ID   F5H8G7_HUMAN            Unreviewed;       175 AA.
AC   F5H8G7;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=Synaptotagmin 7 {ECO:0000313|Ensembl:ENSP00000443576.1};
DE   Flags: Fragment;
GN   Name=SYT7 {ECO:0000313|Ensembl:ENSP00000443576.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000443576.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000443576.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000443576.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AP002754; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003108; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003559; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; F5H8G7; -.
DR   SMR; F5H8G7; -.
DR   MassIVE; F5H8G7; -.
DR   PeptideAtlas; F5H8G7; -.
DR   ProteomicsDB; 27776; -.
DR   Antibodypedia; 2220; 287 antibodies from 33 providers.
DR   Ensembl; ENST00000545053.1; ENSP00000443576.1; ENSG00000011347.10.
DR   UCSC; uc058cdp.1; human.
DR   HGNC; HGNC:11514; SYT7.
DR   VEuPathDB; HostDB:ENSG00000011347; -.
DR   GeneTree; ENSGT00940000157180; -.
DR   HOGENOM; CLU_1535958_0_0_1; -.
DR   ChiTaRS; SYT7; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000011347; Expressed in islet of Langerhans and 115 other cell types or tissues.
DR   ExpressionAtlas; F5H8G7; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR001565; Synaptotagmin.
DR   PANTHER; PTHR10024; SYNAPTOTAGMIN; 1.
DR   PANTHER; PTHR10024:SF344; SYNAPTOTAGMIN-7; 1.
DR   PRINTS; PR00399; SYNAPTOTAGMN.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
PE   1: Evidence at protein level;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0007829|MaxQB:F5H8G7,
KW   ECO:0007829|PeptideAtlas:F5H8G7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          53..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         175
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000443576.1"
SQ   SEQUENCE   175 AA;  18894 MW;  E4722C7DBD7BDF0B CRC64;
     MYRDPEAASP GAPSRDVLLV SAIITVSLSV TVVLCGLCHW CQRKLGKRYK NSLETVGTPD
     SGRGRSEKKA IKLPAGGKAV NTAPVPGQTP HDESDRRTEP RSSVSDLVNS LTSEMLMLSP
     GSEEDEAHEG CSRENLGRIQ FSVGYNFQES TLTVKIMKAQ ELPAKDFSGT SDPFV
//