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Protein

Uronate isomerase

Gene

uxaC

Organism
Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-galacturonate = D-tagaturonate.UniRule annotationSAAS annotation
D-glucuronate = D-fructuronate.UniRule annotationSAAS annotation

Pathway:ipentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciTXYL858215:GHCH-2133-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotationSAAS annotation (EC:5.3.1.12UniRule annotationSAAS annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:Thexy_2056Imported
OrganismiThermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)Imported
Taxonomic identifieri858215 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisThermoanaerobacterium
ProteomesiUP000007239 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi858215.Thexy_2056.

Structurei

3D structure databases

ProteinModelPortaliF6BKC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

KOiK01812.
OMAiIWHQCNE.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F6BKC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNFMDDDFL LNNEVAVKLF HDYASKMPIF DFHCHLNPKD IYEDKKFKNI
60 70 80 90 100
TEVWLYGDHY KWRLMRSNGV DEKYITGDAD DYSKFLEFAK TMPMAIGNPV
110 120 130 140 150
FHWTHLELQR YFGVNELLNE KTAPMIWEKV NSVLESSEFS VRNIIKKSNV
160 170 180 190 200
KILCTTDDPT DSLEYHKLLM DDESFGVKVL PAFRPDKGIN IERDDFRDWV
210 220 230 240 250
KKLGEVSGKT IEDYEDYLDA LNSRIEYFDS LGCRLSDHAL DFVAYEESTK
260 270 280 290 300
SKVNEIFKKA LEGEELSKFE IDQYKTSVLQ FLARKYKEFG WAMQLHIAAL
310 320 330 340 350
RNTNTRMFRK LGPDTGYDAI NDVDIAQKVA KLLDSLDLTG SLPKTILYTL
360 370 380 390 400
NPKDNYVLAT IMGCFQGEGI PGKMQFGSAW WFNDNIDGMR EQMRTLANVG
410 420 430 440 450
LLSKFVGMVT DSRSFLSYPR HEYFRRILCN LIGEWVDRGE VPYDIDLLGK
460
IVQDISYNNA VNYFGV
Length:466
Mass (Da):54,111
Last modified:July 27, 2011 - v1
Checksum:i8971B4794731613E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002739 Genomic DNA. Translation: AEF18069.1.
RefSeqiWP_013788799.1. NC_015555.1.

Genome annotation databases

EnsemblBacteriaiAEF18069; AEF18069; Thexy_2056.
KEGGitxy:Thexy_2056.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002739 Genomic DNA. Translation: AEF18069.1.
RefSeqiWP_013788799.1. NC_015555.1.

3D structure databases

ProteinModelPortaliF6BKC2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi858215.Thexy_2056.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEF18069; AEF18069; Thexy_2056.
KEGGitxy:Thexy_2056.

Phylogenomic databases

KOiK01812.
OMAiIWHQCNE.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciTXYL858215:GHCH-2133-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Thermoanaerobacterium xylanolyticum LX-11."
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Lu M., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hemme C., Woyke T.
    Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiF6BKC2_THEXL
AccessioniPrimary (citable) accession number: F6BKC2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 22, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.