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F5Z778

- F5Z778_ALTSS

UniProt

F5Z778 - F5Z778_ALTSS

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Protein

Choline dehydrogenase

Gene

ambt_06940

Organism
Alteromonas sp. (strain SN2)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.SAAS annotation

Catalytic activityi

Betaine aldehyde + NAD+ + H2O = betaine + NADH.SAAS annotation
Choline + acceptor = betaine aldehyde + reduced acceptor.SAAS annotation

Cofactori

FAD.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. choline dehydrogenase activity Source: UniProtKB-EC
  2. flavin adenine dinucleotide binding Source: InterPro

GO - Biological processi

  1. glycine betaine biosynthetic process from choline Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseSAAS annotationImported

Keywords - Ligandi

FADUniRule annotationSAAS annotation, Flavoprotein, NADSAAS annotation

Enzyme and pathway databases

BioCyciASP715451:GHV1-1389-MONOMER.
UniPathwayiUPA00529; UER00385.

Names & Taxonomyi

Protein namesi
Recommended name:
Choline dehydrogenaseUniRule annotation (EC:1.1.99.1UniRule annotation)
Gene namesi
Ordered Locus Names:ambt_06940Imported
OrganismiAlteromonas sp. (strain SN2)Imported
Taxonomic identifieri715451 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeAlteromonas
ProteomesiUP000000683: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the GMC oxidoreductase family.UniRule annotation

Phylogenomic databases

KOiK00108.

Family and domain databases

InterProiIPR011533. BetA.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
PfamiPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsiTIGR01810. betA. 1 hit.
PROSITEiPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5Z778-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKQAYDYII VGAGSAGCVL ANRLSEDANN NVLLLETGGS DKSIFIKMPT
60 70 80 90 100
ALSIPMNTDK YAWQFHTEEE PFLDNRKMHC PRGKVLGGSS SINGMVYVRG
110 120 130 140 150
HAKDFDEWEE HGAQGWNYQA CLPYFQKAES FYLGNDDYRG GKGPLGVNNG
160 170 180 190 200
NEMANPLYTA FIEAGKEAGY ATTADYNAAQ QEGFGPMHMT VKDGVRSSAS
210 220 230 240 250
REYLDPVKSR KNLTLVTGAL AEKVILEGKK AVGVQYSVNG KRVTAKANKE
260 270 280 290 300
VVLSAGSIGS PHLLQLSGIG DSETLKAAGV DVKHHLPGVG QNLQDHLEFY
310 320 330 340 350
FQYKCKQPIT LNGKLGLISK GLIGARWMFT RKGLGATNHF ESCAFIRSKP
360 370 380 390 400
GVEWPDIQYH FLPAAMRYDG LSAFDGHGFQ VHVGHNKPKS RGAVTIKTAN
410 420 430 440 450
PTDAPKIQFN YLQHQDDIEG FRACVRLTRE IIEQSAFDDY REDEIQPGKH
460 470 480 490 500
IQTDEEIDAF VRQAVESAYH PSCSCKMGED AMAVVNSNTQ VHGIESLRVV
510 520 530 540 550
DSSIFPTVPN GNLNAPTIMV AEKAADLILG KPALAHSPVN VATSNNWETV

QRNSTI
Length:556
Mass (Da):60,849
Last modified:July 27, 2011 - v1
Checksum:iFE454CC1D0FF49A9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002339 Genomic DNA. Translation: AEF02921.1.
RefSeqiWP_013783861.1. NC_015554.1.
YP_004466723.1. NC_015554.1.

Genome annotation databases

EnsemblBacteriaiAEF02921; AEF02921; ambt_06940.
GeneIDi10654551.
KEGGialt:ambt_06940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002339 Genomic DNA. Translation: AEF02921.1 .
RefSeqi WP_013783861.1. NC_015554.1.
YP_004466723.1. NC_015554.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEF02921 ; AEF02921 ; ambt_06940 .
GeneIDi 10654551.
KEGGi alt:ambt_06940.

Phylogenomic databases

KOi K00108.

Enzyme and pathway databases

UniPathwayi UPA00529 ; UER00385 .
BioCyci ASP715451:GHV1-1389-MONOMER.

Family and domain databases

InterProi IPR011533. BetA.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view ]
Pfami PF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsi TIGR01810. betA. 1 hit.
PROSITEi PS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the polycyclic aromatic hydrocarbon-degrading bacterium Alteromonas sp. strain SN2."
    Jin H.M., Jeong H., Moon E.J., Math R.K., Lee K., Kim H.J., Jeon C.O., Oh T.K., Kim J.F.
    J. Bacteriol. 193:4292-4293(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SN2Imported.

Entry informationi

Entry nameiF5Z778_ALTSS
AccessioniPrimary (citable) accession number: F5Z778
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: October 1, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3