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F5YBY1

- F5YBY1_TREAZ

UniProt

F5YBY1 - F5YBY1_TREAZ

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Protein

Lysine--tRNA ligase

Gene

lysS

Organism
Treponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. lysine-tRNA ligase activity Source: UniProtKB-HAMAP
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. lysyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotation, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTAZO545695:GHPL-515-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine--tRNA ligaseUniRule annotation (EC:6.1.1.6UniRule annotation)
Alternative name(s):
Lysyl-tRNA synthetaseUniRule annotation
Gene namesi
Name:lysSUniRule annotationImported
Ordered Locus Names:TREAZ_1825Imported
OrganismiTreponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9)Imported
Taxonomic identifieri545695 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000009222: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF5YBY1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi42 – 509"HIGH" regionUniRule annotation
Motifi294 – 2985"KMSKS" regionUniRule annotation

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

KOiK04566.
OMAiWPARWSI.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
2.30.30.300. 1 hit.
3.40.50.620. 3 hits.
HAMAPiMF_00177. Lys_tRNA_synth_class1.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR023386. Lys-tRNA-ligase_insertion.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF01921. tRNA-synt_1f. 1 hit.
[Graphical view]
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00467. lysS_arch. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5YBY1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEKKNEASGA QASAHWADET AAKILREKGD KELYTCASGI TPSGTVHIGN
60 70 80 90 100
FREIISTDLV VRALRDKGKK VRFIYSWDDY DVFRKVPKNM PQQEALNGHL
110 120 130 140 150
RFPITMVPDP WGRDSSYARH HEVDIETVLP KVGVHPEFLY QAENYRSSKY
160 170 180 190 200
AEGIRKALEH REALKNILDK FRDEEHKIQG EWWPVSAFCS ACNKDDTEID
210 220 230 240 250
SWDGEWGVTY HCNSCGHKET ADIRTAKGIK LFWRIDWPMR WEYEKVDFEP
260 270 280 290 300
AGKDHHSQGG SFDTAKHVCK DVYDWDAPVT FRYDFIGTKG LPGKMSSSSG
310 320 330 340 350
NVITIEDVLN VYTPEVARYL FAGTRPNTEF TISFDLDVIK IYEDYDKTER
360 370 380 390 400
IAFKAEPAKD EAVYQKERRI YELSQAAVTA EGKTKMPEIM PFQVPFRHLC
410 420 430 440 450
NLIQIADGDI DKAIASIANL KPEQIPALKA RAACAKYWID ECAPEEFRFK
460 470 480 490 500
LREPGETSDL ADNEKAAIKQ LRDEVISKID SFTDDKGCAE AIYKIAEAQG
510 520 530 540
MEGKALFRAA YQALIGKDQG PRLANFLRSI NKDRLLGILK AY
Length:542
Mass (Da):61,709
Last modified:July 27, 2011 - v1
Checksum:i34935944DCC4AD3C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001841 Genomic DNA. Translation: AEF80924.1.
RefSeqiYP_004526094.1. NC_015577.1.

Genome annotation databases

EnsemblBacteriaiAEF80924; AEF80924; TREAZ_1825.
GeneIDi10678131.
KEGGitaz:TREAZ_1825.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001841 Genomic DNA. Translation: AEF80924.1 .
RefSeqi YP_004526094.1. NC_015577.1.

3D structure databases

ProteinModelPortali F5YBY1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEF80924 ; AEF80924 ; TREAZ_1825 .
GeneIDi 10678131.
KEGGi taz:TREAZ_1825.

Phylogenomic databases

KOi K04566.
OMAi WPARWSI.

Enzyme and pathway databases

BioCyci TAZO545695:GHPL-515-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
2.30.30.300. 1 hit.
3.40.50.620. 3 hits.
HAMAPi MF_00177. Lys_tRNA_synth_class1.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR023386. Lys-tRNA-ligase_insertion.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF01921. tRNA-synt_1f. 1 hit.
[Graphical view ]
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00467. lysS_arch. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Treponema azotonutricium strain ZAS-9."
    Tetu S.G., Matson E., Ren Q., Seshadri R., Elbourne L., Hassan K.A., Durkin A., Radune D., Mohamoud Y., Shay R., Jin S., Zhang X., Lucey K., Ballor N.R., Ottesen E., Rosenthal R., Allen A., Leadbetter J.R., Paulsen I.T.
    Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-888 / DSM 13862 / ZAS-9Imported.

Entry informationi

Entry nameiF5YBY1_TREAZ
AccessioniPrimary (citable) accession number: F5YBY1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: October 29, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3