uxaC

Functionⁱ

Catalytic activityⁱ

D-galacturonate = D-tagaturonate.UniRule annotationSAAS annotation

D-glucuronate = D-fructuronate.UniRule annotationSAAS annotation

Pathwayⁱ: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functionⁱ

glucuronate isomerase activity Source: UniProtKB-HAMAP

Complete GO annotation...

GO - Biological processⁱ

glucuronate catabolic process Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	IsomeraseUniRule annotationSAAS annotationImported

Molecular function

IsomeraseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

UniPathwayⁱ	UPA00246.

UniPathwayⁱ

UPA00246.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Uronate isomeraseUniRule annotationSAAS annotation (EC:5.3.1.12UniRule annotationSAAS annotation) Alternative name(s): Glucuronate isomeraseUniRule annotation Uronic isomeraseUniRule annotation
Gene namesⁱ	Name:uxaCUniRule annotation Ordered Locus Names:Thexy_2056Imported
Organismⁱ	Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)Imported
Taxonomic identifierⁱ	858215 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Thermoanaerobacterium › Thermoanaerobacterium xylanolyticum
Proteomesⁱ	UP000007239 Componentⁱ: Chromosome

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	858215.Thexy_2056.

STRINGⁱ

858215.Thexy_2056.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	F6BKC2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the uronate isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105D2H. Bacteria. COG1904. LUCA.
KEGG Orthology (KO) More...KOⁱ	K01812.
OMAⁱ	FREMTTE.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H07GL.

Family and domain databases

HAMAPⁱ	MF_00675. UxaC. 1 hit.
InterProⁱ	View protein in InterPro IPR032466. Metal_Hydrolase. IPR003766. Uronate_isomerase.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02614. UxaC. 1 hit.
SUPFAMⁱ	SSF51556. SSF51556. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

F6BKC2-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MKNFMDDDFL LNNEVAVKLF HDYASKMPIF DFHCHLNPKD IYEDKKFKNI 
        60         70         80         90        100
TEVWLYGDHY KWRLMRSNGV DEKYITGDAD DYSKFLEFAK TMPMAIGNPV 
       110        120        130        140        150
FHWTHLELQR YFGVNELLNE KTAPMIWEKV NSVLESSEFS VRNIIKKSNV 
       160        170        180        190        200
KILCTTDDPT DSLEYHKLLM DDESFGVKVL PAFRPDKGIN IERDDFRDWV 
       210        220        230        240        250
KKLGEVSGKT IEDYEDYLDA LNSRIEYFDS LGCRLSDHAL DFVAYEESTK 
       260        270        280        290        300
SKVNEIFKKA LEGEELSKFE IDQYKTSVLQ FLARKYKEFG WAMQLHIAAL 
       310        320        330        340        350
RNTNTRMFRK LGPDTGYDAI NDVDIAQKVA KLLDSLDLTG SLPKTILYTL 
       360        370        380        390        400
NPKDNYVLAT IMGCFQGEGI PGKMQFGSAW WFNDNIDGMR EQMRTLANVG 
       410        420        430        440        450
LLSKFVGMVT DSRSFLSYPR HEYFRRILCN LIGEWVDRGE VPYDIDLLGK 
       460 
IVQDISYNNA VNYFGV

Length:466

Mass (Da):54,111

Last modified:July 27, 2011 - v1

Checksum:ⁱ8971B4794731613E

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP002739 Genomic DNA. Translation: AEF18069.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_013788799.1. NC_015555.1.

Genome annotation databases

EnsemblBacteriaⁱ	AEF18069; AEF18069; Thexy_2056.
KEGGⁱ	txy:Thexy_2056.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP002739 Genomic DNA. Translation: AEF18069.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_013788799.1. NC_015555.1.

3D structure databases

ProteinModelPortalⁱ	F6BKC2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	858215.Thexy_2056.

STRINGⁱ

858215.Thexy_2056.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AEF18069; AEF18069; Thexy_2056.
KEGGⁱ	txy:Thexy_2056.

Phylogenomic databases

eggNOGⁱ	ENOG4105D2H. Bacteria. COG1904. LUCA.
KEGG Orthology (KO) More...KOⁱ	K01812.
OMAⁱ	FREMTTE.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H07GL.

Enzyme and pathway databases

UniPathwayⁱ	UPA00246.

UniPathwayⁱ

UPA00246.

Family and domain databases

HAMAPⁱ	MF_00675. UxaC. 1 hit.
InterProⁱ	View protein in InterPro IPR032466. Metal_Hydrolase. IPR003766. Uronate_isomerase.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02614. UxaC. 1 hit.
SUPFAMⁱ	SSF51556. SSF51556. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	F6BKC2_THEXL
Accessionⁱ	F6BKC2Primary (citable) accession number: F6BKC2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 27, 2011
	Last sequence update:	July 27, 2011
	Last modified:	June 7, 2017
	This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteomeImported

UniProtKB - F6BKC2 (F6BKC2_THEXL)

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Uronate isomerase

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Functionⁱ

Catalytic activityⁱ

Pathwayⁱ: pentose and glucuronate interconversion

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F6BKC2 (F6BKC2_THEXL)

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Uronate isomerase

uxaC

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: pentose and glucuronate interconversion

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

Pathwayⁱ: pentose and glucuronate interconversion

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ