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F6ACB0

- F6ACB0_PSEF1

UniProt

F6ACB0 - F6ACB0_PSEF1

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Psefu_2325

Organism
Pseudomonas fulva (strain 12-X)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei146 – 1461SubstrateUniRule annotation
    Sitei256 – 2561Critical for catalysisUniRule annotation
    Metal bindingi351 – 3511Magnesium or manganese
    Sitei421 – 4211Critical for catalysisUniRule annotation
    Binding sitei548 – 5481SubstrateUniRule annotation
    Metal bindingi549 – 5491Magnesium or manganese
    Metal bindingi553 – 5531Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciPFUL743720:GHQV-2358-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Psefu_2325Imported
    OrganismiPseudomonas fulva (strain 12-X)Imported
    Taxonomic identifieri743720 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000000686: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliF6ACB0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni133 – 1408Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.
    OMAiEEQRIGD.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F6ACB0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTRSKIIYT LTDEAPALAT YSLLPIVKAF TASSDIAVET RDISLAGRIL    50
    ALFPEFLTDA QKQGDHLAEL GALATTPEAN IIKLPNISAS VPQLKAAIKE 100
    LQSQGYALPD YPDADDSEQA RDIRSRYDKV KGSAVNPVLR EGNSDRRAPL 150
    SVKNYARKHP HKMGAWAADS KSHVAHMESG DFYGSEKAAL IDAKGSVKIE 200
    LIGADGSTTV LKEKTSVLAD EVLDCSVMSK KALRSFIAAQ IEDAKKQGVL 250
    FSVHLKATMM KVSDPIIFGQ IVAEFYKPAL EKHAAALQEA GFNLNNGIGD 300
    LYASIKKLPA DKQAEIEADI NAVYADRPAL AMVNSDKGIT NLHVPSDVIV 350
    DASMPAMIRD SGRMWNTAGE LQDAKAVIPD RCYAGIYQAV IEDCKANGAF 400
    NPTTMGSVPN VGLMAQKAEE YGSHDKTFQI QAAGVVRVSD ANGKVLMEQK 450
    VEEGDIFRMC QTKDAPIQDW VKLAVNRARL SNTPAVFWLD PARAHDAEMI 500
    KKVEKYLKDH DTSGLDIRIL APVDAIKFSL ARIREGKDTI SVTGNVLRDY 550
    LTDLFPIMEL GTSAKMLSIV PLMNGGGLFE TGAGGSAPKH VQQLVEENFL 600
    RWDSLGEFLA LAASLEHLGN TYDNPKALVL SKTLDQATGQ FLDNDKSPAR 650
    KVGGIDNRGS HFYLALYWAQ ALAAQSEDAA LKAQFAPLAK TLTDNEAKIV 700
    AELGAVQGKP ADIGGYYAPN KELTEKVMRP SATLNAALAS LA 742
    Length:742
    Mass (Da):80,113
    Last modified:July 27, 2011 - v1
    Checksum:iD1EDD95F98694A49
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002727 Genomic DNA. Translation: AEF22292.1.
    RefSeqiWP_013791421.1. NC_015556.1.
    YP_004474386.1. NC_015556.1.

    Genome annotation databases

    EnsemblBacteriaiAEF22292; AEF22292; Psefu_2325.
    GeneIDi10657407.
    KEGGipfv:Psefu_2325.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002727 Genomic DNA. Translation: AEF22292.1 .
    RefSeqi WP_013791421.1. NC_015556.1.
    YP_004474386.1. NC_015556.1.

    3D structure databases

    ProteinModelPortali F6ACB0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEF22292 ; AEF22292 ; Psefu_2325 .
    GeneIDi 10657407.
    KEGGi pfv:Psefu_2325.

    Phylogenomic databases

    KOi K00031.
    OMAi EEQRIGD.

    Enzyme and pathway databases

    BioCyci PFUL743720:GHQV-2358-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 12-XImported.

    Entry informationi

    Entry nameiF6ACB0_PSEF1
    AccessioniPrimary (citable) accession number: F6ACB0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3