASTSCNA DVFAYSASQV KKALEITKEL GGENYVFWGG REGYETLLNT
210 220 230 240 250
DMEFELDNFA RFLHMAVDYA KEIGFEGQLL IEPKPKEPTK HQYDFDVANV
260 270 280 290 300
LAFLRKYDLD KYFKVNIEAN HATLAFHDFQ HELRYARING VLGSIDANTG
310 320 330 340 350
DMLLGWDTDQ FPTDIRMTTL AMYEVIKMGG FDKGGLNFDA KVRRASFEPE
360 370 380 390 400
DLFLGHIAGM DAFAKGFKVA YKLVKDGVFD KFIEERYASY KDGIGADIVS
410 420 430
GKADFRSLEK YALEHSQIVN KSGRQELLES ILNQYLFAE
Length:439
Mass (Da):50,339
Last modified:July 27, 2011 - v1
Checksum:i322136CC5D7B94C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002739 Genomic DNA Translation: AEF18157.1
RefSeqiWP_013788885.1, NC_015555.1

Genome annotation databases

EnsemblBacteriaiAEF18157; AEF18157; Thexy_2149
KEGGitxy:Thexy_2149

Similar proteinsi

Entry informationi

Entry nameiF6BKS4_THEXL
AccessioniPrimary (citable) accession number: F6BKS4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 25, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported