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Protein
Submitted name:

Neutral alpha-glucosidase AB

Gene

GANAB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Names & Taxonomyi

Protein namesi
Submitted name:
Neutral alpha-glucosidase ABImported
Gene namesi
Name:GANABImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:4138. GANAB.

PTM / Processingi

Proteomic databases

PaxDbiF5H6X6.
PeptideAtlasiF5H6X6.
PRIDEiF5H6X6.

Expressioni

Gene expression databases

BgeeiENSG00000089597.
ExpressionAtlasiF5H6X6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000340466.

Structurei

3D structure databases

ProteinModelPortaliF5H6X6.
SMRiF5H6X6. Positions 142-814.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini157 – 22771Gal_mutarotas_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 31 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1066. Eukaryota.
COG1501. LUCA.
GeneTreeiENSGT00760000119229.

Family and domain databases

InterProiIPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR030458. Glyco_hydro_31_AS.
IPR030459. Glyco_hydro_31_CS.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 2 hits.
PROSITEiPS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F5H6X6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRFRIDELE PRRPRYRVPD VLVADPPIAR LSVSGRDENS VELTMAEGPY
60 70 80 90 100
KIILTARPFR LDLLEDRSLL LSVNARGLLE FEHQRAPRVS QGSKDPAEGD
110 120 130 140 150
GAQPEETPRD GDKPEETQGK AEKDEPGAWE ETFKTHSDSK PYGPMSVGLD
160 170 180 190 200
FSLPGMEHVY GIPEHADNLR LKVTEGGEPY RLYNLDVFQY ELYNPMALYG
210 220 230 240 250
SVPVLLAHNP HRDLGIFWLN AAETWVDISS NTAGKTLFGK MMDYLQGSGE
260 270 280 290 300
TPQTDVRWMS ETGIIDVFLL LGPSISDVFR QYASLTGTQA LPPLFSLGYH
310 320 330 340 350
QSRWNYRDEA DVLEVDQGFD DHNLPCDVIW LDIEHADGKR YFTWDPSRFP
360 370 380 390 400
QPRTMLERLA SKRRKLVAIV DPHIKVDSGY RVHEELRNLG LYVKTRDGSD
410 420 430 440 450
YEGWCWPGSA GYPDFTNPTM RAWWANMFSY DNYEGSAPNL FVWNDMNEPS
460 470 480 490 500
VFNGPEVTML KDAQHYGGWE HRDVHNIYGL YVHMATADGL RQRSGGMERP
510 520 530 540 550
FVLARAFFAG SQRFGAVWTG DNTAEWDHLK ISIPMCLSLG LVGLSFCGAD
560 570 580 590 600
VGGFFKNPEP ELLVRWYQMG AYQPFFRAHA HLDTGRREPW LLPSQHNDII
610 620 630 640 650
RDALGQRYSL LPFWYTLLYQ AHREGIPVMR PLWVQYPQDV TTFNIDDQYL
660 670 680 690 700
LGDALLVHPV SDSGAHGVQV YLPGQGEVWY DIQSYQKHHG PQTLYLPVTL
710 720 730 740 750
SSIPVFQRGG TIVPRWMRVR RSSECMKDDP ITLFVALSPQ GTAQGELFLD
760 770 780 790 800
DGHTFNYQTR QEFLLRRFSF SGNTLVSSSA DPEGHFETPI WIERVVIIGA
810 820 830 840
GKPAAVVLQT KGSPESRLSF QHDPETSVLV LRKPGINVAS DWSIHLR
Length:847
Mass (Da):96,216
Last modified:June 28, 2011 - v1
Checksum:i68FE62252A5B076E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001458 Genomic DNA. No translation available.
RefSeqiNP_001265123.1. NM_001278194.1.
UniGeneiHs.595071.

Genome annotation databases

EnsembliENST00000540933; ENSP00000442962; ENSG00000089597.
GeneIDi23193.
UCSCiuc001nuc.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001458 Genomic DNA. No translation available.
RefSeqiNP_001265123.1. NM_001278194.1.
UniGeneiHs.595071.

3D structure databases

ProteinModelPortaliF5H6X6.
SMRiF5H6X6. Positions 142-814.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000340466.

Proteomic databases

PaxDbiF5H6X6.
PeptideAtlasiF5H6X6.
PRIDEiF5H6X6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000540933; ENSP00000442962; ENSG00000089597.
GeneIDi23193.
UCSCiuc001nuc.5. human.

Organism-specific databases

CTDi23193.
HGNCiHGNC:4138. GANAB.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1066. Eukaryota.
COG1501. LUCA.
GeneTreeiENSGT00760000119229.

Miscellaneous databases

ChiTaRSiGANAB. human.
GenomeRNAii23193.

Gene expression databases

BgeeiENSG00000089597.
ExpressionAtlasiF5H6X6. baseline and differential.

Family and domain databases

InterProiIPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR030458. Glyco_hydro_31_AS.
IPR030459. Glyco_hydro_31_CS.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 2 hits.
PROSITEiPS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF5H6X6_HUMAN
AccessioniPrimary (citable) accession number: F5H6X6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 7, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.