F5ZUC2 (F5ZUC2_SALTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP-Rule MF_00033
EC=2.4.1.227 HAMAP-Rule MF_00033

Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase HAMAP-Rule MF_00033

Gene names

Name:	murG HAMAP-Rule MF_00033 EMBL AEF06064.1
Ordered Locus Names:	STMUK_0130 EMBL AEF06064.1

Organism

Salmonella typhimurium (strain ATCC 68169 / UK-1) [Complete proteome] [HAMAP]

Taxonomic identifier

990282 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella typhimurium

Protein attributes

Sequence length	355 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP-Rule MF_00033 SAAS SAAS006009
Catalytic activity	UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP-Rule MF_00033 SAAS SAAS006009
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00033 SAAS SAAS006009
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_00033.
Sequence similarities	Belongs to the glycosyltransferase 28 family. MurG subfamily. HAMAP-Rule MF_00033

Ontologies

Keywords
Biological process	Cell cycle Cell division HAMAP-Rule MF_00033 SAAS SAAS006009 Cell shape Cell wall biogenesis/degradation HAMAP-Rule MF_00033 SAAS SAAS006009 Peptidoglycan synthesis HAMAP-Rule MF_00033 SAAS SAAS006009
Cellular component	Cell inner membrane HAMAP-Rule MF_00033 Cell membrane Membrane
Molecular function	Glycosyltransferase HAMAP-Rule MF_00033 SAAS SAAS006009 EMBL AEF06064.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	UDP-N-acetylgalactosamine biosynthetic process Inferred from electronic annotation. Source: InterPro cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW lipid glycosylation Inferred from electronic annotation. Source: HAMAP peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F5ZUC2 [UniParc]. Last modified July 27, 2011. Version 1. Checksum: DE338E433C134809	FASTA	355	37,863
	10 20 30 40 50 60 MSGQPKRLMV MAGGTGGHVF PGLAVAHHLM AQGWQVRWLG TADRMEADLV PKHGIDIDFI 70 80 90 100 110 120 RISGLRGKGV KALLAAPLRI FNAWRQARAI MKRFKPDVVL GMGGYVSGPG GLAAWSLGIP 130 140 150 160 170 180 VVLHEQNGIA GLTNQWLAKI ATTVMQAFPG AFPNAEVVGN PVRTDVLALP LPQVRLAGRD 190 200 210 220 230 240 GPIRVLVVGG SQGARVLNQT MPQVAARLGD TVTIWHQSGK GAQLTVEQAY AGAGQPQHKV 250 260 270 280 290 300 TEFIDDMAAA YAWADVVVCR SGALTVSEIA AAGLPAIFVP FQHKDRQQYW NALPLENAGA 310 320 330 340 350 AKIFEQPQFT VEAVADTLAG WSREALLTMA ERARAVSIPD ATERVASEVS RVART

References

[1]

"Complete genome sequence of the universal killer Salmonella enterica serovar typhimurium UK-1 (ATCC 68169)." Luo Y., Kong Q., Yang J., Golden G., Wanda S.Y., Jensen R.V., Ernst P.B., Curtiss R. III. J. Bacteriol. 193:4035-4036(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 68169 / UK-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002614 Genomic DNA. Translation: AEF06064.1.
RefSeq	YP_005250698.1. NC_016863.1.
3D structure databases
ProteinModelPortal	F5ZUC2.
SMR	F5ZUC2. Positions 6-354.
ModBase	Search...
Proteomic databases
PRIDE	F5ZUC2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEF06064; AEF06064; STMUK_0130.
GeneID	11834268.
KEGG	sej:STMUK_0130.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K02563.
Enzyme and pathway databases
UniPathway	UPA00219.
Family and domain databases
HAMAP	MF_00033. MurG.
InterPro	IPR006009. GlcNAc_MurG. IPR004276. Glyco_trans_28. IPR007235. Glyco_trans_28_C. [Graphical view]
PANTHER	PTHR21015:SF22. PTHR21015:SF22. 1 hit.
Pfam	PF04101. Glyco_tran_28_C. 1 hit. PF03033. Glyco_transf_28. 1 hit. [Graphical view]
TIGRFAMs	TIGR01133. murG. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F5ZUC2_SALTU

Accession

Primary (citable) accession number: F5ZUC2

Entry history

Integrated into UniProtKB/TrEMBL:	July 27, 2011
Last sequence update:	July 27, 2011
Last modified:	April 3, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)