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F5H7B7

- F5H7B7_HUMAN

UniProt

F5H7B7 - F5H7B7_HUMAN

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Protein
Submitted name:

ATP-binding cassette sub-family A member 13

Gene

ABCA13

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. ATPase activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette sub-family A member 13Imported
Gene namesi
Name:ABCA13Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:14638. ABCA13.

PTM / Processingi

Proteomic databases

PRIDEiF5H7B7.

Expressioni

Gene expression databases

BgeeiF5H7B7.

Structurei

3D structure databases

ProteinModelPortaliF5H7B7.
SMRiF5H7B7. Positions 378-673.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR19229. PTHR19229. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F5H7B7 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
XYPNPISTHS GPQDIKWEII HEVIPFLDKI LSQNSTEIGS FLKMVICLTL
60 70 80 90 100
EALWKNLKKD NWNVSNVLMT FTQHPNNLLK TIETVLEASS GIKSDYEGDL
110 120 130 140 150
NKSLYFDTPL SQNITHHQLE KAIHNVLSRI ALWRKGLLFN NSEWITSTRT
160 170 180 190 200
LFQPLFEIFI KATTGKNVTS EKEERTKKEM IDFPYSFKPF FCLEKYLGGL
210 220 230 240 250
FVLTKYWQQI PLTDQSVVEI CEVFQQTVKP SEAMEMLQKV KMMVVRVLTI
260 270 280 290 300
VAENPSWTKD ILCATLSCKQ NGIRHLILSA IQGVTLAQDH FQEIEKIWSS
310 320 330 340 350
PNQLNCESLS KNLSSTLESF KSSLENATGQ DCTSQPRLET VQQHLYMLAK
360 370 380 390 400
SLEETWSSGN PIMTFLSNFT VTEDVKIKDL MKNITKLTEE LRSSIQISNE
410 420 430 440 450
TIHSILEANI SHSKVLFSAL TVALSGKCDQ EILHLLLTFP KGEKSWIAAE
460 470 480 490 500
ELCSLPGSKV YSLIVLLSRN LDVRAFIYKT LMPSEANGLL NSLLDIVSSL
510 520 530 540 550
SALLAKAQHV FEYLPEFLHT FKITALLETL DFQQVSQNVQ ARSSAFGSFQ
560 570 580 590 600
FVMKMVCKDQ ASFLSDSNMF INLPRVKELL EDDKEKFNIP EDSTPFCLKL
610 620 630 640 650
YQEILQLPNG ALVWTFLKPI LHGKILYTPN TPEINKVIQK ANYTFYIVDK
660 670 680 690 700
LKTLSETLLE MSSLFQRSGS GQMFNQLQEA LRNKFVRNFV ENQLHIDVDK
710 720 730 740 750
LTEKLQTYGG LLDEMFNHAG AGRFRFLGSI LVNLSSCVAL NRFQALQSVD
760 770 780 790 800
ILETKAHELL QQNSFLASII FSNSLFDKNF RSESVKLPPH VSYTIRTNVL
810 820 830 840 850
YSVRTDVVKN PSWKFHPQNL PADGFKYNYV FAPLQDMIER AIILVQTGQE
860 870 880 890 900
ALEPAAQTQA APYPCHTSDL FLNNVGFFFP LIMMLTWMVS VASMVRKLVY
910 920 930 940 950
EQEIQIEEYM RMMGVHPVIH FLAWFLENMA VLTISSATLA IVLKTSGIFA
960 970 980 990 1000
HSNTFIVFLF LLDFGMSVVM LSYLLSAFFS QANTAALCTS LVYMISFLPY
1010 1020 1030 1040 1050
IVLLVLHNQL SFVNQTFLCL LSTTAFGQGV FFITFLEGQE TGIQWNNMYQ
1060 1070 1080 1090 1100
ALEQGGMTFG WVCWMILFDS SLYFLCGWYL SNLIPGTFGL RKPWYFPFTA
1110 1120 1130 1140 1150
SYWKSVGFLV EKRQYFLSSS LFFFNENFDN KGSSLQNREG ELEGSAPGVT
1160 1170 1180 1190 1200
LVSVTKEYEG HKAVVQDLSL TFYRDQITAL LGTNGAGKTT IISMLTGLHP
1210 1220 1230 1240 1250
PTSGTIIING KNLQTDLSRV RMELGVCPQQ DILLDNLTVR EHLLLFASIK
1260 1270 1280 1290 1300
APQWTKKELH QQVNQTLQDV DLTQHQHKQT RALSGGLKRK LSLGIAFMGM
1310 1320 1330 1340 1350
SRTVVLDEPT SGVDPCSRHS LWDILLKYRE GRTIIFTTHH LDEAEALSDR
1360 1370 1380 1390 1400
VAVLQHGRLR CCGPPFCLKE AYGQGLRLTL TRQPSVLEAH DLKDMACVTS
1410 1420 1430 1440 1450
LIKIYIPQAF LKDSSGSELT YTIPKDTDKA CLKGLFQALD ENLHQLHLTG
1460 1470 1480 1490 1500
YGISDTTLEE VFLMLLQDSN KKSHIALGTE SELQNHRPTG HLSGYCGSLA
1510 1520 1530 1540 1550
RPATVQGVQL LRAQVAAILA RRLRRTLRAG KSTLADLLLP VLFVALAMGL
1560 1570 1580 1590 1600
FMVRPLATEY PPLRLTPGHY QRAETYFFSS SGGDNLDLTR VLLRKFRDQD
1610 1620 1630 1640 1650
LPCADLNPRQ KNSSCWRTDP FSHPEFQDSC GCLKCPNRSA SAPYLTNHLG
1660 1670 1680 1690 1700
HTLLNLSGFN MEEYLLAPSE KPRLGGWSFG LKIPSEAGGA NGNISKPPTL
1710 1720 1730 1740 1750
AKVWYNQKGF HSLPSYLNHL NNLILWQHLP PTVDWRQYGI TLYSHPYGGA
1760 1770 1780 1790 1800
LLNEDKILES IRQCGVALCI VLGFSILSAS IGSSVVRDRV IGAKRLQHIS
1810 1820 1830 1840 1850
GLGYRMYWFT NFLYDMLFYL VSVCLCVAVI VAFQLTAFTF RKNLAATALL
1860 1870 1880 1890 1900
LSLFGYATLP WMYLMSRIFS SSDVAFISYV SLNFIFGLCT MLITIMPRLL
1910 1920 1930 1940 1950
AIISKAKNLQ NIYDVLKWVF TIFPQFCLGQ GLVELCYNQI KYDLTHNFGI
1960 1970 1980 1990 2000
DSYVSPFEMN FLGWIFVQLA SQGTVLLLLR VLLHWDLLRW PRGHSTLQGT
2010 2020 2030 2040 2050
VKSSKDTDVE KEEKRVFEGR TNGDILVLYN LSKHYRRFFQ NIIAVQDISL
2060 2070 2080 2090 2100
GIPKGECFGL LGVNGAGKST TFKMLNGEVS LTSGHAIIRT PMGDAVDLSS
2110 2120 2130 2140 2150
AGTAGVLIGY CPQQDALDEL LTGWEHLYYY CSLRGIPRQC IPEVAGDLIR
2160 2170 2180 2190 2200
RLHLEAHADK PVATYSGGTK RKLSTALALV GKPDILLLDE PSSGMDPCSK
2210 2220 2230 2240 2250
RYLWQTIMKE VREGCAAVLT SHSMEECEAL CTRLAIMVNG SFKCLGSPQH
2260 2270 2280 2290 2300
IKNRFGDGYT VKVWLCKEAN QHCTVSDHLK LYFPGIQFKG QHLNLLEYHV
2310 2320 2330 2340 2350
PKRWGCLADL FKVIENNKTF LNIKHYSINQ TTLEQVFINF ASEQQQTLQS
2360
TLDPSTDSHH THHLPI
Length:2,366
Mass (Da):266,998
Last modified:October 29, 2014 - v2
Checksum:i591305763CF02363
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC073424 Genomic DNA. No translation available.
AC073927 Genomic DNA. No translation available.
AC091770 Genomic DNA. No translation available.
AC095039 Genomic DNA. No translation available.
AC232300 Genomic DNA. No translation available.
AC232312 Genomic DNA. No translation available.
FJ770081 Genomic DNA. No translation available.
KF458461 Genomic DNA. No translation available.
KF511036 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000544596; ENSP00000442634; ENSG00000179869.
UCSCiuc010kyu.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC073424 Genomic DNA. No translation available.
AC073927 Genomic DNA. No translation available.
AC091770 Genomic DNA. No translation available.
AC095039 Genomic DNA. No translation available.
AC232300 Genomic DNA. No translation available.
AC232312 Genomic DNA. No translation available.
FJ770081 Genomic DNA. No translation available.
KF458461 Genomic DNA. No translation available.
KF511036 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali F5H7B7.
SMRi F5H7B7. Positions 378-673.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F5H7B7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000544596 ; ENSP00000442634 ; ENSG00000179869 .
UCSCi uc010kyu.1. human.

Organism-specific databases

HGNCi HGNC:14638. ABCA13.
GenAtlasi Search...

Miscellaneous databases

ChiTaRSi ABCA13. human.
NextBioi 35509349.

Gene expression databases

Bgeei F5H7B7.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR19229. PTHR19229. 1 hit.
Pfami PF00005. ABC_tran. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF5H7B7_HUMAN
AccessioniPrimary (citable) accession number: F5H7B7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: October 29, 2014
Last modified: October 29, 2014
This is version 26 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3