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F6BFG0 (F6BFG0_THEXL) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain141 – 349209ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding176 – 23156ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3021Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3161Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3161Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3181Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
F6BFG0 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 49BAA9BE433F9008

FASTA36240,549
        10         20         30         40         50         60 
MDKLKVAVLF GGQSGEHEVS RVSATSIINN IDREKYEVYM VGITKRGQWY LYSGDVDKIA 

        70         80         90        100        110        120 
TGEWEKEAVP ALIGPSTMYK GIIAFKDKSY EFYPIDVVFP VLHGPNGEDG TVQGLMELLE 

       130        140        150        160        170        180 
MPYVGPNVLS SSLCMDKVFS KRIFLESGIP TPKFTVVYRK NLNDVDKHEK IRSEISEKIG 

       190        200        210        220        230        240 
YPCFVKPANM GSSVGISKVH NEGELIDALK IAAKYDRKII VEEGIDAREI ECSVLGNDNP 

       250        260        270        280        290        300 
EASVAGEIVP AHEFYDYDAK YFDEASKLFI PAPIPDAKME EIRELAIKAY TALDVRGMAR 

       310        320        330        340        350        360 
VDFLMDKNTG KVYLNELNTI PGFTQISMYP KLWEASGKPY SELIDELIQL ALSVHNEKCT 


NW 

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References

[1]"Complete sequence of Thermoanaerobacterium xylanolyticum LX-11."
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Lu M., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hemme C., Woyke T.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002739 Genomic DNA. Translation: AEF16238.1.
RefSeqYP_004469910.1. NC_015555.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEF16238; AEF16238; Thexy_0178.
GeneID10659476.
KEGGtxy:Thexy_0178.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycTXYL858215:GHCH-193-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF6BFG0_THEXL
AccessionPrimary (citable) accession number: F6BFG0
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 11, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)