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Protein
Submitted name:

Neutral alpha-glucosidase AB

Gene

GANAB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Names & Taxonomyi

Protein namesi
Submitted name:
Neutral alpha-glucosidase ABImported
Gene namesi
Name:GANABImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000089597.16
HGNCiHGNC:4138 GANAB

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000089597

PTM / Processingi

Proteomic databases

MaxQBiF5H6X6
PeptideAtlasiF5H6X6
PRIDEiF5H6X6

Expressioni

Gene expression databases

BgeeiENSG00000089597
ExpressionAtlasiF5H6X6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H6X6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini157 – 227Gal_mutarotas_2InterPro annotationAdd BLAST71

Sequence similaritiesi

Belongs to the glycosyl hydrolase 31 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1066 Eukaryota
COG1501 LUCA
GeneTreeiENSGT00760000119229

Family and domain databases

Gene3Di2.60.40.1180, 2 hits
InterProiView protein in InterPro
IPR011013 Gal_mutarotase_sf_dom
IPR000322 Glyco_hydro_31
IPR030458 Glyco_hydro_31_AS
IPR030459 Glyco_hydro_31_CS
IPR025887 Glyco_hydro_31_N_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF13802 Gal_mutarotas_2, 1 hit
PF01055 Glyco_hydro_31, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF74650 SSF74650, 2 hits
PROSITEiView protein in PROSITE
PS00129 GLYCOSYL_HYDROL_F31_1, 1 hit
PS00707 GLYCOSYL_HYDROL_F31_2, 1 hit

Sequencei

Sequence statusi: Complete.

F5H6X6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRFRIDELE PRRPRYRVPD VLVADPPIAR LSVSGRDENS VELTMAEGPY
60 70 80 90 100
KIILTARPFR LDLLEDRSLL LSVNARGLLE FEHQRAPRVS QGSKDPAEGD
110 120 130 140 150
GAQPEETPRD GDKPEETQGK AEKDEPGAWE ETFKTHSDSK PYGPMSVGLD
160 170 180 190 200
FSLPGMEHVY GIPEHADNLR LKVTEGGEPY RLYNLDVFQY ELYNPMALYG
210 220 230 240 250
SVPVLLAHNP HRDLGIFWLN AAETWVDISS NTAGKTLFGK MMDYLQGSGE
260 270 280 290 300
TPQTDVRWMS ETGIIDVFLL LGPSISDVFR QYASLTGTQA LPPLFSLGYH
310 320 330 340 350
QSRWNYRDEA DVLEVDQGFD DHNLPCDVIW LDIEHADGKR YFTWDPSRFP
360 370 380 390 400
QPRTMLERLA SKRRKLVAIV DPHIKVDSGY RVHEELRNLG LYVKTRDGSD
410 420 430 440 450
YEGWCWPGSA GYPDFTNPTM RAWWANMFSY DNYEGSAPNL FVWNDMNEPS
460 470 480 490 500
VFNGPEVTML KDAQHYGGWE HRDVHNIYGL YVHMATADGL RQRSGGMERP
510 520 530 540 550
FVLARAFFAG SQRFGAVWTG DNTAEWDHLK ISIPMCLSLG LVGLSFCGAD
560 570 580 590 600
VGGFFKNPEP ELLVRWYQMG AYQPFFRAHA HLDTGRREPW LLPSQHNDII
610 620 630 640 650
RDALGQRYSL LPFWYTLLYQ AHREGIPVMR PLWVQYPQDV TTFNIDDQYL
660 670 680 690 700
LGDALLVHPV SDSGAHGVQV YLPGQGEVWY DIQSYQKHHG PQTLYLPVTL
710 720 730 740 750
SSIPVFQRGG TIVPRWMRVR RSSECMKDDP ITLFVALSPQ GTAQGELFLD
760 770 780 790 800
DGHTFNYQTR QEFLLRRFSF SGNTLVSSSA DPEGHFETPI WIERVVIIGA
810 820 830 840
GKPAAVVLQT KGSPESRLSF QHDPETSVLV LRKPGINVAS DWSIHLR
Length:847
Mass (Da):96,216
Last modified:June 28, 2011 - v1
Checksum:i68FE62252A5B076E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001458 Genomic DNA No translation available.
RefSeqiNP_001265123.1, NM_001278194.1
NP_001316151.1, NM_001329222.1
NP_001316152.1, NM_001329223.1
XP_016872901.1, XM_017017412.1
UniGeneiHs.595071

Genome annotation databases

EnsembliENST00000540933; ENSP00000442962; ENSG00000089597
GeneIDi23193
UCSCiuc001nuc.5 human

Similar proteinsi

Entry informationi

Entry nameiF5H6X6_HUMAN
AccessioniPrimary (citable) accession number: F5H6X6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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