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Protein

Capsid vertex component 1

Gene

CVC1

Organism
Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.UniRule annotation

GO - Biological processi

Keywordsi

Biological processViral genome packaging, Virus exit from host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid vertex component 1UniRule annotation
Gene namesi
Name:CVC1UniRule annotation
Ordered Locus Names:ORF32
OrganismiHuman herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Taxonomic identifieri868565 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaeRhadinovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000000942 Componenti: Genome

Subcellular locationi

  • Virion UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004237851 – 454Capsid vertex component 1Add BLAST454

Expressioni

Keywords - Developmental stagei

Late protein

Interactioni

Subunit structurei

Interacts (via C-terminus) with capsid vertex component 2/CVC2.UniRule annotation

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi275 – 280Poly-Pro6

Sequence similaritiesi

Belongs to the herpesviridae CVC1 protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG0900008I.

Family and domain databases

HAMAPiMF_04017. HSV_CVC1. 1 hit.
InterProiView protein in InterPro
IPR007640. UL17-like.
PfamiView protein in Pfam
PF04559. Herpes_UL17. 1 hit.

Sequencei

Sequence statusi: Complete.

F5HB39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAHAINERY VGPRCHRLAH VVLPRTFLLH HAIPLEPEII FSTYTRFSRS
60 70 80 90 100
PGSSRRLVVC GKRVLPGEEN QLASSPSGLA LSLPLFSHDG NFHPFDISVL
110 120 130 140 150
RISCPGSNLS LTVRFLYLSL VVAMGAGRNN ARSPTVDGVS PPEGAVAHPL
160 170 180 190 200
EELQRLARAT PDPALTRGPL QVLTGLLRAG SDGDRATHHM ALEAPGTVRG
210 220 230 240 250
ESLDPPVSQK GPARTRHRPP PVRLSFNPVN ADVPATWRDA TNVYSGAPYY
260 270 280 290 300
VCVYERGGRQ EDDWLPIPLS FPEEPVPPPP GLVFMDDLFI NTKQCDFVDT
310 320 330 340 350
LEAACRTQGY TLRQRVPVAI PRDAEIADAV KSHFLEACLV LRGLASEASA
360 370 380 390 400
WIRAATSPPL GRHACWMDVL GLWESRPHTL GLELRGVNCG GTDGDWLEIL
410 420 430 440 450
KQPDVQKTVS GSLVACVIVT PALEAWLVLP GGFAIKGRYR ASKEDLVFIR

GRYG
Length:454
Mass (Da):49,512
Last modified:June 28, 2011 - v1
Checksum:iC1C7C4E6B7E071F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF148805 Genomic DNA. Translation: ABD28883.1.
RefSeqiYP_001129385.1. NC_009333.1.

Genome annotation databases

GeneIDi4961479.
KEGGivg:4961479.

Similar proteinsi

Entry informationi

Entry nameiCVC1_HHV8P
AccessioniPrimary (citable) accession number: F5HB39
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 16, 2013
Last sequence update: June 28, 2011
Last modified: March 15, 2017
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families