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Protein
Submitted name:

Set1/Ash2 histone methyltransferase complex subunit ASH2

Gene

ASH2L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Set1/Ash2 histone methyltransferase complex subunit ASH2Imported
Gene namesi
Name:ASH2LImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000129691.15
HGNCiHGNC:744 ASH2L

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000129691

PTM / Processingi

Proteomic databases

EPDiF5H8F7
MaxQBiF5H8F7
PeptideAtlasiF5H8F7
PRIDEiF5H8F7

Expressioni

Gene expression databases

BgeeiENSG00000129691
ExpressionAtlasiF5H8F7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H8F7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini221 – 444B30.2/SPRYInterPro annotationAdd BLAST224

Phylogenomic databases

eggNOGiKOG2626 Eukaryota
ENOG410Y5GC LUCA
GeneTreeiENSGT00390000010474

Family and domain databases

InterProiView protein in InterPro
IPR037353 ASH2
IPR001870 B30.2/SPRY
IPR013320 ConA-like_dom_sf
IPR003877 SPRY_dom
PANTHERiPTHR10598 PTHR10598, 1 hit
PfamiView protein in Pfam
PF00622 SPRY, 2 hits
SMARTiView protein in SMART
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 2 hits
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit

Sequencei

Sequence statusi: Complete.

F5H8F7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNYSFHCNV CHHSGNTYFL RKQANLKEMC LSALANLTWQ SRTQDEHPKT
60 70 80 90 100
MFSKDKDIIP FIDKYWECMT TRQRPGKMTW PNNIVKTMSK ERDVFLVKEH
110 120 130 140 150
PDPGSKDPEE DYPKFGLLDQ DLSNIGPAYD NQKQSSAVST SGNLNGGIAA
160 170 180 190 200
GSSGKGRGAK RKQQDGGTTG TTKKARSDPL FSAQRLPPHG YPLEHPFNKD
210 220 230 240 250
GYRYILAEPD PHAPDPEKLE LDCWAGKPIP GDLYRACLYE RVLLALHDRA
260 270 280 290 300
PQLKISDDRL TVVGEKGYSM VRASHGVRKG AWYFEITVDE MPPDTAARLG
310 320 330 340 350
WSQPLGNLQA PLGYDKFSYS WRSKKGTKFH QSIGKHYSSG YGQGDVLGFY
360 370 380 390 400
INLPEDTETA KSLPDTYKDK ALIKFKSYLY FEEKDFVDKA EKSLKQTPHS
410 420 430 440 450
EIIFYKNGVN QGVAYKDIFE GVYFPAISLY KSCTVSINFG PCFKYPPKDL
460 470 480
TYRPMSDMGW GAVVEHTLAD VLYHVETEVD GRRSPPWEP
Length:489
Mass (Da):55,324
Last modified:June 28, 2011 - v1
Checksum:iE8D0D1018E9FFE9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084024 Genomic DNA No translation available.
AP006545 Genomic DNA No translation available.
RefSeqiNP_001269201.1, NM_001282272.1
UniGeneiHs.521530

Genome annotation databases

EnsembliENST00000545394; ENSP00000443606; ENSG00000129691
GeneIDi9070
UCSCiuc011lbk.3 human

Similar proteinsi

Entry informationi

Entry nameiF5H8F7_HUMAN
AccessioniPrimary (citable) accession number: F5H8F7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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