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Protein
Submitted name:

Tumor necrosis factor receptor superfamily member 1A

Gene

TNFRSF1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor receptor superfamily member 1AImported
Gene namesi
Name:TNFRSF1AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000067182.7.
HGNCiHGNC:11916. TNFRSF1A.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000067182.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi75 ↔ 90PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

MaxQBiF5H6Z2.
PeptideAtlasiF5H6Z2.
PRIDEiF5H6Z2.

Expressioni

Gene expression databases

BgeeiENSG00000067182.
ExpressionAtlasiF5H6Z2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF5H6Z2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 116TNFR-CysInterPro annotationAdd BLAST43
Repeati74 – 116TNFR-CysPROSITE-ProRule annotationAdd BLAST43

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00530000064001.

Family and domain databases

InterProiView protein in InterPro
IPR001368. TNFR/NGFR_Cys_rich_reg.
PfamiView protein in Pfam
PF00020. TNFR_c6. 1 hit.
SMARTiView protein in SMART
SM00208. TNFR. 2 hits.
PROSITEiView protein in PROSITE
PS00652. TNFR_NGFR_1. 1 hit.
PS50050. TNFR_NGFR_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

F5H6Z2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSTVPDLL LPLVLLELLV GIYPSGVIGL VPHLGDREKR DSVCPQGKYI
60 70 80 90 100
HPQNNSICCT KCHKGPGQDT DCRECESGSF TASENHLRHC LSCSKCRKEM
110
GQVEISSCTV DRDTVCGC
Length:118
Mass (Da):12,820
Last modified:June 28, 2011 - v1
Checksum:i144161C6D28BB140
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei118Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006057 Genomic DNA. No translation available.
KF455591 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000536194; ENSP00000442919; ENSG00000067182.
UCSCiuc058kde.1. human.

Entry informationi

Entry nameiF5H6Z2_HUMAN
AccessioniPrimary (citable) accession number: F5H6Z2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 27, 2017
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported