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Protein
Submitted name:

Ribosomal protein S6 kinase delta-1

Gene

RPS6KC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ribosomal protein S6 kinase delta-1Imported
Gene namesi
Name:RPS6KC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:10439. RPS6KC1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000136643.

PTM / Processingi

Proteomic databases

MaxQBiF5H7T0.
PeptideAtlasiF5H7T0.
PRIDEiF5H7T0.

Expressioni

Gene expression databases

BgeeiENSG00000136643.
ExpressionAtlasiF5H7T0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000355927.

Structurei

3D structure databases

ProteinModelPortaliF5H7T0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini582 – 844Protein kinaseInterPro annotationAdd BLAST263

Phylogenomic databases

eggNOGiKOG0603. Eukaryota.
KOG2101. Eukaryota.
ENOG410ZH1N. LUCA.
GeneTreeiENSGT00530000063268.

Family and domain databases

Gene3Di1.20.58.280. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR007330. MIT.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF04212. MIT. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00745. MIT. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF116846. SSF116846. 1 hit.
SSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5H7T0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASNQNSPIR TFGLNLSSDS SALGAVASDS EQSKTEEERE SRSLFPGSLK
60 70 80 90 100
PKLGKRDYLE KAGELIKLAL KKEEEDDYEA ASDFYRKGVD LLLEGVQGES
110 120 130 140 150
SPTRREAVKR RTAEYLMRAE SISSLYGKPQ LDDVSQVLLV MDTRTEQTFI
160 170 180 190 200
LKGLRKSSEY SRNRKTIIPR CVPNMVCLHK YIISEESVFL VLQHAEGGKL
210 220 230 240 250
WSYISKFLNR SPEESFDIKE VKKPTLAKVH LQQPTSSPQD SSSFESRGSD
260 270 280 290 300
GGSMLKALPL KSSLTPSSQD DSNQEDDGQD SSPKWPDSGS SSEEECTTSY
310 320 330 340 350
LTLCNEYGQE KIEPGSLNEE PFMKTEGNGV DTKAIKSFPA HLAADSDSPS
360 370 380 390 400
TQLRAHELKF FPNDDPEAVS SPRTSDSLSR SKNSPMEFFR IDSKDSASEL
410 420 430 440 450
LGLDFGEKLY SLKSEPLKPF FTLPDGDSAS RSFNTSESKV EFKAQDTISR
460 470 480 490 500
GSDDSVPVIS FKDAAFDDVS GTDEGRPDLL VNLPGELEST REAAAMGPTK
510 520 530 540 550
FTQTNIGIIE NKLLEAPDVL CLRLSTEQCQ AHEEKGIEEL SDPSGPKSYS
560 570 580 590 600
ITEKHYAQED PRMLFVAAVD HSSSGDMSLL PSSDPKFQGL GVVESAVTAN
610 620 630 640 650
NTEESLFRIC SPLSGANEYI ASTDTLKTEE VLLFTDQTDD LAKEEPTSLF
660 670 680 690 700
QRDSETKGES GLVLEGDKEI HQIFEDLDKK LALASRFYIP EGCIQRWAAE
710 720 730 740 750
MVVALDALHR EGIVCRDLNP NNILLNDRGH IQLTYFSRWS EVEDSCDSDA
760 770 780 790 800
IERMYCAPEV GAITEETEAC DWWSLGAVLF ELLTGKTLVE CHPAGINTHT
810 820 830 840 850
TLNMPECVSE EARSLIQQLL QFNPLERLGA GVAGVEDIKS HPFFTPVDWA

ELMR
Length:854
Mass (Da):94,457
Last modified:June 28, 2011 - v1
Checksum:i7E38DB084E2D4D1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL512449 Genomic DNA. No translation available.
AL583826 Genomic DNA. No translation available.
AL645860 Genomic DNA. No translation available.
KF510209 Genomic DNA. No translation available.
RefSeqiNP_001274147.1. NM_001287218.1.
NP_001274148.1. NM_001287219.1.
XP_016856517.1. XM_017001028.1.
UniGeneiHs.591416.

Genome annotation databases

EnsembliENST00000543470; ENSP00000442306; ENSG00000136643.
ENST00000614059; ENSP00000483873; ENSG00000136643.
GeneIDi26750.
UCSCiuc010pts.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL512449 Genomic DNA. No translation available.
AL583826 Genomic DNA. No translation available.
AL645860 Genomic DNA. No translation available.
KF510209 Genomic DNA. No translation available.
RefSeqiNP_001274147.1. NM_001287218.1.
NP_001274148.1. NM_001287219.1.
XP_016856517.1. XM_017001028.1.
UniGeneiHs.591416.

3D structure databases

ProteinModelPortaliF5H7T0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000355927.

Proteomic databases

MaxQBiF5H7T0.
PeptideAtlasiF5H7T0.
PRIDEiF5H7T0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000543470; ENSP00000442306; ENSG00000136643.
ENST00000614059; ENSP00000483873; ENSG00000136643.
GeneIDi26750.
UCSCiuc010pts.4. human.

Organism-specific databases

CTDi26750.
HGNCiHGNC:10439. RPS6KC1.
OpenTargetsiENSG00000136643.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0603. Eukaryota.
KOG2101. Eukaryota.
ENOG410ZH1N. LUCA.
GeneTreeiENSGT00530000063268.

Miscellaneous databases

ChiTaRSiRPS6KC1. human.
GenomeRNAii26750.

Gene expression databases

BgeeiENSG00000136643.
ExpressionAtlasiF5H7T0. baseline and differential.

Family and domain databases

Gene3Di1.20.58.280. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR007330. MIT.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF04212. MIT. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00745. MIT. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF116846. SSF116846. 1 hit.
SSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF5H7T0_HUMAN
AccessioniPrimary (citable) accession number: F5H7T0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 30, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.