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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

TREAZ_3439

Organism
Treponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

BioCyciTAZO545695:G1GXX-2430-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:TREAZ_3439Imported
OrganismiTreponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9)Imported
Taxonomic identifieri545695 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000009222 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi545695.TREAZ_3439

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 77Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini134 – 171Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4107QKR Bacteria
COG0508 LUCA
KOiK00627
OMAiSWRLGCD
OrthoDBiPOG091H04EL

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR003016 2-oxoA_DH_lipoyl-BS
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS00189 LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

F5Y7S9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHVLIMPRQ GNTVESCIIG EWKVKEGDTV QADTPVCVVE TDKATFEVPS
60 70 80 90 100
GASGTVLKIF HSQGDDVPVL QPIMVVGNPG ENWEAAVPGG ASAASAAQAA
110 120 130 140 150
PAAASGATSA ALAVSVPAVE AVQAPAPQTE GHLAASPRAK KLADAEAVDI
160 170 180 190 200
RTLGGSGPGG RIIEVDVAAA LAARPPLTEA AKDELRKRIA VGLPAGTAGQ
210 220 230 240 250
GTGIGGRFTL GDLASGGAGS GAVVGTSPPA ASSAAPAPGG FTDIPIKGIR
260 270 280 290 300
KVIADQMMNS HTNTAAFTLN TSASVVNLQK LRARFKASDP ELGLSKITLN
310 320 330 340 350
DLVLFAASRV LPLYTYMNAH RLDGVVRAYN DVQLGVAVST PRGLMVPVMR
360 370 380 390 400
NADKLSLVQI SQKARELAEA CRSGSISPDD LHGSTFTVTN LGNTGIESFS
410 420 430 440 450
PVINIPEVAI MGVCGISPKA AETSPGVYEI LPHLGLSLTI DHAVVDGAPA
460 470
AEFLKAFAGA IRDIDIWVAK
Length:470
Mass (Da):47,866
Last modified:July 27, 2011 - v1
Checksum:i589E6067A6823D25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001841 Genomic DNA Translation: AEF81923.1
RefSeqiWP_015712133.1, NC_015577.1

Genome annotation databases

EnsemblBacteriaiAEF81923; AEF81923; TREAZ_3439
KEGGitaz:TREAZ_3439

Similar proteinsi

Entry informationi

Entry nameiF5Y7S9_TREAZ
AccessioniPrimary (citable) accession number: F5Y7S9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health