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F6A8G7 (F6A8G7_PSEF1) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-isopropylmalate dehydratase small subunit HAMAP-Rule MF_01031
EC=4.2.1.33 HAMAP-Rule MF_01031
Alternative name(s):
Alpha-IPM isomerase HAMAP-Rule MF_01031
Isopropylmalate isomerase HAMAP-Rule MF_01031
Gene names
Name:leuD HAMAP-Rule MF_01031
Ordered Locus Names:Psefu_3074
OrganismPseudomonas fulva (strain 12-X) [Complete proteome] [HAMAP] EMBL AEF23038.1
Taxonomic identifier743720 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate By similarity. SAAS SAAS004431 HAMAP-Rule MF_01031

Catalytic activity

(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate. SAAS SAAS004431 HAMAP-Rule MF_01031

Pathway

Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4. SAAS SAAS004431 HAMAP-Rule MF_01031

Subunit structure

Heterodimer of LeuC and LeuD By similarity. SAAS SAAS004431 HAMAP-Rule MF_01031

Sequence similarities

Belongs to the LeuD family. LeuD type 1 subfamily. HAMAP-Rule MF_01031

Sequences

Sequence LengthMass (Da)Tools
F6A8G7 [UniParc].

Last modified July 27, 2011. Version 1.
Checksum: 2B521DDBC18A2E28

FASTA21524,328
        10         20         30         40         50         60 
MKAFTQHTGL VCPLDRANVD TDQIIPKQFL KSIKRTGFGP NLFDEWRYLD VGQPNQDNSK 

        70         80         90        100        110        120 
RPINKDFVLN FPRYQGASVL LARENFGCGS SREHAPWALD EYGFRTVIAP SFADIFFNNS 

       130        140        150        160        170        180 
FKNGLLPIIL KAEEVDALFE QAEASEGYQL TVDLEAQTVT RPDGVQYSFE VDAFRKHCLL 

       190        200        210 
NGLDDIGLTL QDAEAIRAFE VGYQQRQPWL FGAVK

« Hide

References

[1]"Complete sequence of Pseudomonas fulva 12-X."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Pagani I., Davenport K., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Lcollab F.I., Woyke T.
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 12-X.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002727 Genomic DNA. Translation: AEF23038.1.
RefSeqYP_004475132.1. NC_015556.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEF23038; AEF23038; Psefu_3074.
GeneID10657970.
KEGGpfv:Psefu_3074.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01704.
OMAYQDNSKR.

Enzyme and pathway databases

BioCycPFUL743720:GHQV-3129-MONOMER.
UniPathwayUPA00048; UER00071.

Family and domain databases

Gene3D3.20.19.10. 1 hit.
HAMAPMF_01031. LeuD_type1.
InterProIPR004431. 3-IsopropMal_deHydase_ssu.
IPR015937. Acoase/IPM_deHydtase.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR000573. AconitaseA/IPMdHydase_ssu_swvl.
[Graphical view]
PANTHERPTHR11670. PTHR11670. 1 hit.
PTHR11670:SF2. PTHR11670:SF2. 1 hit.
PfamPF00694. Aconitase_C. 1 hit.
[Graphical view]
SUPFAMSSF52016. Aconitase/3IPM_dehydase_swvl. 1 hit.
TIGRFAMsTIGR00171. leuD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF6A8G7_PSEF1
AccessionPrimary (citable) accession number: F6A8G7
Entry history
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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