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F6ACB0

- F6ACB0_PSEF1

UniProt

F6ACB0 - F6ACB0_PSEF1

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Protein
Submitted name: Isocitrate dehydrogenase, NADP-dependent
Gene
Psefu_2325
Organism
Pseudomonas fulva (strain 12-X)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei146 – 1461Substrate By similarityUniRule annotation
Sitei256 – 2561Critical for catalysis By similarity
Metal bindingi351 – 3511Magnesium or manganese By similarityUniRule annotation
Sitei421 – 4211Critical for catalysis By similarityUniRule annotation
Binding sitei548 – 5481Substrate By similarityUniRule annotation
Metal bindingi549 – 5491Magnesium or manganese By similarityUniRule annotation
Metal bindingi553 – 5531Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPFUL743720:GHQV-2358-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Psefu_2325Imported
OrganismiPseudomonas fulva (strain 12-X)Imported
Taxonomic identifieri743720 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000686: Chromosome

Structurei

3D structure databases

ProteinModelPortaliF6ACB0.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 1408Substrate binding By similarityUniRule annotation

Phylogenomic databases

KOiK00031.
OMAiEEQRIGD.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

F6ACB0-1 [UniParc]FASTAAdd to Basket

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MTTRSKIIYT LTDEAPALAT YSLLPIVKAF TASSDIAVET RDISLAGRIL    50
ALFPEFLTDA QKQGDHLAEL GALATTPEAN IIKLPNISAS VPQLKAAIKE 100
LQSQGYALPD YPDADDSEQA RDIRSRYDKV KGSAVNPVLR EGNSDRRAPL 150
SVKNYARKHP HKMGAWAADS KSHVAHMESG DFYGSEKAAL IDAKGSVKIE 200
LIGADGSTTV LKEKTSVLAD EVLDCSVMSK KALRSFIAAQ IEDAKKQGVL 250
FSVHLKATMM KVSDPIIFGQ IVAEFYKPAL EKHAAALQEA GFNLNNGIGD 300
LYASIKKLPA DKQAEIEADI NAVYADRPAL AMVNSDKGIT NLHVPSDVIV 350
DASMPAMIRD SGRMWNTAGE LQDAKAVIPD RCYAGIYQAV IEDCKANGAF 400
NPTTMGSVPN VGLMAQKAEE YGSHDKTFQI QAAGVVRVSD ANGKVLMEQK 450
VEEGDIFRMC QTKDAPIQDW VKLAVNRARL SNTPAVFWLD PARAHDAEMI 500
KKVEKYLKDH DTSGLDIRIL APVDAIKFSL ARIREGKDTI SVTGNVLRDY 550
LTDLFPIMEL GTSAKMLSIV PLMNGGGLFE TGAGGSAPKH VQQLVEENFL 600
RWDSLGEFLA LAASLEHLGN TYDNPKALVL SKTLDQATGQ FLDNDKSPAR 650
KVGGIDNRGS HFYLALYWAQ ALAAQSEDAA LKAQFAPLAK TLTDNEAKIV 700
AELGAVQGKP ADIGGYYAPN KELTEKVMRP SATLNAALAS LA 742
Length:742
Mass (Da):80,113
Last modified:July 27, 2011 - v1
Checksum:iD1EDD95F98694A49
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002727 Genomic DNA. Translation: AEF22292.1.
RefSeqiWP_013791421.1. NC_015556.1.
YP_004474386.1. NC_015556.1.

Genome annotation databases

EnsemblBacteriaiAEF22292; AEF22292; Psefu_2325.
GeneIDi10657407.
KEGGipfv:Psefu_2325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002727 Genomic DNA. Translation: AEF22292.1 .
RefSeqi WP_013791421.1. NC_015556.1.
YP_004474386.1. NC_015556.1.

3D structure databases

ProteinModelPortali F6ACB0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEF22292 ; AEF22292 ; Psefu_2325 .
GeneIDi 10657407.
KEGGi pfv:Psefu_2325.

Phylogenomic databases

KOi K00031.
OMAi EEQRIGD.

Enzyme and pathway databases

BioCyci PFUL743720:GHQV-2358-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 12-X.

Entry informationi

Entry nameiF6ACB0_PSEF1
AccessioniPrimary (citable) accession number: F6ACB0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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