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UniProtKB - F6BKC2 (F6BKC2_THEXL)

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Protein

Uronate isomerase

Gene

uxaC

Organism
Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-galacturonate = D-tagaturonate.UniRule annotationSAAS annotation
D-glucuronate = D-fructuronate.UniRule annotationSAAS annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

Complete GO annotation...

GO - Biological processi

Complete GO annotation...

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotationSAAS annotation (EC:5.3.1.12UniRule annotationSAAS annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:Thexy_2056Imported
OrganismiThermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)Imported
Taxonomic identifieri858215 [NCBI]
Taxonomic lineageiBacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Thermoanaerobacterium ›
Proteomesi
  • UP000007239 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi858215.Thexy_2056.

Structurei

3D structure databases

ProteinModelPortaliF6BKC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
KOiK01812.
OMAiFREMTTE.
OrthoDBiPOG091H07GL.

Family and domain databases

HAMAPiMF_00675. UxaC. 1 hit.
InterProiView protein in InterPro
IPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
PfamiView protein in Pfam
PF02614. UxaC. 1 hit.
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

F6BKC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNFMDDDFL LNNEVAVKLF HDYASKMPIF DFHCHLNPKD IYEDKKFKNI 
        60         70         80         90        100
TEVWLYGDHY KWRLMRSNGV DEKYITGDAD DYSKFLEFAK TMPMAIGNPV 
       110        120        130        140        150
FHWTHLELQR YFGVNELLNE KTAPMIWEKV NSVLESSEFS VRNIIKKSNV 
       160        170        180        190        200
KILCTTDDPT DSLEYHKLLM DDESFGVKVL PAFRPDKGIN IERDDFRDWV 
       210        220        230        240        250
KKLGEVSGKT IEDYEDYLDA LNSRIEYFDS LGCRLSDHAL DFVAYEESTK 
       260        270        280        290        300
SKVNEIFKKA LEGEELSKFE IDQYKTSVLQ FLARKYKEFG WAMQLHIAAL 
       310        320        330        340        350
RNTNTRMFRK LGPDTGYDAI NDVDIAQKVA KLLDSLDLTG SLPKTILYTL 
       360        370        380        390        400
NPKDNYVLAT IMGCFQGEGI PGKMQFGSAW WFNDNIDGMR EQMRTLANVG 
       410        420        430        440        450
LLSKFVGMVT DSRSFLSYPR HEYFRRILCN LIGEWVDRGE VPYDIDLLGK 
       460 
IVQDISYNNA VNYFGV
Length:466
Mass (Da):54,111
Last modified:July 27, 2011 - v1
Checksum:i8971B4794731613E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002739 Genomic DNA. Translation: AEF18069.1.
RefSeqiWP_013788799.1. NC_015555.1.

Genome annotation databases

EnsemblBacteriaiAEF18069; AEF18069; Thexy_2056.
KEGGitxy:Thexy_2056.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002739 Genomic DNA. Translation: AEF18069.1.
RefSeqiWP_013788799.1. NC_015555.1.

3D structure databases

ProteinModelPortaliF6BKC2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi858215.Thexy_2056.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEF18069; AEF18069; Thexy_2056.
KEGGitxy:Thexy_2056.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
KOiK01812.
OMAiFREMTTE.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

HAMAPiMF_00675. UxaC. 1 hit.
InterProiView protein in InterPro
IPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
PfamiView protein in Pfam
PF02614. UxaC. 1 hit.
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiF6BKC2_THEXL
AccessioniPrimary (citable) accession number: F6BKC2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 7, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.