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F5Y3D8

- F5Y3D8_RAMTT

UniProt

F5Y3D8 - F5Y3D8_RAMTT

Protein

Alanine racemase

Gene

alr2

Organism
Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei47 – 471Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei142 – 1421SubstrateUniRule annotation
    Active sitei268 – 2681Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei316 – 3161Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciRTAT365046:GHCU-166-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alr2Imported
    Ordered Locus Names:Rta_01610Imported
    OrganismiRamlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310)Imported
    Taxonomic identifieri365046 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeRamlibacter
    ProteomesiUP000008385: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei47 – 471N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF5Y3D8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.
    OMAiYGHGLER.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F5Y3D8-1 [UniParc]FASTAAdd to Basket

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    MPKSPRHPRD YPMPRPIQAT IHTESLRHNL ARMRRAAPDA RAWGVVKANA    50
    YGHGIERAFE GLRGADGFAL LDLQEAERVR ALGWRGPILL LEGVFEPRDL 100
    ELCSRLSLWH TVHCDEQIDM LAAHKTQLPH RVFLKMNSGM NRLGFAPHRY 150
    RAAWARLDAL PQVDEITLMT HFSDADTARG IGHQARVFAE TTRDLPGERT 200
    LGNSAAALRF GQEAAVRADW VRPGIAVYGS APDFPEHDIA HWGLQPTMTL 250
    ASRLIAVQQL RPGDTVGYGS SFTAEAPLRI GVVACGYADG YPRHGPTGTP 300
    VLVDGVRTRL VGRVSMDMVT VDLTPVPQAG FGSEATLWGR AANGAVLPID 350
    EVARAAGTVG YELMCAVAPR VPFAVD 376
    Length:376
    Mass (Da):41,032
    Last modified:July 27, 2011 - v1
    Checksum:i9BFD8F3AA623FA86
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000245 Genomic DNA. Translation: AEG91225.1.
    RefSeqiYP_004617244.1. NC_015677.1.

    Genome annotation databases

    EnsemblBacteriaiAEG91225; AEG91225; Rta_01610.
    GeneIDi10830717.
    KEGGirta:Rta_01610.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000245 Genomic DNA. Translation: AEG91225.1 .
    RefSeqi YP_004617244.1. NC_015677.1.

    3D structure databases

    ProteinModelPortali F5Y3D8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEG91225 ; AEG91225 ; Rta_01610 .
    GeneIDi 10830717.
    KEGGi rta:Rta_01610.

    Phylogenomic databases

    KOi K01775.
    OMAi YGHGLER.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci RTAT365046:GHCU-166-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome of the cyst-dividing bacterium Ramlibacter tataouinensis."
      Barakat M., Ortet P., De Luca G., Jourlin-Castelli C., Ansaldi M., Py B., Fichant G., Coutinho P., Voulhoux R., Bastien O., Roy S., Marechal E., Henrissat B., Quentin Y., Noirot P., Filloux A., Mejean V., DuBow M., Barras F., Heulin T.
      Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310Imported.

    Entry informationi

    Entry nameiF5Y3D8_RAMTT
    AccessioniPrimary (citable) accession number: F5Y3D8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 27, 2011
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3