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F5HCP9 (F5HCP9_CRYNB) Unreviewed, UniProtKB/TrEMBL

Last modified October 3, 2012. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate By similarity. PIRNR PIRNR000858

Catalytic activity

Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA. PIRNR PIRNR000858

Pathway

Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1. PIRNR PIRNR000858

Sequence similarities

Belongs to the 3-oxoacid CoA-transferase family. PIRNR PIRNR000858

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
   Cellular componentMitochondrion PIRNR PIRNR000858
   Molecular functionTransferase PIRNR PIRNR000858
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processketone body catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentmitochondrion

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_function3-oxoacid CoA-transferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
F5HCP9 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: E7EDA762FFA2F865

FASTA56159,866
        10         20         30         40         50         60 
MIRTALPTTR ALARSRVLHR AAALARPGAI TASRYINTEP VKGSPSDLKS VPSQGTHGRS 

        70         80         90        100        110        120 
RITPSEKSKV WPDAKTAIRD IKNGQTILSA GFGLCGTAET IIKAMRESDL KDLTVVSNNA 

       130        140        150        160        170        180 
GNAGTYGLSP LITSKQIKKM ILSYLGTNKG LQDAYLSGEI EIELCPQGTI AERLRAAGAG 

       190        200        210        220        230        240 
MPGFFTRTGA GTDVETGGIP QKWSKPDADG KQTIAIPGVK KDTQVFDGKK FLFEPAIHGD 

       250        260        270        280        290        300 
VAVFRAWKVD KAGNCVFRYT TRTFGPLVAR AAKLSIVEAE NIVEIGELDP MEIDLPGIFV 

       310        320        330        340        350        360 
DRVVPATEDK QIEIFTTREE NENVSPSSGE ETSVNKSVGQ AQREKIAQRA GKELYDGAYV 

       370        380        390        400        410        420 
NLGVGIPVLA ANYLPDGMKV WVQSENGILG MGPYPTKEEV DADIINAGKE TVTLVPGASV 

       430        440        450        460        470        480 
FDSSESFGMI RGGHVDVSIL GAMEVSANGD LANYMIPGKL VKGMGGAMDL VSNPDETKIV 

       490        500        510        520        530        540 
VVTTHTDKHG RPKIVESCKL PLTGVSVVSR IITDLAVFDV DRTGQNGGGL ELIEIAEGVS 

       550        560 
LEEVQEKTGA TFKVREPLGR F

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AAEY01000044 Genomic DNA. Translation: EAL18836.1.
RefSeqXP_773483.1. XM_768390.1.

3D structure databases

ProteinModelPortalF5HCP9.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4938050.
KEGGcnb:CNBI0970.

Phylogenomic databases

KOK01027.

Enzyme and pathway databases

UniPathwayUPA00929; UER00894.

Family and domain databases

InterProIPR012791. 3-oxoacid_CoA-transf_B.
IPR014388. 3-oxoacid_CoA-transferase.
IPR004165. CoA_trans_fam_I.
[Graphical view]
PANTHERPTHR13707. PTHR13707. 1 hit.
PfamPF01144. CoA_trans. 2 hits.
[Graphical view]
PIRSFPIRSF000858. SCOT-t. 1 hit.
SMARTSM00882. CoA_trans. 2 hits.
[Graphical view]
TIGRFAMsTIGR02428. pcaJ_scoB_fam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF5HCP9_CRYNB
AccessionPrimary (citable) accession number: F5HCP9
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: October 3, 2012
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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