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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus pasteurianus (strain ATCC 43144 / JCM 5346 / CDC 1723-81)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei604 – 6041UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSPAS981540:GJYA-1479-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:SGPB_1409Imported
OrganismiStreptococcus pasteurianus (strain ATCC 43144 / JCM 5346 / CDC 1723-81)Imported
Taxonomic identifieri981540 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000007946 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5X2D8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIKKLENNS TQSIITEEVK VLKDLLDEAT HQMVGDEVFA KIQNIVELSA
60 70 80 90 100
SDEYVKLEKL VAQLTNDEMV VVSRYFSILP LLINISEDVD FAYEINYQNN
110 120 130 140 150
TNQDYLGKLS LTVDMVSESE NSKEILENVN VVPVLTAHPT QVQRKTVLEL
160 170 180 190 200
TNHIHDLLRK YRDVRAGVVN RDKWYTDLRR YIEIIMQTDI IREKKLKVKN
210 220 230 240 250
EITNVMEYYN TSLIQAITKL TSEYKRLAAE KGIDLEDPKP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAE TLRLSATVQS EVIINYYIEK LTGLYRTFSL STTLTNISPE
310 320 330 340 350
VEKLAELSSD KSIYRENEPY RKAFNYIQSK LIQTLIELKA SPAISQRVLE
360 370 380 390 400
SSNSISSDVY TSTNNASVIT KYLQTKFSKV SSELQEEIPS YKTAKEFKDD
410 420 430 440 450
LLIIKQSLLD NGDDALLIGD FSELLQAVEV FGFYLAMIDM RQDSSVNEAC
460 470 480 490 500
VAELLKSANI VEDYSALSEE EKVKVLLKEL QEDPRTLSST NAEKSEQLQK
510 520 530 540 550
ELAIFQTARY LKDKLGDEVI KQHIISHTES VSDMFELAIM LKEVGLLDNQ
560 570 580 590 600
KARVQIVPLF ETIEDLENSR AIMEEYLDYD IVRRWVSANK GYQEIMLGYS
610 620 630 640 650
DSNKDGGYLS SVWTLYKAQN ELTRIGSERG IKVTFIHGRG GTVGRGGGPS
660 670 680 690 700
YEAITSQPFG SIKDRIRLTE QGEIIENKYG NKDVAYYNLE MLVSATIDRI
710 720 730 740 750
VTRMITNPDE IDDFRATMDG IVTYSNSVYR DLVFGNPHFY DYFFEATPIK
760 770 780 790 800
EVSSLNIGSR PAARKTITEI SGLRAIPWVF SWSQSRIMFP GWYGVGSAFK
810 820 830 840 850
NFIDAEEGNL AKLQHMYEKW PFFHSLLSNV DMVLSKSNMN IAFQYAQLAE
860 870 880 890 900
SEEVRDVFNT ILDEWQLTKN VILAIEKHED LLEENPSLQA SLDYRLPYFN
910 920 930 940
VLNYIQIELI KRLRHEELDE DYEKLIHTTI NGIATGLRNS G
Length:941
Mass (Da):107,545
Last modified:July 27, 2011 - v1
Checksum:iE37C4E2CF4594FB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012054 Genomic DNA. Translation: BAK30447.1.
RefSeqiWP_013852088.1. NC_015600.1.

Genome annotation databases

EnsemblBacteriaiBAK30447; BAK30447; SGPB_1409.
KEGGistb:SGPB_1409.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012054 Genomic DNA. Translation: BAK30447.1.
RefSeqiWP_013852088.1. NC_015600.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAK30447; BAK30447; SGPB_1409.
KEGGistb:SGPB_1409.

Phylogenomic databases

KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciSPAS981540:GJYA-1479-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequencing and comparative genome analysis of two pathogenic Streptococcus gallolyticus subspecies: genome plasticity, adaptation and virulence."
    Lin I.-H., Liu T.-T., Teng Y.-T., Wu H.-L., Liu Y.-M., Wu K.-M., Chang C.-H., Hsu M.-T.
    PLoS ONE 6:E20519-E20519(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43144 / JCM 5346 / CDC 1723-81Imported.

Entry informationi

Entry nameiF5X2D8_STRPX
AccessioniPrimary (citable) accession number: F5X2D8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 22, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.