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Protein
Submitted name:

Zinc finger protein 423

Gene

ZNF423

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein 423Imported
Gene namesi
Name:ZNF423Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:16762. ZNF423.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000102935.

PTM / Processingi

Proteomic databases

PeptideAtlasiF5H7S1.
PRIDEiF5H7S1.

Expressioni

Gene expression databases

BgeeiENSG00000102935.
ExpressionAtlasiF5H7S1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000262383.

Structurei

3D structure databases

ProteinModelPortaliF5H7S1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 48C2H2-typeInterPro annotationAdd BLAST28
Domaini49 – 76C2H2-typeInterPro annotationAdd BLAST28
Domaini77 – 104C2H2-typeInterPro annotationAdd BLAST28
Domaini105 – 132C2H2-typeInterPro annotationAdd BLAST28
Domaini146 – 174C2H2-typeInterPro annotationAdd BLAST29
Domaini178 – 206C2H2-typeInterPro annotationAdd BLAST29
Domaini363 – 391C2H2-typeInterPro annotationAdd BLAST29
Domaini400 – 423C2H2-typeInterPro annotationAdd BLAST24
Domaini515 – 537C2H2-typeInterPro annotationAdd BLAST23
Domaini545 – 567C2H2-typeInterPro annotationAdd BLAST23
Domaini575 – 599C2H2-typeInterPro annotationAdd BLAST25
Domaini603 – 631C2H2-typeInterPro annotationAdd BLAST29
Domaini633 – 661C2H2-typeInterPro annotationAdd BLAST29
Domaini664 – 691C2H2-typeInterPro annotationAdd BLAST28
Domaini690 – 713C2H2-typeInterPro annotationAdd BLAST24
Domaini769 – 796C2H2-typeInterPro annotationAdd BLAST28
Domaini813 – 840C2H2-typeInterPro annotationAdd BLAST28
Domaini842 – 869C2H2-typeInterPro annotationAdd BLAST28
Domaini1003 – 1031C2H2-typeInterPro annotationAdd BLAST29
Domaini1051 – 1078C2H2-typeInterPro annotationAdd BLAST28
Domaini1081 – 1108C2H2-typeInterPro annotationAdd BLAST28
Domaini1112 – 1140C2H2-typeInterPro annotationAdd BLAST29
Domaini1142 – 1167C2H2-typeInterPro annotationAdd BLAST26

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000129874.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
3.30.40.10. 1 hit.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF13912. zf-C2H2_6. 3 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 29 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 27 hits.
PS50157. ZINC_FINGER_C2H2_2. 23 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5H7S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGDGCDLGL GEEEGGTGLP YPCQFCDKSF IRLSYLKRHE QIHSDKLPFK
60 70 80 90 100
CTYCSRLFKH KRSRDRHIKL HTGDKKYHCH ECEAAFSRSD HLKIHLKTHS
110 120 130 140 150
SSKPFKCTVC KRGFSSTSSL QSHMQAHKKN KEHLAKSEKE AKKDDFMCDY
160 170 180 190 200
CEDTFSQTEE LEKHVLTRHP QLSEKADLQC IHCPEVFVDE NTLLAHIHQA
210 220 230 240 250
HANQKHKCPM CPEQFSSVEG VYCHLDSHRQ PDSSNHSVSP DPVLGSVASM
260 270 280 290 300
SSATPDSSAS VERGSTPDST LKPLRGQKKM RDDGQGWTKV VYSCPYCSKR
310 320 330 340 350
DFNSLAVLEI HLKTIHADKP QQSHTCQICL DSMPTLYNLN EHVRKLHKNH
360 370 380 390 400
AYPVMQFGNI SAFHCNYCPE MFADINSLQE HIRVSHCGPN ANPSDGNNAF
410 420 430 440 450
FCNQCSMGFL TESSLTEHIQ QAHCSVGSAK LESPVVQPTQ SFMEVYSCPY
460 470 480 490 500
CTNSPIFGSI LKLTKHIKEN HKNIPLAHSK KSKAEQSPVS SDVEVSSPKR
510 520 530 540 550
QRLSASANSI SNGEYPCNQC DLKFSNFESF QTHLKLHLEL LLRKQACPQC
560 570 580 590 600
KEDFDSQESL LQHLTVHYMT TSTHYVCESC DKQFSSVDDL QKHLLDMHTF
610 620 630 640 650
VLYHCTLCQE VFDSKVSIQV HLAVKHSNEK KMYRCTACNW DFRKEADLQV
660 670 680 690 700
HVKHSHLGNP AKAHKCIFCG ETFSTEVELQ CHITTHSKKY NCKFCSKAFH
710 720 730 740 750
AIILLEKHLR EKHCVFDAAT ENGTANGVPP MATKKAEPAD LQGMLLKNPE
760 770 780 790 800
APNSHEASED DVDASEPMYG CDICGAAYTM EVLLQNHRLR DHNIRPGEDD
810 820 830 840 850
GSRKKAEFIK GSHKCNVCSR TFFSENGLRE HLQTHRGPAK HYMCPICGER
860 870 880 890 900
FPSLLTLTEH KVTHSKSLDT GTCRICKMPL QSEEEFIEHC QMHPDLRNSL
910 920 930 940 950
TGFRCVVCMQ TVTSTLELKI HGTFHMQKLA GSSAASSPNG QGLQKLYKCA
960 970 980 990 1000
LCLKEFRSKQ DLVKLDVNGL PYGLCAGCMA RSANGQVGGL APPEPADRPC
1010 1020 1030 1040 1050
AGLRCPECSV KFESAEDLES HMQVDHRDLT PETSGPRKGT QTSPVPRKKT
1060 1070 1080 1090 1100
YQCIKCQMTF ENEREIQIHV ANHMIEEGIN HECKLCNQMF DSPAKLLCHL
1110 1120 1130 1140 1150
IEHSFEGMGG TFKCPVCFTV FVQANKLQQH IFAVHGQEDK IYDCSQCPQK
1160
FFFQTELQNH TMSQHAQ
Length:1,167
Mass (Da):131,673
Last modified:June 28, 2011 - v1
Checksum:i39B62D925E990DA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007339 Genomic DNA. No translation available.
AC007603 Genomic DNA. No translation available.
AC007607 Genomic DNA. No translation available.
AC007861 Genomic DNA. No translation available.
AC027348 Genomic DNA. No translation available.
KF456193 Genomic DNA. No translation available.
RefSeqiNP_001317462.1. NM_001330533.1.
UniGeneiHs.443715.
Hs.530930.
Hs.744482.

Genome annotation databases

EnsembliENST00000535559; ENSP00000442321; ENSG00000102935.
ENST00000567169; ENSP00000455061; ENSG00000102935.
GeneIDi23090.
UCSCiuc010vgn.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007339 Genomic DNA. No translation available.
AC007603 Genomic DNA. No translation available.
AC007607 Genomic DNA. No translation available.
AC007861 Genomic DNA. No translation available.
AC027348 Genomic DNA. No translation available.
KF456193 Genomic DNA. No translation available.
RefSeqiNP_001317462.1. NM_001330533.1.
UniGeneiHs.443715.
Hs.530930.
Hs.744482.

3D structure databases

ProteinModelPortaliF5H7S1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000262383.

Proteomic databases

PeptideAtlasiF5H7S1.
PRIDEiF5H7S1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000535559; ENSP00000442321; ENSG00000102935.
ENST00000567169; ENSP00000455061; ENSG00000102935.
GeneIDi23090.
UCSCiuc010vgn.4. human.

Organism-specific databases

CTDi23090.
HGNCiHGNC:16762. ZNF423.
OpenTargetsiENSG00000102935.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000129874.

Miscellaneous databases

ChiTaRSiZNF423. human.
GenomeRNAii23090.

Gene expression databases

BgeeiENSG00000102935.
ExpressionAtlasiF5H7S1. baseline and differential.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
3.30.40.10. 1 hit.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF13912. zf-C2H2_6. 3 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 29 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 27 hits.
PS50157. ZINC_FINGER_C2H2_2. 23 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF5H7S1_HUMAN
AccessioniPrimary (citable) accession number: F5H7S1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 30, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.